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Survival Analysis (SA) constitutes the default method for time-to-event modeling due to its ability to estimate event probabilities of sparsely occurring events over time. In this work, we show how to improve the training and inference of…

机器学习 · 计算机科学 2023-12-12 Chris Solomou

Bayes linear kinematics and Bayes linear Bayes graphical models provide an extension of Bayes linear methods so that full conditional updates may be combined with Bayes linear belief adjustment. In this paper we investigate the application…

统计方法学 · 统计学 2016-11-16 Kevin J. Wilson , Malcolm Farrow

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

机器学习 · 计算机科学 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

机器学习 · 计算机科学 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Survival analysis is a hotspot in statistical research for modeling time-to-event information with data censorship handling, which has been widely used in many applications such as clinical research, information system and other fields with…

机器学习 · 计算机科学 2018-11-14 Kan Ren , Jiarui Qin , Lei Zheng , Zhengyu Yang , Weinan Zhang , Lin Qiu , Yong Yu

Introduction: Modelling of relative treatment effects is an important aspect to consider when extrapolating the long-term survival outcomes of treatments. Flexible parametric models offer the ability to accurately model the observed data,…

统计方法学 · 统计学 2024-01-02 Philip Cooney , Arthur White

Inspired by applications in sports where the skill of players or teams competing against each other varies over time, we propose a probabilistic model of pairwise-comparison outcomes that can capture a wide range of time dynamics. We…

机器学习 · 统计学 2019-05-20 Lucas Maystre , Victor Kristof , Matthias Grossglauser

In biomedical studies, longitudinal processes are collected till time-to-event, sometimes on nested timescales (example, days within months). Most of the literature in joint modeling of longitudinal and time-to-event data has focused on…

统计方法学 · 统计学 2023-07-19 Abhisek Saha , Ling Ma , Animikh Biswas , Rajeshwari Sundaram

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

We consider planning longitudinal covariate measurements in follow-up studies where covariates are time-varying. We assume that the entire cohort cannot be selected for longitudinal measurements due to financial limitations and study how a…

统计方法学 · 统计学 2024-07-03 Jaakko Reinikainen , Juha Karvanen

Survival analysis is an important area of medical research, yet existing models often struggle to balance simplicity with flexibility. Simple models require minimal adjustments but come with strong assumptions, while more flexible models…

统计方法学 · 统计学 2025-08-22 Peter Knaus , Daniel Winkler , Sebastian F. Schoppmann , Gerd Jomrich

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

机器学习 · 计算机科学 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a novel weighting strategy to account for time-varying…

统计方法学 · 统计学 2023-08-08 Liangyuan Hu , Jiayi Ji , Himanshu Joshi , Erick Scott , Fan Li

Cystic fibrosis is a chronic lung disease which requires frequent patient monitoring to maintain lung function over time and minimize onset of acute respiratory events known as pulmonary exacerbations. From the clinical point of view it is…

To extend cognitive diagnostic models (CDMs) to longitudinal settings, stepwise approaches that integrate a CDM model with a latent transition model and covariates are widely used due to their flexibility. Previous research has shown that…

统计方法学 · 统计学 2026-04-20 Yawen Ma , Anastasia Ushakova , Kate Cain , Gabriel Wallin

Correlated survival data are prevalent in various clinical settings and have been extensively discussed in literature. One of the most common types of correlated survival data is clustered survival data, where the survival times from…

统计方法学 · 统计学 2024-08-02 Chengqian Xian , Camila P. E. de Souza , Wenqing He , Felipe F. Rodrigues , Renfang Tian

Mean arterial blood pressure (MAP) dynamics estimation and its automated regulation could benefit the clinical and emergency resuscitation of critical patients. In order to address the variability and complexity of the MAP response of a…

系统与控制 · 电气工程与系统科学 2020-07-09 Shahin Tasoujian , Saeed Salavati , Matthew Franchek , Karolos Grigoriadis

Longitudinal observational patient data can be used to investigate the causal effects of time-varying treatments on time-to-event outcomes. Several methods have been developed for controlling for the time-dependent confounding that…

统计方法学 · 统计学 2021-10-08 Ruth H. Keogh , Jon Michael Gran , Shaun R. Seaman , Gwyneth Davies , Stijn Vansteelandt

The joint modeling of multiple longitudinal biomarkers together with a time-to-event outcome is a challenging modeling task of continued scientific interest. In particular, the computational complexity of high dimensional (generalized)…

统计方法学 · 统计学 2023-12-12 Alexander Volkmann , Nikolaus Umlauf , Sonja Greven

Joint multivariate longitudinal and time-to-event data are gaining increasing attention in the biomedical sciences where subjects are followed over time to monitor the progress of a disease or medical condition. In the insurance context,…

统计方法学 · 统计学 2019-02-12 Edward W. Frees , Catalina Bolancé , Montserrat Guillen , Emiliano Valdez