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Many practical decision-making problems in economics and healthcare seek to estimate the average treatment effect (ATE) from observational data. The Double/Debiased Machine Learning (DML) is one of the prevalent methods to estimate ATE in…

计量经济学 · 经济学 2022-12-07 Yiyan Huang , Cheuk Hang Leung , Xing Yan , Qi Wu , Shumin Ma , Zhiri Yuan , Dongdong Wang , Zhixiang Huang

Anatomical changes during intensity-modulated proton therapy (IMPT) for head-and-neck cancer (HNC) can shift Bragg peaks, risking tumor underdosing and organ-at-risk overdosing. Treatment replanning is often required to maintain clinically…

医学物理 · 物理学 2025-08-13 Malvern Madondo , Yuan Shao , Yingzi Liu , Jun Zhou , Xiaofeng Yang , Zhen Tian

Precision medicine aims to tailor therapeutic decisions to individual patient characteristics. This objective is commonly formalized through dynamic treatment regimes, which use statistical and machine learning methods to derive sequential…

机器学习 · 统计学 2026-03-23 Sophia Yazzourh , Erica E. M. Moodie

Multimodal learning often encounters the under-optimized problem and may perform worse than unimodal learning. Existing approaches attribute this issue to imbalanced learning across modalities and tend to address it through gradient…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Shicai Wei , Chunbo Luo , Yang Luo

Individualized treatment regimes (ITRs) aim to improve clinical outcomes by assigning treatment based on patient-specific characteristics. However, existing methods often struggle with high-dimensional covariates, limiting accuracy,…

机器学习 · 统计学 2026-01-13 Sungtaek Son , Eardi Lila , Kwun Chuen Gary Chan

Dynamic treatment regimes are sequential decision rules that adapt treatment according to individual time-varying characteristics and outcomes to achieve optimal effects, with applications in precision medicine, personalized…

统计方法学 · 统计学 2025-10-24 Yuanshan Gao , Yang Bai , Yifan Cui

The type of decision dependent uncertainties (DDUs) imposes a great challenge in decision making, while existing methodologies are not sufficient to support many real practices. In this paper, we present a systematic study to handle this…

最优化与控制 · 数学 2022-03-31 Bo Zeng , Wei Wang

Post-training with Reinforcement Learning (RL) has substantially improved reasoning in Large Language Models (LLMs) via test-time scaling. However, extending this paradigm to Multimodal LLMs (MLLMs) through verbose rationales yields limited…

计算与语言 · 计算机科学 2026-02-16 Bangzheng Li , Jianmo Ni , Chen Qu , Ian Miao , Liu Yang , Xingyu Fu , Muhao Chen , Derek Zhiyuan Cheng

Existing modular Reinforcement Learning (RL) architectures are generally based on reusable components, also allowing for "plug-and-play" integration. However, these modules are homogeneous in nature - in fact, they essentially provide…

机器学习 · 计算机科学 2024-11-01 Lorenz Wolf , Mirco Musolesi

The continually increasing number of complex datasets each year necessitates ever improving machine learning methods for robust and accurate categorization of these data. This paper introduces Random Multimodel Deep Learning (RMDL): a new…

机器学习 · 计算机科学 2018-06-01 Kamran Kowsari , Mojtaba Heidarysafa , Donald E. Brown , Kiana Jafari Meimandi , Laura E. Barnes

With the development of deep learning, Dynamic Portfolio Optimization (DPO) problem has received a lot of attention in recent years, not only in the field of finance but also in the field of deep learning. Some advanced research in recent…

计算工程、金融与科学 · 计算机科学 2025-01-16 Runsheng Lin , Zihan Xing , Mingze Ma , Raymond S. T. Lee

Medical research, particularly in predicting patient outcomes, heavily relies on medical time series data extracted from Electronic Health Records (EHR), which provide extensive information on patient histories. Despite rigorous…

机器学习 · 计算机科学 2025-06-04 Yuhao Li , Ling Luo , Uwe Aickelin

Deep reinforcement learning (DRL) algorithms can suffer from modeling errors between the simulation and the real world. Many studies use adversarial learning to generate perturbation during training process to model the discrepancy and…

机器学习 · 计算机科学 2024-05-21 Qianmei Liu , Yufei Kuang , Jie Wang

Two-stage adaptive robust optimization (ARO) is a powerful approach for planning under uncertainty, balancing first-stage decisions with recourse decisions made after uncertainty is realized. To account for uncertainty, modelers typically…

系统与控制 · 电气工程与系统科学 2025-04-10 Aron Brenner , Rahman Khorramfar , Jennifer Sun , Saurabh Amin

Limiting failures of machine learning systems is of paramount importance for safety-critical applications. In order to improve the robustness of machine learning systems, Distributionally Robust Optimization (DRO) has been proposed as a…

A diversified risk-adjusted time-series momentum (TSMOM) portfolio can deliver substantial abnormal returns and offer some degree of tail risk protection during extreme market events. The performance of existing TSMOM strategies, however,…

计算金融 · 定量金融 2023-06-29 Joel Ong , Dorien Herremans

This paper presents a novel neural network training approach for faster convergence and better generalization abilities in deep reinforcement learning. Particularly, we focus on the enhancement of training and evaluation performance in…

机器学习 · 计算机科学 2020-05-26 Mohammed Sharafath Abdul Hameed , Gavneet Singh Chadha , Andreas Schwung , Steven X. Ding

Distribution shifts and minority subpopulations frequently undermine the reliability of deep neural networks trained using Empirical Risk Minimization (ERM). Distributionally Robust Optimization (DRO) addresses this by optimizing for the…

机器学习 · 计算机科学 2025-11-11 Aheer Sravon , Devdyuti Mazumder , Md. Ibrahim

An individualized decision rule (IDR) is a decision function that assigns each individual a given treatment based on his/her observed characteristics. Most of the existing works in the literature consider settings with binary or finitely…

统计方法学 · 统计学 2023-01-31 Hengrui Cai , Chengchun Shi , Rui Song , Wenbin Lu

This study presents a comparative analysis between single-objective and multi-objective reinforcement learning methods for training a robot to navigate effectively to an end goal while efficiently avoiding obstacles. Traditional…

机器人学 · 计算机科学 2023-12-15 Vicki Young , Jumman Hossain , Nirmalya Roy