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Deep neural networks (DNNs) achieve remarkable predictive performance but remain difficult to interpret, largely due to overparameterization that obscures the minimal structure required for interpretation. Here we introduce DeepIn, a…

统计方法学 · 统计学 2026-03-26 Zhiyao Tan , Liu Li , Huazhen Lin

Inferring parameters of macro-kinetic growth models, typically represented by Ordinary Differential Equations (ODE), from the experimental data is a crucial step in bioprocess engineering. Conventionally, estimates of the parameters are…

机器学习 · 计算机科学 2023-12-07 Maxim Borisyak , Stefan Born , Peter Neubauer , Mariano Nicolas Cruz-Bournazou

The mining and utilization of features directly affect the classification performance of models used in the classification and recognition of hyperspectral remote sensing images. Traditional models usually conduct feature mining from a…

计算机视觉与模式识别 · 计算机科学 2021-06-29 Yunsong Zhao , Yin Li , Zhihan Chen , Tianchong Qiu , Guojin Liu

With the success of pretraining techniques in representation learning, a number of continual learning methods based on pretrained models have been proposed. Some of these methods design continual learning mechanisms on the pre-trained…

计算机视觉与模式识别 · 计算机科学 2023-03-30 Paul Janson , Wenxuan Zhang , Rahaf Aljundi , Mohamed Elhoseiny

While deep neural networks take loose inspiration from neuroscience, it is an open question how seriously to take the analogies between artificial deep networks and biological neuronal systems. Interestingly, recent work has shown that deep…

神经元与认知 · 定量生物学 2018-05-31 William Lotter , Gabriel Kreiman , David Cox

Deep neural networks have recently achieved state of the art performance thanks to new training algorithms for rapid parameter estimation and new regularization methods to reduce overfitting. However, in practice the network architecture…

机器学习 · 计算机科学 2016-03-04 Minyoung Kim , Luca Rigazio

Thanks to their universal approximation properties and new efficient training strategies, Deep Neural Networks are becoming a valuable tool for the approximation of mathematical operators. In the present work, we introduce Mesh-Informed…

数值分析 · 数学 2023-05-08 Nicola Rares Franco , Andrea Manzoni , Paolo Zunino

While data are the primary fuel for machine learning models, they often suffer from missing values, especially when collected in real-world scenarios. However, many off-the-shelf machine learning models, including artificial neural network…

Long non-coding RNA, microRNA, and messenger RNA enable key regulations of various biological processes through a variety of diverse interaction mechanisms. Identifying the interactions and cross-talk between these heterogeneous RNA classes…

分子网络 · 定量生物学 2020-12-10 Nhat Tran , Jean Gao

Training deep recurrent neural network (RNN) architectures is complicated due to the increased network complexity. This disrupts the learning of higher order abstracts using deep RNN. In case of feed-forward networks training deep…

计算与语言 · 计算机科学 2018-08-07 Murali Karthick Baskar , Martin Karafiat , Lukas Burget , Karel Vesely , Frantisek Grezl , Jan Honza Cernocky

What is the best way to exploit extra data -- be it unlabeled data from the same task, or labeled data from a related task -- to learn a given task? This paper formalizes the question using the theory of reference priors. Reference priors…

机器学习 · 统计学 2022-06-17 Yansong Gao , Rahul Ramesh , Pratik Chaudhari

The characterization of drug-protein interactions is crucial in the high-throughput screening for drug discovery. The deep learning-based approaches have attracted attention because they can predict drug-protein interactions without…

机器学习 · 计算机科学 2020-12-22 QHwan Kim , Joon-Hyuk Ko , Sunghoon Kim , Nojun Park , Wonho Jhe

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

图像与视频处理 · 电气工程与系统科学 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain…

图像与视频处理 · 电气工程与系统科学 2023-06-23 M. Tanveer , M. A. Ganaie , Iman Beheshti , Tripti Goel , Nehal Ahmad , Kuan-Ting Lai , Kaizhu Huang , Yu-Dong Zhang , Javier Del Ser , Chin-Teng Lin

Registration is the process that computes the transformation that aligns sets of data. Commonly, a registration process can be divided into four main steps: target selection, feature extraction, feature matching, and transform computation…

计算机视觉与模式识别 · 计算机科学 2020-10-29 Victor Villena-Martinez , Sergiu Oprea , Marcelo Saval-Calvo , Jorge Azorin-Lopez , Andres Fuster-Guillo , Robert B. Fisher

Motivation: Spliced alignment refers to the alignment of messenger RNA (mRNA) or protein sequences to eukaryotic genomes. It plays a critical role in gene annotation and the study of gene functions. Accurate spliced alignment demands…

基因组学 · 定量生物学 2025-09-23 Siying Yang , Neng Huang , Heng Li

Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in thus needed to understand the cell's working mechanism, and…

定量方法 · 定量生物学 2011-02-21 Fantine Mordelet , Jean-Philippe Vert

Research on remote sensing image classification significantly impacts essential human routine tasks such as urban planning and agriculture. Nowadays, the rapid advance in technology and the availability of many high-quality remote sensing…

计算机视觉与模式识别 · 计算机科学 2022-12-21 Daniel F. S. Santos , Rafael G. Pires , Leandro A. Passos , João P. Papa

Background: When using deep learning models, there are many possible vulnerabilities and some of the most worrying are the adversarial inputs, which can cause wrong decisions with minor perturbations. Therefore, it becomes necessary to…

软件工程 · 计算机科学 2024-01-12 Francisco Durán López , Silverio Martínez-Fernández , Michael Felderer , Xavier Franch

Deep neural networks (DNN) have been deployed in many software systems to assist in various classification tasks. In company with the fantastic effectiveness in classification, DNNs could also exhibit incorrect behaviors and result in…

软件工程 · 计算机科学 2020-06-16 Yang Feng , Qingkai Shi , Xinyu Gao , Jun Wan , Chunrong Fang , Zhenyu Chen