相关论文: New algorithmic challenges of adaptive immune repe…

The recent success of machine learning methods applied to time series collected from Intensive Care Units (ICU) exposes the lack of standardized machine learning benchmarks for developing and comparing such methods. While raw datasets, such…

By generating new yet effective data, data augmentation has become a promising method to mitigate the data sparsity problem in sequential recommendation. Existing works focus on augmenting the original data but rarely explore the issue of…

Realistic recommender systems are often required to adapt to ever-changing data and tasks or to explore different models systematically. To address the need, we present AutoRec, an open-source automated machine learning (AutoML) platform…

We describe the Microbial Community Reconstruction ({\bf MCR}) Problem, which is fundamental for microbiome analysis. In this problem, the goal is to reconstruct the identity and frequency of species comprising a microbial community, using…

Epitopes are short antigenic peptide sequences which are recognized by antibodies or immune cell receptors. These are central to the development of immunotherapies, vaccines, and diagnostics. However, the rational design of synthetic…

Characterizing users' interests accurately plays a significant role in an effective recommender system. The sequential recommender system can learn powerful hidden representations of users from successive user-item interactions and dynamic…

The adaptive immune response relies on T cells that combine phenotypic specialization with diversity of T cell receptors (TCRs) to recognize a wide range of pathogens. TCRs are acquired and selected during T cell maturation in the thymus.…

This paper presents advancements in automated early-stage prediction of the success of reprogramming human induced pluripotent stem cells (iPSCs) as a potential source for regenerative cell therapies.The minuscule success rate of…

Sequential recommendation aims to predict a user's next action in large-scale recommender systems. While traditional methods often suffer from insufficient information interaction, recent generative recommendation models partially address…

Temporal Information Retrieval (TIR) is a critical yet unresolved task for modern search systems, retrieving documents that not only satisfy a query's information need but also adhere to its temporal constraints. This task is shaped by two…

Generative models, particularly diffusion model, have emerged as powerful tools for sequential recommendation. However, accurately modeling user preferences remains challenging due to the noise perturbations inherent in the forward and…

Designing protein sequences with desired biological function is crucial in biology and chemistry. Recent machine learning methods use a surrogate sequence-function model to replace the expensive wet-lab validation. How can we efficiently…

Traditional recommendation systems suffer from inconsistency in multi-stage optimization objectives. Generative Recommendation (GR) mitigates them through an end-to-end framework; however, existing methods still rely on matching mechanisms…

Transformer-based recommender systems, such as BERT4Rec or SASRec, achieve state-of-the-art results in sequential recommendation. However, it is challenging to use these models in production environments with catalogues of millions of…

Sequential recommender systems have demonstrated strong capabilities in modeling users' dynamic preferences and capturing item transition patterns. However, real-world user behaviors are often noisy due to factors such as human errors,…

Magnetic Resonance Imaging (MRI) is a powerful, non-invasive diagnostic tool; however, its clinical applicability is constrained by prolonged acquisition times. Whilst present deep learning-based approaches have demonstrated potential in…

Accurate multi-step port-of-call sequence prediction is vital for tactical resource orchestration and logistical efficiency. However, existing methods struggle with unreliable voyage schedules and the inability of AIS data to provide…

Deep neural networks have emerged as a powerful technique for learning representations from user-item interaction data in collaborative filtering (CF) for recommender systems. However, many existing methods heavily rely on unique user and…

Learning-based methods have demonstrated remarkable performance in solving inverse problems, particularly in image reconstruction tasks. Despite their success, these approaches often lack theoretical guarantees, which are crucial in…

Antibodies comprise the most versatile class of binding molecules, with numerous applications in biomedicine. Computational design of antibodies involves generating novel and diverse sequences, while maintaining structural consistency.…