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Inferring knowledge from clinical trials using knowledge graph embedding is an emerging area. However, customizing graph embeddings for different use cases remains a significant challenge. We propose custom2vec, an algorithmic framework to…

机器学习 · 计算机科学 2023-01-02 Xiong Liu , Iya Khalil , Murthy Devarakonda

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

机器学习 · 统计学 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

机器学习 · 计算机科学 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

As clinical data are becoming increasingly available, machine learning methods have been employed to extract knowledge from them and predict clinical events. While promising, approaches suffer from at least two main issues: low availability…

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

机器学习 · 计算机科学 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

计算与语言 · 计算机科学 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

Recently, Le and Mikolov (2014) proposed doc2vec as an extension to word2vec (Mikolov et al., 2013a) to learn document-level embeddings. Despite promising results in the original paper, others have struggled to reproduce those results. This…

计算与语言 · 计算机科学 2016-12-19 Jey Han Lau , Timothy Baldwin

We investigate whether temporal embedding models trained on longitudinal electronic health records can learn clinically meaningful representations without compromising predictive performance, and how architectural choices affect embedding…

机器学习 · 计算机科学 2026-04-17 Aditya Kumar , Mario A. Cypko , Oliver Amft

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

机器学习 · 计算机科学 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

In this work, we examine the extent to which embeddings may encode marginalized populations differently, and how this may lead to a perpetuation of biases and worsened performance on clinical tasks. We pretrain deep embedding models (BERT)…

计算与语言 · 计算机科学 2020-03-26 Haoran Zhang , Amy X. Lu , Mohamed Abdalla , Matthew McDermott , Marzyeh Ghassemi

Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from…

机器学习 · 计算机科学 2026-04-22 Lei Liu , Jialin Chen , Kathy Macropol

Intensive Care Units usually carry patients with a serious risk of mortality. Recent research has shown the ability of Machine Learning to indicate the patients' mortality risk and point physicians toward individuals with a heightened need…

机器学习 · 计算机科学 2025-02-03 Korbinian Randl , Núria Lladós Armengol , Lena Mondrejevski , Ioanna Miliou

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…

应用统计 · 统计学 2024-03-07 Giacomo Lancia , Meri Varkila , Olaf Cremer , Cristian Spitoni

Biomedical text embeddings have primarily been developed using research literature from PubMed, yet clinical cardiology practice relies heavily on procedural knowledge and specialized terminology found in comprehensive textbooks rather than…

计算与语言 · 计算机科学 2025-11-17 Richard J. Young , Alice M. Matthews

The International Classification of Diseases (ICD) is an authoritative medical classification system of different diseases and conditions for clinical and management purposes. ICD indexing assigns a subset of ICD codes to a medical record.…

计算与语言 · 计算机科学 2024-05-30 Xindi Wang , Robert E. Mercer , Frank Rudzicz

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

机器学习 · 计算机科学 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

The number of academic papers being published is increasing exponentially in recent years, and recommending adequate citations to assist researchers in writing papers is a non-trivial task. Conventional approaches may not be optimal, as the…

信息检索 · 计算机科学 2020-01-09 Yang Zhang , Qiang Ma

Early prediction of in-hospital mortality in critically ill patients can aid clinicians in optimizing treatment. The objective was to develop a multimodal deep learning model, using structured and unstructured clinical data, to predict…

机器学习 · 计算机科学 2025-12-24 Behrooz Mamandipoor , Chun-Nan Hsu , Martin Krause , Ulrich H. Schmidt , Rodney A. Gabriel