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Many therapeutic advantages such as prolonged circulation in the blood, increased tumor drug uptake, enhanced therapeutic efficacy, and markedly reduced toxic side effects are provided by a carbon nanotube based chemotherapeutic…

Doxorubicin (DOX) is one of the most efficient antitumor drugs employed in numerous cancer therapies. Its incorporation into lipid-based nanocarriers, such as liposomes, improves the drug targeting into tumor cells and reduces drug side…

软凝聚态物质 · 物理学 2021-09-07 Paulo Siani , Edoardo Donadoni , Lorenzo Ferraro , Francesca Re , Cristiana Di Valentin

Monomolecular drug carriers based on calix[n]-arenes and -resorcinarenes containing the interior cavity can enhance the affinity and specificity of the osteoporosis inhibitor drug zoledronate (ZOD). In this work we investigate the…

化学物理 · 物理学 2018-02-14 Yong-Man Jang , Chol-Jun Yu , Jin-Song Kim , Song-Un Kim

Molecular communications is a promising framework for the design of controlled-release drug delivery systems. Under this framework, drug carriers, diseased cells, and the channel are modeled as transmitters, absorbing receivers, and…

Carefully designed micro and nanocarriers can provide significant advantages over conventional macroscopic counterparts in biomedical applications. The set of requirements including a high loading capacity, triggered release mechanisms,…

Temperature-responsive polymeric micelles have great potential in drug delivery, enhancing therapeutic efficacy while minimizing systemic toxicity. This study investigates the self-assembly of poly(ethylene…

医学物理 · 物理学 2025-08-20 Ghazal Jamirad , Mahdi Seif , Abbas Montazeri

The use of bacteria has been attractive to cancer researchers as drug delivery vehicle because motile bacteria are able to penetrate in tumors. In particular, the combination of therapeutic bacteria and conventional chemotherapy leads to…

组织与器官 · 定量生物学 2020-01-06 Hiroaki Shirai , Kosuke Tsukada

The interplay between lattice distortions and charge carriers governs the properties of many functional oxides. In alkali-doped LiMgPO4, a significant enhancement in dosimetric response is observed, but its microscopic origin is not…

材料科学 · 物理学 2025-12-03 Zhihua Zheng , Xiaolong Yao , Cailian Yu , Menghao Gao , Fangping Ouyang , Shiwu Gao

The first examples of single crystal epitaxial thin films of a high entropy perovskite oxide are synthesized. Pulsed laser deposition is used to grow the configurationally disordered ABO3 perovskite, Ba(Zr0.2Sn0.2Ti0.2Hf0.2Nb0.2)O3,…

Local configurational disorder can have a dominating role in the formation of macroscopic functional responses in strongly correlated materials. Here, we use entropy-stabilization synthesis to create single crystal epitaxial ABO3 perovskite…

A novel multifunctional nanodevice based in doxorubicin (DOX)- loaded mesoporous silica nanoparticles (MSNs) as nanoplatforms for the assembly of different building blocks has been developed for bone cancer treatment. These building blocks…

组织与器官 · 定量生物学 2021-03-19 M. Martinez-Carmona , D. Lozano , M. Colilla , M. Vallet-Regi

Ce(O,F)Sb(S,Se)2 single crystals were successfully grown using a CsCl/KCl flux method. The obtained crystals have a plate-like shape with the typical size of 1-2 mm and well-developed ab-plane, which enables X-ray single crystal structural…

Hydrophobically modified magnetic nanoparticles (MNPs) were encapsulated within the membrane of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA) block copolymer vesicles using a nanoprecipitation process. This formulation…

Calcium oxalate crystals are the most common biominerals found in plants. They also make their presence known as painful kidney stones in humans and animals. Their function in plants is extraordinarily versatile and encompasses calcium…

医学物理 · 物理学 2020-02-17 Eva Weber , Davide Levy , Matanya Ben Sasson , Andy N. Fitch , Boaz Pokroy

Development of the next generations of cancer therapy modalities is currently a crucial requirement of oncology. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are…

医学物理 · 物理学 2019-11-14 Enrico Catalano

We use solid-state methods to synthesize single crystals of perovskite-phase cesium lead iodide (${\gamma}$-CsPbI3) that are kinetically stable at room temperature. Single crystal X-ray diffraction characterization shows that the compound…

应用物理 · 物理学 2019-07-10 Daniel B. Straus , Shu Guo , Robert J. Cava

Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…

生物物理 · 物理学 2015-06-04 Guosong Hong , Justin Z. Wu , Joshua T. Robinson , Hailiang Wang , Bo Zhang , Hongjie Dai

Drug delivery systems represent a promising strategy to treat cancer and to overcome the side effects of chemotherapy. In particular, polymeric nanocontainers have attracted major interest because of their structural and morphological…

医学物理 · 物理学 2020-01-10 G. Pontrelli , G. Toniolo , S. McGinty , D. Peri , S. Succi , C. Chatgilialoglu

Semiconductor heterostructures that combine components with different dimensionality provide an interesting way to manipulate the physical properties of the resulting material. Two-dimensional lead halide perovskites crystallize as flat…

In this Letter we report the investigation of transport and static properties of a Bose-Einstein condensate in a large-spaced optical lattice. The lattice spacing can be easily tuned starting from few micrometers by adjusting the relative…

其他凝聚态物理 · 物理学 2009-11-11 Leonardo Fallani , Chiara Fort , Jessica Lye , Massimo Inguscio
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