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Nowadays, magnetic hyperthermia constitutes a complementary approach to cancer treatment. The use of magnetic particles as heating mediators, proposed in the 1950s, provides a novel strategy for improving tumor treatment and, consequently,…

In the 21st century, new and alternative non-radioactive methods for cancer treatment have been developed. One of this is magnetic hyperthermia (MH), which is based on the ability of magnetic nanoparticles (MNP) to transduce electromagnetic…

医学物理 · 物理学 2020-07-28 Christian Calvache , Jenny Mera-Córdoba , Diego F. Coral

In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…

Magnetic fluid hyperthermia (MFH), the procedure of raising the temperature of tumor cells using magnetic nanoparticles (MNPs) as heating agents, has proven successful in treating some types of cancer. However, the low heating power…

There are several methods to improve cancer patient survival rates by inducing hyperthermia in tumor tissues, which involves raising their temperature above 41{\deg}C. These methods utilize different energy sources to deliver heat to the…

Magnetic particle hyperthermia, in which colloidal nanostructures are exposed to an alternating magnetic field, is a promising approach to cancer therapy. Unfortunately, the clinical efficacy of hyperthermia has not yet been optimized.…

Multimodal oncological strategies which combine chemotherapy or radiotherapy with hyperthermia have a potential of improving the efficacy of the non-surgical methods of cancer treatment. Hyperthermia engages the heat-shock response…

亚细胞过程 · 定量生物学 2013-09-05 Mikołaj Rybiński , Zuzanna Szymańska , Sławomir Lasota , Anna Gambin

Magnetic hyperthermia is an adjuvant therapy for cancer where injected magnetic nanoparticles are used to transfer energy from the time-dependent applied magnetic field into the surrounding medium. Its main importance is to be able to…

软凝聚态物质 · 物理学 2022-03-09 Zs. Iszaly , I. Gresits , I. G. Marian , Gy. Thuroczy , O. Sagi , B. G. Markus , F. Simon , I. Nandori

Magnetic hyperthermia with metallic nanoparticles is a therapeutic strategy that relies on heating cancer cells to levels sufficient to damage or destroy them. After injection, the nanoparticles accumulate in tumor tissues, where they…

软凝聚态物质 · 物理学 2026-03-19 Zs. Iszály , A. Husztek , B. Mehmeti , Z. Erdélyi , Á. Szöőr , M. Béres , J. Korózs , V. Bacsó , I. Nándori , I. G. Márián

Hyperthermia has been in use for many years; as a potential alternative modality for cancer treatment. In this paper, an experimental investigation of microwave assisted thermal heating (MWATH) of tissue phantom using a domestic microwave…

医学物理 · 物理学 2020-06-25 Dhiraj Kumar , Purbarun Dhar , Anup Paul

This study was undertaken to develop a system for heat transfer simulation for optimization and treatment planning of magnetic hyperthermia treatment (MHT) using magnetic particle imaging (MPI). First, we performed phantom experiments to…

医学物理 · 物理学 2016-05-27 Natsuo Banura , Atsushi Mimura , Kohei Nishimoto , Kenya Murase

Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

计算工程、金融与科学 · 计算机科学 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

Radiotherapy can effectively kill malignant cells, but the doses required to cure cancer patients may inflict severe collateral damage to adjacent healthy tissues. Hyperthermia (HT) is a promising option to improve the outcome of radiation…

Single-domain ferromagnetic nanoparticle systems can be used to transfer energy from a time-dependent magnetic field into their environment. This local heat generation, i.e., magnetic hyperthermia, receives applications in cancer therapy…

软凝聚态物质 · 物理学 2018-08-02 Zs. Iszaly , K. Lovasz , I. Nagy , I. G. Marian , J. Racz , I. A. Szabo , L. Toth , N. F. Vas , V. Vekony , I. Nandori

We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

组织与器官 · 定量生物学 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

Microwave hyperthermia aims at selectively heating cancer cells to a supra-physiological temperature. For non-superficial tumors, this can be achieved by means of an antenna array equipped with a proper cooling system (the water bolus) to…

计算工程、金融与科学 · 计算机科学 2020-12-15 Rossella Gaffoglio , Marco Righero , Giorgio Giordanengo , Marcello Zucchi , Giuseppe Vecchi

Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the…

介观与纳米尺度物理 · 物理学 2014-03-26 Daniel B. Reeves , John B. Weaver

The main idea of magnetic hyperthermia is to increase locally the temperature of the human body by means of injected superparamagnetic nanoparticles. They absorb energy from a time-dependent external magnetic field and transfer it into…

软凝聚态物质 · 物理学 2021-09-27 Zs. Iszaly , I. G. Marian , I. A. Szabo , A. Trombettoni , I. Nandori

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

医学物理 · 物理学 2020-07-29 Abhijit Paul , Anup Paul

Magnetic nanoparticle-based hyperthermia has emerged as a promising therapeutic modality for treating malignant solid tumors that exhibit resistance to conventional cancer treatments, including chemotherapy and radiation. Despite the…

介观与纳米尺度物理 · 物理学 2024-08-21 S. Scheibler , H. Wei , J. Ackers , S. Helbig , S. Koraltan , R. Peremadathil-Pradeep , M. Krupiński , M. Graeser , D. Suess , I. K. Herrmann , H. J. Hug
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