相关论文: A hierarchical neural stimulation model for pain r…

Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited long-term success, as their…

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Despite recent advances in brain research, understanding the various signals for pain and pain intensities in the brain cortex is still a complex task due to temporal and spatial variations of brain hemodynamics. In this paper we have…

Neurostimulation using weak electric fields has generated excitement in recent years due to its potential as a medical intervention. However, study of this stimulation modality has been hampered by inconsistent results and large variability…

Nerve stimulation via micro-electrode implants is one of the neurostimulation approaches which is used frequently in the medical treatment of some brain disorders, neural prosthetics, brain-machine interfaces and also in the cyborg. In this…

In this article, we study optimal control problems of spiking neurons whose dynamics are described by a phase model. We design minimum-power current stimuli (controls) that lead to targeted spiking times of neurons, where the cases with…

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Neurostimulation is a promising therapy for abating epileptic seizures. However, it is extremely difficult to identify optimal stimulation patterns experimentally. In this study human recordings are used to develop a functional 24 neuron…

Magnetic stimulation is a standard tool in brain research and many fields of neurology, as well as psychiatry. From a physical perspective, one key aspect of this method is the inefficiency of available setups. Whereas the spatial field…

Mental disorders may exhibit pathological brain rhythms and neurostimulation promises to alleviate of patients' symptoms by modifying these rhythms. Today, most neurostimulation schemes are open-loop, i.e. administer experimental…

Background: Calculation of the electric field induced by transcranial magnetic stimulation (TMS) in the brain requires accurate models of the stimulation coils. Reconstructing models from the measured magnetic fields of coils so far worked…

The sensory-triggered activity of a neuron is typically characterized in terms of a tuning curve, which describes the neuron's average response as a function of a parameter that characterizes a physical stimulus. What determines the shapes…

The behaviour of neurons under the influence of periodic external input has been modelled very successfully by circle maps. The aim of this note is to extend certain aspects of this analysis to a much more general class of forcing…

Cortical slow oscillations occur in the mammalian brain during deep sleep and have been shown to contribute to memory consolidation, an effect that can be enhanced by electrical stimulation. As the precise underlying working mechanisms are…

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Neuronal firing activities have attracted a lot of attention since a large population of spatiotemporal patterns in the brain is the basis for adaptive behavior and can also reveal the signs for various neurological disorders including…

The neural coding is yet to be discovered. The neuronal operational modes that arise with fixed inputs but with varying degrees of stimulation help to elucidate their coding properties. In neurons receiving {\it in vivo} stimulation, we…

The dynamical responses of complex neuronal networks to external stimulus injected on a \emph{single} neuron are investigated. Stimulating the largest-degree neuron in the network, it is found that as the intensity of the stimulus…

Spinal cord stimulation (SCS) is a therapeutic approach used for the management of chronic pain. It involves the delivery of electrical impulses to the spinal cord via an implanted device, which when given suitable stimulus parameters can…

Neural encoding is a field in neuroscience that focuses on characterizing how information from stimuli is encoded in the spiking activity of neurons. When more than one stimulus is present, a theory known as multiplexing posits that neurons…