相关论文: Dual-LED-based multichannel microscopy for whole-s…

Multispectral imaging is very beneficial in diverse applications, like healthcare and agriculture, since it can capture absorption bands of molecules in different spectral areas. A promising approach for multispectral snapshot imaging are…

We propose a new design for a multi-color, parallelized STED microscope, capable of multiple beam scanning. Our design is based on a common programmable diffracting optical element used to split, shape, and align both the excitation beams…

The combination of different imaging modalities into single imaging platforms has a strong potential in biomedical sciences since it permits the analysis of complementary properties of the target sample. Here, we report on an extremely…

We present MetaSpectra+, a compact multifunctional camera that supports two operating modes: (1) snapshot HDR + hyperspectral or (2) snapshot polarization + hyperspectral imaging. It utilizes a novel metasurface-refractive assembly that…

Whole slide image (WSI) classification is a crucial problem for cancer diagnostics in clinics and hospitals. A WSI, acquired at gigapixel size, is commonly tiled into patches and processed by multiple-instance learning (MIL) models.…

Automatic medical image segmentation has wide applications for disease diagnosing. However, it is much more challenging than natural optical image segmentation due to the high-resolution of medical images and the corresponding huge…

Recent developments in stimulated emission depletion (STED) microscopy achieved nanometer scale resolution and showed great potential in live cell imaging. Yet, STED nanoscopy techniques are based on single point-scanning. This constitutes…

Multifocus microscopy enables recording of entire volumes in a single camera exposure. In dense samples, multifocus microscopy is severely hampered by background haze. Here, we introduce a scalable multifocus method that incorporates…

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

This article experimentally examines different configurations of a novel multi-camera array microscope (MCAM) imaging technology. The MCAM is based upon a densely packed array of "micro-cameras" to jointly image across a large field-of-view…

Multi-spectral imaging, which simultaneously captures the spatial and spectral information of a scene, is widely used across diverse fields, including remote sensing, biomedical imaging, and agricultural monitoring. Here, we introduce a…

We propose a dataset-based photonic simulation framework for multimode waveguide design, enabling ultra-fast simulations with high accuracy. Compared to conventional approaches, our method offers two to three orders of magnitude speed-up in…

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Deep-learning techniques have been used widely to alleviate the labour-intensive and time-consuming manual annotation required for pixel-level tissue characterization. Our previous study introduced an efficient single dynamic network -…

Diffusion MRI (dMRI) is a unique imaging technique for in vivo characterization of tissue microstructure and white matter pathways. However, its relatively long acquisition time implies greater motion artifacts when imaging, for example,…

Parallel imaging techniques have been widely used in high-field magnetic resonance imaging (MRI). Multiple receiver coils have been shown to improve image quality and allow accelerated image acquisition. Magnetic resonance imaging at…

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Different imaging modalities are used to extract the diverse information carried in an optical field. Two prominent modalities include bright field and phase contrast microscopy that can visualize the amplitude and phase features of a…

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…