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Prostate cancer diagnosis heavily relies on histopathological evaluation, which is subject to variability. While immunohistochemical staining (IHC) assists in distinguishing benign from malignant tissue, it involves increased work, higher…

Hematoxylin and eosin (H&E)-stained slides are central to cancer diagnosis and monitoring, visualizing tissue architecture and cellular morphology. However, H&E lacks the molecular specificity needed to distinguish cell states and…

图像与视频处理 · 电气工程与系统科学 2026-04-14 Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

The detection of nuclei and cells in histology images is of great value in both clinical practice and pathological studies. However, multiple reasons such as morphological variations of nuclei or cells make it a challenging task where…

计算机视觉与模式识别 · 计算机科学 2021-06-28 Yibao Sun , Xingru Huang , Huiyu Zhou , Qianni Zhang

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

定量方法 · 定量生物学 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

We consider the problem of image classification for the purpose of aiding doctors in dermatological diagnosis. Dermatological diagnosis poses two major challenges for standard off-the-shelf techniques: First, the data distribution is…

计算机视觉与模式识别 · 计算机科学 2018-11-08 Viraj Prabhu , Anitha Kannan , Murali Ravuri , Manish Chablani , David Sontag , Xavier Amatriain

Digital pathology has recently been revolutionized by advancements in artificial intelligence, deep learning, and high-performance computing. With its advanced tools, digital pathology can help improve and speed up the diagnostic process,…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Mohamed Elmanna , Ahmed Elsafty , Yomna Ahmed , Muhammad Rushdi , Ahmed Morsy

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Retinal image matching plays a crucial role in monitoring disease progression and treatment response. However, datasets with matched keypoints between temporally separated pairs of images are not available in abundance to train…

计算机视觉与模式识别 · 计算机科学 2023-07-24 Sahar Almahfouz Nasser , Nihar Gupte , Amit Sethi

Immunohistochemical (IHC) images reveal detailed information about structures and functions at the subcellular level. However, unlike natural images, IHC datasets pose challenges for deep learning models due to their inconsistencies in…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Umar Marikkar , Syed Sameed Husain , Muhammad Awais , Sara Atito

Spatial arrangement of cells of various types, such as tumor infiltrating lymphocytes and the advancing edge of a tumor, are important features for detecting and characterizing cancers. However, convolutional neural networks (CNNs) do not…

图像与视频处理 · 电气工程与系统科学 2019-08-15 Shrey Gadiya , Deepak Anand , Amit Sethi

Unlike common cancers, such as those of the prostate and breast, tumor grading in rare cancers is difficult and largely undefined because of small sample sizes, the sheer volume of time needed to undertake on such a task, and the inherent…

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

This study explores the application of supervised and unsupervised autoencoders (AEs) to automate nuclei classification in clear cell renal cell carcinoma (ccRCC) images, a diagnostic task traditionally reliant on subjective visual grading…

图像与视频处理 · 电气工程与系统科学 2025-04-07 Fatemeh Javadian , Zahra Aminparast , Johannes Stegmaier , Abin Jose

Melanoma classification is a serious stage to identify the skin disease. It is considered a challenging process due to the intra-class discrepancy of melanomas, skin lesions low contrast, and the artifacts in the dermoscopy images,…

计算机视觉与模式识别 · 计算机科学 2018-07-27 Yanhui Guo , Amira S. Ashour

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

Histopathology plays a central role in diagnosis of many diseases including solid cancers. Efforts are underway to transform this subjective art form to an objective and quantitative science. Coherent Raman imaging (CRI), a label-free…

医学物理 · 物理学 2018-02-07 Marcus T Cicerone , Charles H. Camp

Skin cancer is by far in top-3 of the world's most common cancer. Among different skin cancer types, melanoma is particularly dangerous because of its ability to metastasize. Early detection is the key to success in skin cancer treatment.…

人工智能 · 计算机科学 2020-09-15 Duyen N. T. Le , Hieu X. Le , Lua T. Ngo , Hoan T. Ngo

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

计算机视觉与模式识别 · 计算机科学 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

Tissue texture is known to exhibit a heterogeneous or non-stationary nature, therefore using a single resolution approach for optimum classification might not suffice. A clinical decision support system that exploits the subband textural…

计算机视觉与模式识别 · 计算机科学 2015-12-29 Omar S. Al-Kadi

Semantic segmentation of functional magnetic resonance imaging (fMRI) makes great sense for pathology diagnosis and decision system of medical robots. The multi-channel fMRI provides more information of the pathological features. But the…

计算机视觉与模式识别 · 计算机科学 2017-07-12 Lei Tai , Haoyang Ye , Qiong Ye , Ming Liu