相关论文: On the Centrality of the Focus in Human Epileptic …

Purpose: Research into epileptic networks has recently allowed deeper insights into the epileptic process. Here we investigated the importance of individual network nodes for seizure dynamics. Methods: We analysed intracranial…

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

In many realistic networks, the edges representing the interactions between the nodes are time-varying. There is growing evidence that the complex network that models the dynamics of the human brain has time-varying interconnections, i.e.,…

Drug-resistant epilepsy is traditionally characterized by pathologic cortical tissue comprised of seizure-initiating `foci'. These `foci' are thought to be embedded within an epileptic network whose functional architecture dynamically…

Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of…

We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

The brain is a high-dimensional directional network system consisting of many regions as network nodes that influence each other. The directional influence from one region to another is referred to as directional connectivity. Epilepsy is a…

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

We consider the electrical signals recorded from a subdural array of electrodes placed on the pial surface of the brain for chronic evaluation of epileptic patients before surgical resection. A simple and computationally fast method to…

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

Epilepsy is one of the most serious neurological diseases, affecting 1-2% of the world's population. The diagnosis of epilepsy depends heavily on the recognition of epileptic waves, i.e., disordered electrical brainwave activity in the…

Pathological hubs in the brain networks of epilepsy patients are hypothesized to drive seizure generation and propagation. In epilepsy-surgery patients, these hubs have traditionally been associated with the resection area (RA): the region…

Epilepsy is one of the most common neurological disorders that greatly impair patient' daily lives. Traditional epileptic diagnosis relies on tedious visual screening by neurologists from lengthy EEG recording that requires the presence of…

Epileptic seizures are considered as abnormally hypersynchronous neuronal activities of the brain. Do hypersynchronous neuronal activities in a brain region lead to seizure or the hypersynchronous activities take place due to the…

The electroencephalographic (EEG) data intracerebrally recorded from 20 epileptic humans with different brain origins of focal epilepsies or types of seizures, ages and sexes are investigated (nearly 700 million data). Multi channel…

Cortical network functioning critically depends on finely tuned interactions to afford neuronal activity propagation over long distances while avoiding runaway excitation. This importance is highlighted by the pathological consequences and…

Epilepsy is a network disease. The epileptic network usually involves spatially distributed brain regions. In this context, noninvasive M/EEG source connectivity is an emerging technique to identify functional brain networks at cortical…

Epilepsy creates a persistent increase in the probability of spontaneous seizures. An ictal episode evolves due to acute disturbance of the fine-tuned balance between excitatory vs. inhibitory inputs within a neural network in favor of…