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The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

神经元与认知 · 定量生物学 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Studying neural connectivity is considered one of the most promising and challenging areas of modern neuroscience. The underpinnings of cognition are hidden in the way neurons interact with each other. However, our experimental methods of…

机器学习 · 统计学 2018-06-22 George Panagopoulos

Various research initiatives try to utilize the operational principles of organisms and brains to develop alternative, biologically inspired computing paradigms and artificial cognitive systems. This paper reviews key features of the…

适应与自组织系统 · 物理学 2012-01-25 Andreas Schierwagen

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

The human brain receives complex inputs when performing cognitive tasks, which range from external inputs via the senses to internal inputs from other brain regions. However, the explicit inputs to the brain during a cognitive task remain…

神经元与认知 · 定量生物学 2024-04-26 Zhichao Liang , Yinuo Zhang , Jushen Wu , Quanying Liu

Laboratory-grown, engineered living neuronal networks in vitro have emerged in the last years as an experimental technique to understand the collective behavior of neuronal assemblies in relation to their underlying connectivity. An…

神经元与认知 · 定量生物学 2025-01-09 Akke Mats Houben , Jordi Garcia-Ojalvo , Jordi Soriano

Interdisciplinary scientific research is increasingly important in knowledge production, funding policies, and academic discussions on scholarly communication. While many studies focus on interdisciplinary corpora defined a priori --…

数字图书馆 · 计算机科学 2025-10-29 Malena Mendez Isla , Agustin Mauro , Diego Kozlowski

Brain network provides important insights for the diagnosis of many brain disorders, and how to effectively model the brain structure has become one of the core issues in the domain of brain imaging analysis. Recently, various computational…

神经元与认知 · 定量生物学 2022-12-02 Zhengwang Xia , Tao Zhou , Saqib Mamoon , Amani Alfakih , Jianfeng Lu

The advent of comprehensive synaptic wiring diagrams of large neural circuits has created the field of connectomics and given rise to a number of open research questions. One such question is whether it is possible to reconstruct the…

神经元与认知 · 定量生物学 2023-02-20 Sebastian Goldt , Florent Krzakala , Lenka Zdeborová , Nicolas Brunel

This paper presents a comprehensive and quality collection of functional human brain network data for potential research in the intersection of neuroscience, machine learning, and graph analytics. Anatomical and functional MRI images have…

Function and dysfunctions of neural systems are tied to the temporal evolution of neural states. The current limitations in showing their causal role stem largely from the absence of tools capable of probing the brain's internal state in…

This paper studies causal discovery in irregularly sampled time series-a key challenge in risk-sensitive domains like finance, healthcare, and climate science, where missing data and inconsistent sampling frequencies distort causal…

机器学习 · 计算机科学 2026-05-12 Weihong Li , Baohong Li , Anpeng Wu , Zhihan Li , Ming Ma , Keting Yin , Kun Kuang

Reconstructing multiple molecularly defined neurons from individual brains and across multiple brain regions can reveal organizational principles of the nervous system. However, high resolution imaging of the whole brain is a technically…

计算机视觉与模式识别 · 计算机科学 2019-03-19 James Gornet , Kannan Umadevi Venkataraju , Arun Narasimhan , Nicholas Turner , Kisuk Lee , H. Sebastian Seung , Pavel Osten , Uygar Sümbül

The analysis of brain connectivity aims to understand the emergence of functional networks into the brain. This information can be used in the process of electroencephalographic (EEG) signal analysis and classification for a braincomputer…

神经元与认知 · 定量生物学 2020-07-28 J. A. Gaxiola-Tirado

Artificial Neural Networks (ANNs) inspired by biology are beginning to be widely used to model behavioral and neural data, an approach we call neuroconnectionism. ANNs have been lauded as the current best models of information processing in…

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

应用统计 · 统计学 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Data produced by resting-state functional Magnetic Resonance Imaging are widely used to infer brain functional connectivity networks. Such networks correlate neural signals to connect brain regions, which consist in groups of dependent…

统计方法学 · 统计学 2023-12-05 Hanâ Lbath , Alexander Petersen , Sophie Achard

Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matching…

统计方法学 · 统计学 2025-03-21 Martin Cole , Yang Xiang , Will Consagra , Anuj Srivastava , Xing Qiu , Zhengwu Zhang

This article presents a review of computational methods for connectivity inference from neural activity data derived from multi-electrode recordings or fluorescence imaging. We first identify biophysical and technical challenges in…

神经元与认知 · 定量生物学 2017-12-18 Ildefons Magrans de Abril , Junichiro Yoshimoto , Kenji Doya