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Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…

Fluorescent nuclear track detectors (FNTDs) based on Al2O3:C,Mg single crystal combined with confocal microscopy provide 3D information on ion tracks with a resolution only limited by light diffraction. FNTDs are also ideal substrates to be…

Carbon ion therapy have the ability to overcome the limitation of convertional radiotherapy due to its most energy deposition in selective depth, usually called Bragg peak, which results in increased biological effectiness. During carbon…

Purpose: This is a theoretical simulation study for proof of concept of radiochromic film dosimetry to measure physical and biological doses without plan-based quenching correction for patient-specific quality assurance of carbon-ion…

医学物理 · 物理学 2019-03-25 Nobuyuki Kanematsu , Taku Inaniwa , Shunsuke Yonai , Hideyuki Mizuno

The recent application of Fourier Based Iterative Reconstruction Method (FIRM) has made it possible to achieve high-quality 2D images from a fan beam Computed Tomography (CT) scan with a limited number of projections in a fast manner. The…

图像与视频处理 · 电气工程与系统科学 2020-06-24 N. Teyfouri , H. Rabbani , R. Kafieh , Iraj Jabbari

Radiation therapy with carbon ions is a novel technique of cancer radiotherapy, applicable in particular to treating radioresistant tumours at difficult localisations. Therapy planning, where the medical physicist, following the medical…

医学物理 · 物理学 2014-10-07 Leszek Grzanka

The VAMOS++ magnetic spectrometer is characterized by a large angular and momentum acceptance and highly non-linear ion optics properties requiring the use of software ion trajectory reconstruction methods to measure the ion magnetic…

仪器与探测器 · 物理学 2025-04-01 M. Rejmund , A. Lemasson

Cone-beam CT (CBCT) has been widely used in image guided radiation therapy (IGRT) to acquire updated volumetric anatomical information before treatment fractions for accurate patient alignment purpose. However, the excessive x-ray imaging…

医学物理 · 物理学 2010-04-13 Xun Jia , Yifei Lou , John Lewis , Ruijiang Li , Xuejun Gu , Chunhua Men , William Y. Song , Steve B. Jiang

We propose a method to achieve the geometric calibration of cone-beam imaging and delivery systems in radiation therapy; our approach applies to devices where an X-ray source and a flat-panel detector, facing each other, move in circular…

医学物理 · 物理学 2007-05-23 Evangelos Matsinos , Wolfgang Kaissl

The purpose of this work is to provide a fast and accurate scatter artifacts correction algorithm for cone beam CT (CBCT) imaging. The method starts with an estimation of coarse scatter profiles for a set of CBCT data in either image domain…

医学物理 · 物理学 2016-04-27 Wei Zhao , Don Vernekohl , Jun Zhu , Luyao Wang , Lei Xing

At the Heidelberg Ion-Beam Therapy Center, the track structure of carbon ions of therapeutic energy after penetrating layers of simulated tissue was investigated for the first time. Measurements were conducted with carbon ion beams of…

医学物理 · 物理学 2025-10-20 Gerhard Hilgers , Miriam Schwarze , Hans Rabus

A prototype plastic scintillating fibre based beam profile monitor was tested at the Heidelberg Ion Therapy Centre / \textit{Heidelberg Ionenstrahl Therapiezentrum} (HIT) in 2016 to determine its beam property reconstruction performance and…

仪器与探测器 · 物理学 2018-06-27 B. D. Leverington , M. Dziewiecki , L. Renner , R. Runze

In dental cone-beam computed tomography (CBCT), compact and cost-effective system designs often use small detectors, resulting in a truncated field of view (FOV) that does not fully encompass the patient's head. In iterative reconstruction…

计算机视觉与模式识别 · 计算机科学 2025-08-12 Hyoung Suk Park , Kiwan Jeon

Carbon ion therapy is one of the most advanced forms of radiotherapy, promising improved efficacy against resistant cancers. However, the high precision offered by the carbon ion Bragg peak requires precise knowledge of the beam range…

Iterative methods for tomographic image reconstruction have great potential for enabling high quality imaging from low-dose projection data. The computational burden of iterative reconstruction algorithms, however, has been an impediment in…

图像与视频处理 · 电气工程与系统科学 2019-07-25 Kai Zhang , Alireza Entezari

We solve the orientation recovery of a tumbling protein in the gas phase from single-event measurements of the spatial positions of its ions after an X-ray laser induced explosion. We simulate diffracted X-ray signal and ion dynamics under…

化学物理 · 物理学 2026-03-26 Tomas André , Alfredo Bellisario , Nicusor Timneanu , Carl Caleman

Interaction Vertex Imaging (IVI) is used for range monitoring (RM) in carbon ion radiotherapy. The purpose of RM is to measure the Bragg peak (BP) position for each contributing beam, and detect any changes. Currently, there is no consensus…

Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation…

We develop a novel algorithm for large-scale holographic reconstruction of 3D particle fields. Our method is based on a multiple-scattering beam propagation method (BPM) combined with sparse regularization that enables recovering dense 3D…

光学 · 物理学 2021-05-24 Hao Wang , Waleed Tahir , Jiabei Zhu , Lei Tian

Limited view tomographic reconstruction aims to reconstruct a tomographic image from a limited number of sinogram or projection views arising from sparse view or limited angle acquisitions that reduce radiation dose or shorten scanning…

图像与视频处理 · 电气工程与系统科学 2020-09-04 Bo Zhou , S. Kevin Zhou , James S. Duncan , Chi Liu
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