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Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains. There…

分子网络 · 定量生物学 2016-12-28 Tahir I. Yusufaly , James Q. Boedicker

Microorganisms employ sophisticated mechanisms for intercellular communication and environmental sensing, with quorum sensing serving as a fundamental regulatory process. Dysregulation of quorum sensing has been implicated in various…

新兴技术 · 计算机科学 2025-09-30 O. Tansel Baydas , Efe Yatgin , Ozgur B. Akan

The exchange of small molecular signals within microbial populations is generally referred to as quorum sensing (QS). QS is ubiquitous in nature and enables microorganisms to respond to fluctuations in living environments by working…

细胞行为 · 定量生物学 2019-09-16 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang

Autoinducers are small signaling molecules that mediate intercellular communication in microbial populations and trigger coordinated gene expression via "quorum sensing". Elucidating the mechanisms that control autoinducer production is,…

种群与进化 · 定量生物学 2017-07-26 Matthias Bauer , Johannes Knebel , Matthias Lechner , Peter Pickl , Erwin Frey

Microbial communities play a significant role in bioremediation,plant growth,human and animal digestion,global elemental cycles including the carbon-cycle,and water treatment.They are also posed to be the engines of renewable energy via…

新兴技术 · 计算机科学 2016-01-12 Nicolò Michelusi , James Boedicker , Mohamed Y. El-Naggar , Urbashi Mitra

The design of biological networks using bacteria as the basic elements of the network is initially motivated by a phenomenon called quorum sensing. Through quorum sensing, each bacterium performs sensing the medium and communicating it to…

信息论 · 计算机科学 2012-05-23 Arash Einolghozati , Mohsen Sardari , Faramarz Fekri

Quorum sensing is a decentralized biological process, through which a community of cells with no global awareness coordinate their functional behaviors based solely on cell-medium interactions and local decisions. This paper draws…

机器学习 · 计算机科学 2015-10-08 Feng Tan , Jean-Jacques Slotine

Quorum sensing is the regulation of gene expression in response to changes in cell density. To measure their cell density, bacterial populations produce and detect diffusible molecules called autoinducers. Individual bacteria internally…

分子网络 · 定量生物学 2017-04-12 Thibaud Taillefumier , Ned S. Wingreen

In quorum sensing (QS), bacteria exchange molecular signals to work together. An analytically-tractable model is presented for characterizing QS signal propagation within a population of bacteria and the number of responsive cooperative…

信息论 · 计算机科学 2020-09-03 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang , Jing Guo

Within the context of evolution, an altruistic act that benefits the receiving individual at the expense of the acting individual is a puzzling phenomenon. An extreme form of altruism can be found in colicinogenic E. coli. These suicidal…

神经与进化计算 · 计算机科学 2016-03-31 Anya Elaine Johnson , Eli Strauss , Rodney Pickett , Christoph Adami , Ian Dworkin , Heather J. Goldsby

A spacially extended model of the collective behavior of a large number of locally acting organisms is proposed in which organisms move probabilistically between local cells in space, but with weights dependent on local morphogenetic…

adap-org · 物理学 2008-06-25 Mark M. Millonas

Quorum sensing (QS) mimickers can be used as an effective tool to disrupt biofilms which consist of communicating bacteria and extracellular polymeric substances. In this paper, a stochastic biofilm disruption model based on the usage of QS…

定量方法 · 定量生物学 2023-11-27 Fatih Gulec , Andrew W. Eckford

To explain the stability of cooperation is a central task of evolutionary theory. We investigate this question in the case of quorum sensing (QS) bacteria, which regulate cooperative traits in response to population density. Cooperation is…

种群与进化 · 定量生物学 2019-05-02 Burkhard A. Hense , Matthew McIntosh , Johannes Müller , Martin Schuster

Current bioacoustic AI systems achieve impressive cross-species performance by processing animal communication through transformer architectures, foundation model paradigms, and other computational approaches. However, these approaches…

人工智能 · 计算机科学 2025-11-13 Graham L. Bishop

The social organization of microorganisms has long been a fascinating and challenging subject in both biology and sociology. In these organisms, the role of the individual is far less dominant than that of the community, which functions as…

生物物理 · 物理学 2025-03-05 Eleonora Alfinito , Matteo Beccaria

Molecular Communication (MC) utilizes chemical molecules to transmit information, introducing innovative strategies for pharmaceutical interventions and enhanced immune system monitoring. This paper explores Molecular communication based…

生物大分子 · 定量生物学 2024-12-31 Shees Zulfiqar , Ozgur B. Akan

In many natural synchronization phenomena, communication between individual elements occurs not directly, but rather through the environment. One of these instances is bacterial quorum sensing, where bacteria release signaling molecules in…

动力系统 · 数学 2015-05-18 Giovanni Russo , Jean-Jacques E. Slotine

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

应用统计 · 统计学 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

A cooperative drug delivery system is proposed, where quorum sensing (QS), a density-dependent bacterial behavior coordination mechanism, is employed by synthetic bacterium-based nanomachines (B-NMs) for controllable drug delivery. In our…

定量方法 · 定量生物学 2023-03-15 Yuting Fang , Stuart T. Johnston , Matt Faria , Xinyu Huang , Andrew W. Eckford , Jamie Evans

"Secrete-and-sense cells" can communicate by secreting a signaling molecule while also producing a receptor that detects the molecule. The cell can potentially "talk" to itself ("self-communication") or talk to neighboring cells with the…

细胞行为 · 定量生物学 2017-08-10 Berkalp A. Doğaner , Lawrence K. Q. Yan , Hyun Youk
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