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Structure-based drug design (SBDD) aims to discover drug candidates by finding molecules (ligands) that bind tightly to a disease-related protein (targets), which is the primary approach to computer-aided drug discovery. Recently, applying…

定量方法 · 定量生物学 2022-12-01 Tianfan Fu , Wenhao Gao , Connor W. Coley , Jimeng Sun

Evolutionary Algorithms (EAs) are often challenging to apply in real-world settings since evolutionary computations involve a large number of evaluations of a typically expensive fitness function. For example, an evaluation could involve…

神经与进化计算 · 计算机科学 2024-04-08 Mohammed Ghaith Altarabichi , Sławomir Nowaczyk , Sepideh Pashami , Peyman Sheikholharam Mashhadi

In this paper we present several architectural and optimization recipes for generative adversarial network(GAN) based facial semantic inpainting. Current benchmark models are susceptible to initial solutions of non-convex optimization…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Avisek Lahiri , Arnav Jain , Divyasri Nadendla , Prabir Kumar Biswas

The performance of generative adversarial networks (GANs) heavily deteriorates given a limited amount of training data. This is mainly because the discriminator is memorizing the exact training set. To combat it, we propose Differentiable…

计算机视觉与模式识别 · 计算机科学 2020-12-08 Shengyu Zhao , Zhijian Liu , Ji Lin , Jun-Yan Zhu , Song Han

The increasing reliance on large-scale datasets in machine learning poses significant privacy and ethical challenges, particularly in sensitive domains such as face recognition. Synthetic data generation offers a promising alternative;…

计算机视觉与模式识别 · 计算机科学 2025-10-27 Parsa Rahimi , Damien Teney , Sebastien Marcel

Recently, Factorization Machines (FM) has become more and more popular for recommendation systems, due to its effectiveness in finding informative interactions between features. Usually, the weights for the interactions is learnt as a low…

机器学习 · 计算机科学 2018-04-18 Longfei Li , Peilin Zhao , Jun Zhou , Xiaolong Li

A bottleneck in any evolutionary art system is aesthetic evaluation. Many different methods have been proposed to automate the evaluation of aesthetics, including measures of symmetry, coherence, complexity, contrast and grouping. The…

神经与进化计算 · 计算机科学 2020-04-16 Jon McCormack , Andy Lomas

Object Detection has been a significant topic in computer vision. As the continuous development of Deep Learning, many advanced academic and industrial outcomes are established on localising and classifying the target objects, such as…

计算机视觉与模式识别 · 计算机科学 2019-07-31 Yingwei Zhou

Learning feature representation from discriminative local regions plays a key role in fine-grained visual classification. Employing attention mechanisms to extract part features has become a trend. However, there are two major limitations…

计算机视觉与模式识别 · 计算机科学 2021-05-06 Jianwei Song , Ruoyu Yang

We present a new approach for face recognition system. The method is based on 2D face image features using subset of non-correlated and Orthogonal Gabor Filters instead of using the whole Gabor Filter Bank, then compressing the output…

计算机视觉与模式识别 · 计算机科学 2015-03-13 Samir F. Hafez , Mazen M. Selim , Hala H. Zayed

This Generalized Discriminant Analysis (GDA) has provided an extremely powerful approach to extracting non linear features. The network traffic data provided for the design of intrusion detection system always are large with ineffective…

密码学与安全 · 计算机科学 2009-11-05 Shailendra Singh , Sanjay Silakari

Human gaze provides valuable information on human focus and intentions, making it a crucial area of research. Recently, deep learning has revolutionized appearance-based gaze estimation. However, due to the unique features of gaze…

计算机视觉与模式识别 · 计算机科学 2024-04-25 Yihua Cheng , Haofei Wang , Yiwei Bao , Feng Lu

Recently, feature selection has become an increasingly important area of research due to the surge in high-dimensional datasets in all areas of modern life. A plethora of feature selection algorithms have been proposed, but it is difficult…

神经与进化计算 · 计算机科学 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

Molecular discovery has brought great benefits to the chemical industry. Various molecule design techniques are developed to identify molecules with desirable properties. Traditional optimization methods, such as genetic algorithms,…

生物大分子 · 定量生物学 2025-11-05 Chris Zhuang , Debadyuti Mukherjee , Yingzhou Lu , Tianfan Fu , Ruqi Zhang

While deep face recognition models have demonstrated remarkable performance, they often struggle on the inputs from domains beyond their training data. Recent attempts aim to expand the training set by relying on computationally expensive…

计算机视觉与模式识别 · 计算机科学 2024-08-15 Mohammad Saeed Ebrahimi Saadabadi , Sahar Rahimi Malakshan , Seyed Rasoul Hosseini , Nasser M. Nasrabadi

Natural gradient has been recently introduced to the field of boosting to enable the generic probabilistic predication capability. Natural gradient boosting shows promising performance improvements on small datasets due to better training…

机器学习 · 计算机科学 2019-12-06 Liliang Ren , Gen Sun , Jiaman Wu

Enlarging input images is a straightforward and effective approach to promote small object detection. However, simple image enlargement is significantly expensive on both computations and GPU memory. In fact, small objects are usually…

计算机视觉与模式识别 · 计算机科学 2024-12-18 Kai Liu , Zhihang Fu , Sheng Jin , Ze Chen , Fan Zhou , Rongxin Jiang , Yaowu Chen , Jieping Ye

We investigate a biologically motivated approach to fast visual classification, directly inspired by the recent work of Serre et al. Specifically, trading-off biological accuracy for computational efficiency, we explore using wavelet and…

计算机视觉与模式识别 · 计算机科学 2008-06-10 Guoshen Yu , Jean-Jacques Slotine

In this paper, we propose in our novel generative framework the use of Generative Adversarial Networks (GANs) to generate features that provide robustness for object detection on reduced quality images. The proposed GAN-based Detection of…

计算机视觉与模式识别 · 计算机科学 2022-08-10 Charan D. Prakash , Lina J. Karam

We present BEAMER: a new spatially exploitative approach to learning object detectors which shows excellent results when applied to the task of detecting objects in greyscale aerial imagery in the presence of ambiguous and noisy data. There…

计算机视觉与模式识别 · 计算机科学 2009-07-27 Damian Eads , Edward Rosten , David Helmbold
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