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We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

计算机视觉与模式识别 · 计算机科学 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga

State-of-the-art approaches for semantic image segmentation are built on Convolutional Neural Networks (CNNs). The typical segmentation architecture is composed of (a) a downsampling path responsible for extracting coarse semantic features,…

计算机视觉与模式识别 · 计算机科学 2017-11-01 Simon Jégou , Michal Drozdzal , David Vazquez , Adriana Romero , Yoshua Bengio

The ability to automatically detect certain types of cells or cellular subunits in microscopy images is of significant interest to a wide range of biomedical research and clinical practices. Cell detection methods have evolved from…

计算机视觉与模式识别 · 计算机科学 2018-02-22 Yao Xue , Nilanjan Ray

Retrospective analysis of brain MRI scans acquired in the clinic has the potential to enable neuroimaging studies with sample sizes much larger than those found in research datasets. However, analysing such clinical images "in the wild" is…

图像与视频处理 · 电气工程与系统科学 2023-01-06 Benjamin Billot , Magdamo Colin , Sean E. Arnold , Sudeshna Das , Juan. E. Iglesias

Brain extraction is a fundamental step for most brain imaging studies. In this paper, we investigate the problem of skull stripping and propose complementary segmentation networks (CompNets) to accurately extract the brain from T1-weighted…

计算机视觉与模式识别 · 计算机科学 2018-10-11 Raunak Dey , Yi Hong

Researchers in the field of connectomics are working to reconstruct a map of neural connections in the brain in order to understand at a fundamental level how the brain processes information. Constructing this wiring diagram is done by…

Compression is a standard procedure for making convolutional neural networks (CNNs) adhere to some specific computing resource constraints. However, searching for a compressed architecture typically involves a series of time-consuming…

图像与视频处理 · 电气工程与系统科学 2021-07-08 Suraj Mishra , Danny Z. Chen , X. Sharon Hu

The motivation of our work is to present a new visualization-guided computing paradigm to combine direct 3D volume processing and volume rendered clues for effective 3D exploration such as extracting and visualizing microstructures in-vivo.…

图形学 · 计算机科学 2020-09-15 Yifan Wang , Guoli Yan , Haikuan Zhu , Sagar Buch , Ying Wang , Ewart Mark Haacke , Jing Hua , Zichun Zhong

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

图像与视频处理 · 电气工程与系统科学 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

Automatic segmentation of diverse heterogeneous brain lesions using multi-modal MRI is a challenging problem in clinical neuroimaging, mainly because of the lack of generalizability and high prediction variance of pathology-specific deep…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Md. Mehedi Hassan , Shafqat Alam , Shahriar Ahmed Seam , Maruf Ahmed

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

神经元与认知 · 定量生物学 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

One of the central problems in neuroscience is reconstructing synaptic connectivity in neural circuits. Synapses onto a neuron can be probed by sequentially stimulating potentially pre-synaptic neurons while monitoring the membrane voltage…

神经元与认知 · 定量生物学 2012-10-05 Tao Hu , Dmitri B. Chklovskii

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

神经元与认知 · 定量生物学 2020-10-06 Richard Betzel

There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the…

计算机视觉与模式识别 · 计算机科学 2015-05-19 Olaf Ronneberger , Philipp Fischer , Thomas Brox

Automated cell detection and localization from microscopy images are significant tasks in biomedical research and clinical practice. In this paper, we design a new cell detection and localization algorithm that combines deep convolutional…

计算机视觉与模式识别 · 计算机科学 2018-10-09 Yao Xue , Gilbert Bigras , Judith Hugh , Nilanjan Ray

Superconducting optoelectronic loop neurons are a class of circuits potentially conducive to networks for large-scale artificial cognition. These circuits employ superconducting components including single-photon detectors, Josephson…

神经与进化计算 · 计算机科学 2022-10-19 Jeffrey M. Shainline , Bryce A. Primavera , Saeed Khan

Understanding the mechanisms of neural communication in large-scale brain networks remains a major goal in neuroscience. We investigated whether navigation is a parsimonious routing model for connectomics. Navigating a network involves…

神经元与认知 · 定量生物学 2018-06-05 Caio Seguin , Martijn P. van den Heuvel , Andrew Zalesky

In the field of connectomics, neuroscientists seek to identify cortical connectivity comprehensively. Neuronal boundary detection from the Electron Microscopy (EM) images is often done to assist the automatic reconstruction of neuronal…

计算机视觉与模式识别 · 计算机科学 2017-08-01 Wei Shen , Bin Wang , Yuan Jiang , Yan Wang , Alan Yuille

The channel redundancy in feature maps of convolutional neural networks (CNNs) results in the large consumption of memories and computational resources. In this work, we design a novel Slim Convolution (SlimConv) module to boost the…

计算机视觉与模式识别 · 计算机科学 2021-09-08 Jiaxiong Qiu , Cai Chen , Shuaicheng Liu , Bing Zeng

In the field of Connectomics, a primary problem is that of 3D neuron segmentation. Although deep learning-based methods have achieved remarkable accuracy, errors still exist, especially in regions with image defects. One common type of…

计算机视觉与模式识别 · 计算机科学 2021-12-14 Jules Berman , Dmitri B. Chklovskii , Jingpeng Wu