相关论文: Relaxation-based viscosity mapping for magnetic pa…
Magnetic nanoparticles (MNPs) with proper surface functionalization have been extensively applied as labels for magnetic immunoassays, carriers for controlled drug/gene delivery, tracers and contrasts for magnetic imaging, etc. Here, we…
Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…
Magnetic nanoparticles play a crucial role in different fields such as biomedicine or information and quantum technologies. These applications require nanoparticles with a single, well-defined energy minimum, free of metastable states, and…
Magnetic Particle Imaging (MPI) is an emerging medical imaging modality that is not yet adopted by clinical practice. Most of the working MPI prototypes including commercial-grade research MPI scanners utilize cylindrical bores that limit…
A scalable mapping system for superconducting RF cavities is presented. Currently, it combines local temperature measurement with 3D magnetic field mapping along the outer surface of the resonator. This allows for the observation of dynamic…
In this work, we report a 5-minute magnetic particle spectroscopy (MPS)-based bioassay strategy. In our approach, surface functionalized magnetic nanoparticles (MNPs) are incubated with target analytes at 37 {\deg}C with agitation for 3…
Magnetic nanoparticle based hyperthermia emerged as a potential tool for treating malignant tumours. The efficiency of the method relies on the knowledge of magnetic properties of the samples; in particular, knowledge of the frequency…
Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…
Magnetic resonance imaging (MRI) is a powerful technique for investigating the microscopic properties and dynamics of physical systems. In this work we demonstrate state-sensitive MRI of ultracold atoms in an optical lattice. Single-shot…
We show that a single atomic magnetometer in a magnetically unshielded environment can be used to perform magnetic particle spectroscopy (MPS) and AC susceptometry (ACS) on liquid-suspended magnetic nanoparticles. We demonstrate methods…
This thesis reports advances in magnetic resonance imaging (MRI), with the ultimate goal of improving signal and contrast in biomedical applications. More specifically, novel MRI pulse sequences have been designed to characterize…
Microplastics (MPs) are ubiquitous in all ecosystems, affecting wildlife and, ultimately, human health. The complexity of natural samples plus the unspecificity of their treatments to isolate polymers renders the characterization of…
The purpose of this study was to develop a method for tissue elasticity imaging using tagged magnetic resonance imaging (MRI). First, we developed a cyclic pressure device that used air to remotely transmit the power to generate cyclic…
Objective: Magnetic particle imaging (MPI) is an emerging medical imaging modality which has gained increasing interest in recent years. Among the benefits of MPI are its high temporal resolution, and that the technique does not expose the…
While the multiexponential nature of T2 decays measured in vivo is well known, characterizing T2 decays by a single time constant is still very useful when differentiating among structures and pathologies in MRI images. A novel, robust,…
CT and MRI are the two most widely used imaging modalities in healthcare, each with its own merits and drawbacks. Combining these techniques in one machine could provide unprecedented resolution and sensitivity in a single scan, and serve…
Nanocomposites comprised of insulated magnetic single-domain particles are promising candidates for high-frequency, eddy current free, soft magnetic materials, but tend to suffer from low magnetic susceptibility ($<20$). Particle alignment…
Magnetic Particle Imaging (MPI) is a tomographic imaging modality capable of real-time, high-sensitivity mapping of superparamagnetic iron oxide nanoparticles. Model-based image reconstruction provides an alternative to conventional methods…
Reducing the scanning time of very-low field (VLF) magnetic resonance imaging (MRI) scanners, commonly employed for stroke diagnosis, can enhance patient comfort and operational efficiency. The conventional parallel imaging (PI) technique…
The field of nanoscale magnetic resonance imaging (NanoMRI) was started 30 years ago. It was motivated by the desire to image single molecules and molecular assemblies, such as proteins and virus particles, with near-atomic spatial…