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Purpose: There is increasing interest in computed tomography (CT) image estimations from magnetic resonance (MR) images. The estimated CT images can be utilised for attenuation correction, patient positioning, and dose planning in…

统计方法学 · 统计学 2019-04-02 Fekadu L. Bayisa , Xijia Liu , Anders Garpebring , Jun Yu

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

计算机视觉与模式识别 · 计算机科学 2016-12-19 Dong Nie , Roger Trullo , Caroline Petitjean , Su Ruan , Dinggang Shen

The generation of synthetic CT (sCT) images from cone-beam CT (CBCT) data using deep learning methodologies represents a significant advancement in radiation oncology. This systematic review, following PRISMA guidelines and using the PICO…

图像与视频处理 · 电气工程与系统科学 2025-01-27 Alzahra Altalib , Scott McGregor , Chunhui Li , Alessandro Perelli

Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone image registration, ultimately reducing patient radiation…

图像与视频处理 · 电气工程与系统科学 2023-06-01 Shaoyan Pan , Elham Abouei , Jacob Wynne , Tonghe Wang , Richard L. J. Qiu , Yuheng Li , Chih-Wei Chang , Junbo Peng , Justin Roper , Pretesh Patel , David S. Yu , Hui Mao , Xiaofeng Yang

Generating synthetic CT (sCT) from MRI or CBCT plays a crucial role in enabling MRI-only and CBCT-based adaptive radiotherapy, improving treatment precision while reducing patient radiation exposure. To address this task, we adopt a fully…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Arnela Hadzic , Simon Johannes Joham , Martin Urschler

Model-based treatment planning for transcranial ultrasound therapy typically involves mapping the acoustic properties of the skull from an x-ray computed tomography (CT) image of the head. Here, three methods for generating pseudo-CT images…

Currently, MRI-only radiotherapy (RT) eliminates some of the concerns about using CT images in RT chains such as the registration of MR images to a separate CT, extra dose delivery, and the additional cost of repeated imaging. However, one…

医学物理 · 物理学 2021-03-03 Faeze Gholamiankhah , Samaneh Mostafapour , Hossein Arabi

Quantifying normative pediatric cranial development and suture ossification is crucial for diagnosing and treating growth-related cephalic disorders. Computed tomography (CT) is widely used to evaluate cranial and sutural deformities;…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Krithika Iyer , Austin Tapp , Athelia Paulli , Gabrielle Dickerson , Syed Muhammad Anwar , Natasha Lepore , Marius George Linguraru

To enable magnetic resonance (MR)-only radiotherapy and facilitate modelling of radiation attenuation in humans, synthetic-CT (sCT) images need to be generated. Considering the application of MR-guided radiotherapy and online adaptive…

We develop here a semiparametric Gaussian mixture model (SGMM) for unsupervised learning with valuable spatial information taken into consideration. Specifically, we assume for each instance a random location. Then, conditional on this…

统计方法学 · 统计学 2025-10-21 Baichen Yu , Jin Liu , Hansheng Wang

Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image…

图像与视频处理 · 电气工程与系统科学 2023-08-16 Denis Prokopenko , Joël Valentin Stadelmann , Heinrich Schulz , Steffen Renisch , Dmitry V. Dylov

Automatically generating one medical imaging modality from another is known as medical image translation, and has numerous interesting applications. This paper presents an interpretable generative modelling approach to medical image…

图像与视频处理 · 电气工程与系统科学 2020-05-08 Mikael Brudfors , John Ashburner , Parashkev Nachev , Yael Balbastre

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

图像与视频处理 · 电气工程与系统科学 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

The ability to synthesise Computed Tomography images - commonly known as pseudo CT, or pCT - from MRI input data is commonly assessed using an intensity-wise similarity, such as an L2-norm between the ground truth CT and the pCT. However,…

Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…

医学物理 · 物理学 2025-07-14 Hengyu Gao , Shaodong Ding , Ziyang Liu , Jiefu Zhang , Bolun Li , Zhiwu An , Li Wang , Jing Jing , Tao Liu , Yubo Fan , Zhongtao Hu

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

图像与视频处理 · 电气工程与系统科学 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Computed tomography (CT) has been a powerful diagnostic tool since its emergence in the 1970s. Using CT data, three-dimensional (3D) structures of human internal organs and tissues, such as blood vessels, can be reconstructed using…

应用统计 · 统计学 2024-04-01 Qianhan Zeng , Jing Zhou , Ying Ji , Hansheng Wang

The aim of this paper is to develop a class of spatial transformation models (STM) to spatially model the varying association between imaging measures in a three-dimensional (3D) volume (or 2D surface) and a set of covariates. Our STMs…

应用统计 · 统计学 2016-07-27 Michelle F. Miranda , Hongtu Zhu , Joseph G. Ibrahim

Score-based generative models (SGMs) have recently shown promising results for image reconstruction on simulated positron emission tomography (PET) datasets. In this work we have developed and implemented practical methodology for 3D image…

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