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Decoding complex relationships among large numbers of variables with relatively few observations is one of the crucial issues in science. One approach to this problem is Gaussian graphical modeling, which describes conditional independence…

统计方法学 · 统计学 2019-04-26 A. Mohammadi , E. C. Wit

Model-based approaches for (bio)process systems often suffer from incomplete knowledge of the underlying physical, chemical, or biological laws. Universal differential equations, which embed neural networks within differential equations,…

机器学习 · 统计学 2026-05-20 Arno Strouwen

Over the last decade, large-scale multiple testing has found itself at the forefront of modern data analysis. In many applications data are correlated, so that the observed test statistic used for detecting a non-null case, or signal, at…

统计方法学 · 统计学 2017-02-09 D. Andrew Brown , Gauri S. Datta , Nicole A. Lazar

Most successful applications of deep learning involve similar training and test conditions. However, tasks such as biological sequence design involve searching for sequences that improve desirable properties beyond previously known values,…

机器学习 · 计算机科学 2025-05-27 Sophia Hager , Aleem Khan , Andrew Wang , Nicholas Andrews

High-dimensional variable selection, with many more covariates than observations, is widely documented in standard regression models, but there are still few tools to address it in non-linear mixed-effects models where data are collected…

Bioacoustic recognition requires fine-grained acoustic understanding to distinguish similar-sounding species. However, many large-scale data repositories such as iNaturalist are weakly annotated, often with only a single positive species…

声音 · 计算机科学 2026-05-15 Wuao Liu , Mustafa Chasmai , Subhransu Maji , Grant Van Horn

We propose a Bayesian hidden Markov model for analyzing time series and sequential data where a special structure of the transition probability matrix is embedded to model explicit-duration semi-Markovian dynamics. Our formulation allows…

统计方法学 · 统计学 2022-05-23 Beniamino Hadj-Amar , Jack Jewson , Mark Fiecas

We focus on using the predictive uncertainty signal calculated by Bayesian neural networks to guide learning in the self-same task the model is being trained on. Not opting for costly Monte Carlo sampling of weights, we propagate the…

Animal learning has interested ecologists and psychologists for over a century. Mathematical models that explain how animals store and recall information have gained attention recently. Central to this work is statistical decision theory…

定量方法 · 定量生物学 2022-08-29 Peter R. Thompson , Melodie Kunegel-Lion , Mark A. Lewis

A method was developed for Bayesian inference of species phylogeny using the multi-species coalescent model. To improve the mixing properties of the Markov chain Monte Carlo (MCMC) algorithm that traverses the space of species trees, we…

种群与进化 · 定量生物学 2015-12-15 Bruce Rannala , Ziheng Yang

Machine learning strategies like multi-task learning, meta-learning, and transfer learning enable efficient adaptation of machine learning models to specific applications in healthcare, such as prediction of various diseases, by leveraging…

机器学习 · 计算机科学 2024-12-31 Sophie Wharrie , Lisa Eick , Lotta Mäkinen , Andrea Ganna , Samuel Kaski , FinnGen

Multivariate data sources with components of different information value seem to appear frequently in practice. Models in which the components change their homogeneity at different times are of significant importance. The fact whether any…

最优化与控制 · 数学 2020-11-04 Krzysztof Szajowski

The automatic classification of animal sounds presents an enduring challenge in bioacoustics, owing to the diverse statistical properties of sound signals, variations in recording equipment, and prevalent low Signal-to-Noise Ratio (SNR)…

声音 · 计算机科学 2024-07-08 Qiang Yang , Xiuying Chen , Changsheng Ma , Carlos M. Duarte , Xiangliang Zhang

Songs of many songbird species consist of variable sequences of a finite number of syllables. A common approach for characterizing the syntax of these complex syllable sequences is to use transition probabilities between the syllables. This…

神经元与认知 · 定量生物学 2013-08-22 Dezhe Z. Jin , Alexay A. Kozhevnikov

Neuronal ensemble inference is a significant problem in the study of biological neural networks. Various methods have been proposed for ensemble inference from experimental data of neuronal activity. Among them, Bayesian inference approach…

无序系统与神经网络 · 物理学 2021-06-03 Shun Kimura , Keisuke Ota , Koujin Takeda

We introduce a Bayesian framework for inference with a supervised version of the Gaussian process latent variable model. The framework overcomes the high correlations between latent variables and hyperparameters by using an unbiased pseudo…

机器学习 · 统计学 2018-03-29 Charles Gadd , Sara Wade , Akeel Shah , Dimitris Grammatopoulos

Progress in neuroscience has provided unprecedented opportunities to advance our understanding of brain alterations and their correspondence to phenotypic profiles. With data collected from various imaging techniques, studies have…

统计方法学 · 统计学 2024-08-01 Zhe Sun , Wanwan Xu , Tianxi Li , Jian Kang , Gregorio Alanis-Lobato , Yize Zhao

Character-level models of tokens have been shown to be effective at dealing with within-token noise and out-of-vocabulary words. But these models still rely on correct token boundaries. In this paper, we propose a novel end-to-end…

计算与语言 · 计算机科学 2020-01-03 Apostolos Kemos , Heike Adel , Hinrich Schütze

Passive acoustic monitoring offers a scalable, non-invasive method for tracking global biodiversity and anthropogenic impacts on species. Although deep learning has become a vital tool for processing this data, current models are…

机器学习 · 计算机科学 2023-08-10 David Robinson , Adelaide Robinson , Lily Akrapongpisak

It is of some interest to understand how statistically based mechanisms for signal processing might be integrated with biologically motivated mechanisms such as neural networks. This paper explores a novel hybrid approach for classifying…

神经与进化计算 · 计算机科学 2016-07-22 Amirhossein Tavanaei , Anthony S Maida