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相关论文: Drug-Drug Interaction Extraction from Biomedical T…

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Long-term memory mechanisms enable Large Language Models (LLMs) to maintain continuity and personalization across extended interaction lifecycles, but they also introduce new and underexplored risks related to fairness. In this work, we…

机器学习 · 计算机科学 2026-02-03 Yiming Ma , Lixu Wang , Lionel Z. Wang , Hongkun Yang , Haoming Sun , Xin Xu , Jiaqi Wu , Bin Chen , Wei Dong

Natural language inference (NLI) is a fundamentally important task in natural language processing that has many applications. The recently released Stanford Natural Language Inference (SNLI) corpus has made it possible to develop and…

计算与语言 · 计算机科学 2016-11-11 Shuohang Wang , Jing Jiang

Identification of drug-target interactions is an indispensable part of drug discovery. While conventional shallow machine learning and recent deep learning methods based on chemogenomic properties of drugs and target proteins have pushed…

Recently, the impressive performance of large language models (LLMs) on a wide range of tasks has attracted an increasing number of attempts to apply LLMs in drug discovery. However, molecule optimization, a critical task in the drug…

定量方法 · 定量生物学 2024-01-22 Geyan Ye , Xibao Cai , Houtim Lai , Xing Wang , Junhong Huang , Longyue Wang , Wei Liu , Xiangxiang Zeng

Drug combination refers to the use of two or more drugs to treat a specific disease at the same time. It is currently the mainstream way to treat complex diseases. Compared with single drugs, drug combinations have better efficacy and can…

定量方法 · 定量生物学 2024-10-15 Xinxing Yang , Jiachen Li , Xiao Kang , Guojin Pei , Keyu Liu , Genke Yang , Jian Chu

Disease risk prediction has attracted increasing attention in the field of modern healthcare, especially with the latest advances in artificial intelligence (AI). Electronic health records (EHRs), which contain heterogeneous patient…

人工智能 · 计算机科学 2022-01-19 Shuai Niu , Qing Yin , Yunya Song , Yike Guo , Xian Yang

Drug target interaction (DTI) prediction is a cornerstone of computational drug discovery, enabling rational design, repurposing, and mechanistic insights. While deep learning has advanced DTI modeling, existing approaches primarily rely on…

机器学习 · 计算机科学 2025-11-05 Feng Jiang , Amina Mollaysa , Hehuan Ma , Tommaso Mansi , Junzhou Huang , Mangal Prakash , Rui Liao

miRNA mRNA relations are closely linked to several biological processes and disease mechanisms In a recent study we tested the performance of large language models LLMs on extracting miRNA mRNA relations from PubMed PubMedBERT achieved the…

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

图像与视频处理 · 电气工程与系统科学 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin

This paper develops a model that addresses sentence embedding, a hot topic in current natural language processing research, using recurrent neural networks with Long Short-Term Memory (LSTM) cells. Due to its ability to capture long term…

计算与语言 · 计算机科学 2016-11-18 Hamid Palangi , Li Deng , Yelong Shen , Jianfeng Gao , Xiaodong He , Jianshu Chen , Xinying Song , Rabab Ward

Biomedical knowledge is growing in an astounding pace with a majority of this knowledge is represented as scientific publications. Text mining tools and methods represents automatic approaches for extracting hidden patterns and trends from…

信息检索 · 计算机科学 2026-03-03 Balu Bhasuran , Gurusamy Murugesan , Jeyakumar Natarajan

Drug overdose remains a critical global health issue, often driven by misuse of opioids, painkillers, and psychiatric medications. Traditional research methods face limitations, whereas social media offers real-time insights into…

计算与语言 · 计算机科学 2025-07-16 Muhammad Ahmad , Fida Ullah , Muhammad Usman , Umyh Habiba , ldar Batyrshin , Grigori Sidorov

Computational methods are useful in accelerating the pace of drug discovery. Drug discovery carries several steps such as target identification and validation, lead discovery, and lead optimisation etc., In the phase of lead optimisation,…

机器学习 · 计算机科学 2024-08-31 K. Venkateswara Rao , Kunjam Nageswara Rao , G. Sita Ratnam

Due to the limitations in the accuracy and robustness of current electroencephalogram (EEG) classification algorithms, applying motor imagery (MI) for practical Brain-Computer Interface (BCI) applications remains challenging. This paper…

人机交互 · 计算机科学 2023-12-21 Shiwei Cheng , Yuejiang Hao

Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent…

机器学习 · 计算机科学 2022-09-01 Haifan zhou , Wenjing Zhou , Junfeng Wu

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

人机交互 · 计算机科学 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Monitoring the biomedical literature for cases of Adverse Drug Reactions (ADRs) is a critically important and time consuming task in pharmacovigilance. The development of computer assisted approaches to aid this process in different forms…

计算与语言 · 计算机科学 2018-04-25 Diego Saldana Miranda

There is a great need for technologies that can predict the mortality of patients in intensive care units with both high accuracy and accountability. We present joint end-to-end neural network architectures that combine long short-term…

计算与语言 · 计算机科学 2017-09-12 Yohan Jo , Lisa Lee , Shruti Palaskar

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…

声音 · 计算机科学 2026-02-09 Yifan Gao , Long Guo , Hong Liu

Past work in relation extraction has focused on binary relations in single sentences. Recent NLP inroads in high-value domains have sparked interest in the more general setting of extracting n-ary relations that span multiple sentences. In…

计算与语言 · 计算机科学 2017-08-15 Nanyun Peng , Hoifung Poon , Chris Quirk , Kristina Toutanova , Wen-tau Yih