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Collective cell migration is a key driver of embryonic development, wound healing, and some types of cancer invasion. Here we provide a physical perspective of the mechanisms underlying collective cell migration. We begin with a catalogue…

生物物理 · 物理学 2019-10-08 Ricard Alert , Xavier Trepat

Animal groups frequently move in a highly organized manner, as represented by flocks of birds and schools of fish. Despite being an everyday occurrence, we do not yet fully understand how this works. What type of social interactions between…

定量方法 · 定量生物学 2021-11-23 Daniel Strömbom , Tasnia Hassan , W. Hunter Greis , Alice Antia

In animal societies as well as in human crowds, many observed collective behaviours result from self-organized processes based on local interactions among individuals. However, models of crowd dynamics are still lacking a systematic…

物理与社会 · 物理学 2009-09-30 Mehdi Moussaid , Dirk Helbing , Simon Garnier , Anders Johansson , Maud Combe , Guy Theraulaz

Consider a flock of birds that fly interacting between them. The interactions are modelled through a hierarchical system in which each bird, at each time step, adjusts its own velocity according to his past velocity and a weighted mean of…

概率论 · 数学 2009-12-24 Federico Dalmao , Ernesto Mordecki

We discuss biologically inspired, inherently non-equilibrium self-propelled particle models, in which the particles interact with their neighbours by choosing at each time step the local average direction of motion. We summarize some of the…

统计力学 · 物理学 2007-05-23 Andras Czirok , Tamas Vicsek

We study a simple swarming model on a two-dimensional lattice where the self-propelled particles exhibit a tendency to align ferromagnetically. Volume exclusion effects are present: particles can only hop to a neighboring node if the node…

生物物理 · 物理学 2013-02-18 Fernando Peruani , Tobias Klauss , Andreas Deutsch , Anja Voss-Boehme

Several models of flocking have been promoted based on simulations with qualitatively naturalistic behavior. In this paper we provide the first direct application of computational modeling methods to infer flocking behavior from…

其他定量生物学 · 定量生物学 2015-05-30 Graciano Dieck Kattas , Xiao-Ke Xu , Michael Small

We study the multi-scale description of large-time collective behavior of agents driven by alignment. The resulting multi-flock dynamics arises naturally with realistic initial configurations consisting of multiple spatial scaling, which in…

偏微分方程分析 · 数学 2020-03-11 Roman Shvydkoy , Eitan Tadmor

Natural groups of animals, such as swarms of social insects, exhibit astonishing degrees of task specialization, useful to address complex tasks and to survive. This is supported by phenotypic plasticity: individuals sharing the same…

机器人学 · 计算机科学 2024-02-08 Fuda van Diggelen , Matteo De Carlo , Nicolas Cambier , Eliseo Ferrante , A. E. Eiben

The self-organised motion of vast numbers of creatures in a single direction is a spectacular example of emergent order. We recreate this phenomenon using actuated non-living components. We report here that millimetre-sized tapered rods,…

软凝聚态物质 · 物理学 2014-09-23 Nitin Kumar , Harsh Soni , Sriram Ramaswamy , A. K. Sood

Thanks to recent technological advances, it is now possible to track with an unprecedented precision and for long periods of time the movement patterns of many living organisms in their habitat. The increasing amount of data available on…

种群与进化 · 定量生物学 2015-05-19 Denis Boyer , Peter D. Walsh

Collective sensing is an emergent phenomenon which enables individuals to estimate a hidden property of the environment through the observation of social interactions. Previous work on collective sensing shows that gregarious individuals…

种群与进化 · 定量生物学 2018-05-24 Stefano Bennati

We analyse collective motion that occurs during rare (large deviation) events in systems of active particles, both numerically and analytically. We discuss the associated dynamical phase transition to collective motion, which occurs when…

Recent studies suggest that non-cooperative behavior such as cannibalism may also be a driving mechanism of collective motion. Motivated by these novel results we introduce a simple model of Brownian particles interacting by pursuit and…

统计力学 · 物理学 2009-11-13 Pawel Romanczuk , Iain D. Couzin , Lutz Schimansky-Geier

Collective control of mobile microrobotic swarms is indispensable for their potential high-impact applications in targeted drug delivery, medical diagnostics, parallel micromanipulation, and environmental sensing and remediation. Lack of…

软凝聚态物质 · 物理学 2018-07-26 Berk Yigit , Yunus Alapan , Metin Sitti

We study a system of interacting self-propelled particles whose walking velocity depends on the stage of the locomotion cycle. The model introduces a phase equation in the optimal velocity model for vehicular traffic. We find that the…

物理与社会 · 物理学 2015-06-23 Takahiro Ezaki , Ryosuke Nishi , Daichi Yanagisawa , Katsuhiro Nishinari

Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search for food, orientation toward light, spreading of off-spring, and the formation of colonies are only possible due to locomotion. Swimming at the…

生物物理 · 物理学 2015-05-26 Jens Elgeti , Roland G. Winkler , Gerhard Gompper

The collective motion of a set of moving entities like people, birds, or other animals, is characterized by groups arising, merging, splitting, and ending. Given the trajectories of these entities, we define and model a structure that…

计算几何 · 计算机科学 2013-03-26 Kevin Buchin , Maike Buchin , Marc van Kreveld , Bettina Speckmann , Frank Staals

The coupling of the internal mechanisms of cell polarization to cell shape deformations and subsequent cell crawling poses many interdisciplinary scientific challenges. Several mathematical approaches have been proposed to model the…

细胞行为 · 定量生物学 2023-11-08 Eduardo Moreno , Robert Großmann , Carsten Beta , Sergio Alonso

We present a model of active particles interacting through a dynamic, heterogeneous environment, leading to emergent collective behaviors without direct agent-to-agent communication. Expanding the resource-dependent framework introduced in…

生物物理 · 物理学 2026-01-22 Gaston Briozzo , Gustavo J. Sibona , Fernando Peruani