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Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…

生物物理 · 物理学 2024-11-26 Jie Liao , Maxwell Adolphson , Hangyue Li , Dipayon Kumar Sikder , Chenyang Lu , Lan Yang

Operation of nanomechanical devices in water environment has been challenging due to the strong viscous damping that greatly impedes the mechanical motion. Here we demonstrate an optomechanical micro-wheel resonator integrated in…

光学 · 物理学 2015-08-12 King Yan Fong , Menno Poot , Hong X. Tang

Tracking the evolution of an individual nanodroplet of liquid in real-time remains an outstanding challenge. Here a miniature optomechanical resonator detects a single nanodroplet landing on a surface and measures its subsequent evaporation…

流体动力学 · 物理学 2022-11-23 Samantha Sbarra , Louis Waquier , Stephan Suffit , Aristide Lemaître , Ivan Favero

We demonstrate multimode optomechanical sensing of individual nanoparticles with radius of a hundred of nanometers. A semiconductor optomechanical disk resonator is optically driven and detected under ambient conditions, as nebulized…

High-throughput label-free measurements of the optical and mechanical properties of single microparticles play an important role in biological research, drug development, and related large population assays. Mechanical detection techniques…

仪器与探测器 · 物理学 2018-12-05 Kewen Han , Jeewon Suh , Gaurav Bahl

Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

定量方法 · 定量生物学 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

The recent development of opto-mechano-fluidic resonators has provided -- by harnessing photon radiation pressure -- a new microfluidics platform for the optical sensing of fluid density and bulk modulus. Here we show that fluid viscosity…

光学 · 物理学 2014-07-15 Kewen Han , Kaiyuan Zhu , Gaurav Bahl

Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

We propose and demonstrate a novel scheme for optical nanoparticle characterization, optofluidic force induction (OF2i), which achieves real-time optical counting with single-particle sensitivity, high throughput, and for particle sizes…

Vibrating nano- and micromechanical resonators have been the subject of research aiming at ultrasensitive mass sensors for mass spectrometry, chemical analysis and biomedical diagnosis. Unfortunately, their merits diminish dramatically in…

仪器与探测器 · 物理学 2015-09-30 E. Gil-Santos , C. Baker , D. T. Nguyen , W. Hease , A. Lemaître , S. Ducci , G. Leo , I. Favero

We report on a novel flow-based method for high-precision chemical detection that integrates quantum sensing with droplet microfluidics. We deploy nanodiamond particles hosting fluorescent nitrogen vacancy defects as quantum sensors in…

Many optical measurement techniques, such as light scattering from wavelength-scale particles or detecting motion from a surface with an optical lever, encode information in a complex radiation pattern. Extracting all available information…

量子物理 · 物理学 2025-12-22 Youssef Tawfik , Shan Hao , Thomas P. Purdy

Low-loss transmission and sensitive recovery of weak radio-frequency (rf) and microwave signals is an ubiquitous technological challenge, crucial in fields as diverse as radio astronomy, medical imaging, navigation and communication,…

Micro-mechanical resonators are widely used in modern sensing technology due to their high quality-factor (Q), enabling sensitive detection of various stimuli. However, the performance of these resonators in fluid environments is limited by…

仪器与探测器 · 物理学 2023-12-11 Sri Harsha Paladugu , Kaustav Roy , Anuj Ashok , Bibhas Nayak , Annapoorni Rangarajan , Rudra Pratap

The microfluidic optomechanical resonator (uFOMR) based on a thin-walled glass capillary supports high Q-factor (>1000) mechanical modes in the presence of liquids. In this Letter, the sensitivity of the uFOMR to the surface change is…

光学 · 物理学 2015-09-01 Kyu Hyun Kim , Xudong Fan

Cavity optomechanics provides high-performance sensor technology, and the scheme is also applicable to liquid samples for biological and rheological applications. However, previously reported methods using fluidic capillary channels and…

光学 · 物理学 2023-02-06 Motoki Asano , Hiroshi Yamaguchi , Hajime Okamoto

Ultrasensitive optical detection of nanometer-scaled particles is highly desirable for applications in early-stage diagnosis of human diseases, environmental monitoring, and homeland security, but remains extremely difficult due to ultralow…

Opto-mechano-fluidic resonators (OMFRs) are a unique optofluidics platform that can measure the acoustic properties of fluids and bioanalytes in a fully-contained microfluidic system. By confining light in ultra-high-Q whispering gallery…

光学 · 物理学 2014-05-22 Kaiyuan Zhu , Kewen Han , Tal Carmon , Xudong Fan , Gaurav Bahl

Optofluidics is dedicated to achieving integrated control of particle and fluid motion, particularly on the micrometer scale, by utilizing light to direct fluid flow and particle motion. The field has seen significant growth recently,…

Nanoelectromechanical resonators have been successfully used for a variety of sensing applications. Their extreme resolution comes from their small size at the cost of low capture area, making the "needle in a haystack" issue acute. This…

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