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Bacterial heterogeneity is pivotal for adaptation to diverse environments, posing significant challenges in microbial diagnostics and therapeutic interventions. Recent advancements in high-resolution optical microscopy have revolutionized…

Optical coherence tomography (OCT) is a volumetric imaging modality that empowers clinicians and scientists to noninvasively visualize the cross-sections of biological samples. As the latest generation of its kind, Fourier-domain OCT…

图像与视频处理 · 电气工程与系统科学 2020-05-20 Yuye Ling , Mengyuan Wang , Yu Gan , Xinwen Yao , Leopold Schmetterer , Chuanqing Zhou , Yikai Su

At the present time Optical Coherence Tomography (OCT) is among the most commonly used non-invasive imaging methods for the acquisition of large volumetric scans of human retinal tissues and vasculature. To resolve decisive information from…

计算机视觉与模式识别 · 计算机科学 2021-11-02 D. Sitenko , B. Boll , C. Schnörr

The field of biomedical imaging has undergone a rapid growth in recent years, mostly due to the implementation of ad-hoc designed experimental setups, theoretical support methods and numerical reconstructions. Especially for biological…

生物物理 · 物理学 2017-06-30 Daniele Ancora

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

We report a computational 3D microscopy technique, termed Fourier ptychographic diffraction tomography (FPDT), that iteratively stitches together numerous variably illuminated, low-resolution images acquired with a low-numerical aperture…

光学 · 物理学 2020-02-19 Chao Zuo , Jiasong Sun , Jiaji Li , Anand Asundi , Qian Chen

Optical diffraction tomography (ODT) reconstructs a samples volumetric refractive index (RI) to create high-contrast, quantitative 3D visualizations of biological samples. However, standard implementations of ODT use interferometric…

图像与视频处理 · 电气工程与系统科学 2024-12-13 Shwetadwip Chowdhury , Michael Chen , Regina Eckert , David Ren , Fan Wu , Nicole Repina , Laura Waller

Medical image segmentation is crucial for many healthcare tasks, including disease diagnosis and treatment planning. One key area is the segmentation of skin lesions, which is vital for diagnosing skin cancer and monitoring patients. In…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Salah Eddine Bekhouche , Gaby Maroun , Fadi Dornaika , Abdenour Hadid

Optical diffraction tomography (ODT) provides three-dimensional refractive index (RI) tomograms of a transparent microscopic object. However, because of the finite numerical aperture of objective lenses, ODT has the limited access to…

光学 · 物理学 2017-11-22 Moosung Lee , Seungwoo Shin , YongKeun Park

There is an increasing need for label free methods that could reveal intracellular structures and dynamics. In this context, we develop a new optical tomography method working in transmission - Full-field optical transmission tomography…

Computer-aided diagnostics has benefited from the development of deep learning-based computer vision techniques in these years. Traditional supervised deep learning methods assume that the test sample is drawn from the identical…

计算机视觉与模式识别 · 计算机科学 2024-07-04 Zesheng Hong , Yubiao Yue , Yubin Chen , Lele Cong , Huanjie Lin , Yuanmei Luo , Mini Han Wang , Weidong Wang , Jialong Xu , Xiaoqi Yang , Hechang Chen , Zhenzhang Li , Sihong Xie

Optical Coherence Tomography (OCT) has become one of the most used imaging modality in ophthalmology. It provides high-resolution, non-invasive visualization of retinal microarchitecture. The automated analysis of OCT images through…

计算机视觉与模式识别 · 计算机科学 2026-05-05 Hedi Tabia , Désiré Sidibé , Nawres Khlifa , Ahmed Tabia , Ines Rahmany , Noura Aboudi , Zainab Haddad , Hajer Khachnaoui , Hsouna Zgolli

Herein is presented an optical diffraction tomography (ODT) technique for measuring 3-D refractive index (RI) maps of optical plastic lenses. A Mach-Zehnder interferometer was used to measure multiple complex optical fields of a plastic…

光学 · 物理学 2016-04-20 Kyoohyun Kim , Jonghee Yoon , YongKeun Park

This paper reports on advances in optical coherence tomography (OCT) for application in dermatology. Full-field OCT is a particular approach of OCT based on white-light interference microscopy. FF-OCT produces en face tomographic images by…

医学物理 · 物理学 2018-04-06 Olivier Levecq , Arthur Davis , Hicham Azimani , David Siret , Jean-Luc Perrot , Arnaud Dubois

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

图像与视频处理 · 电气工程与系统科学 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

Recent advances in optical technology have significantly enhanced the resolution of imaging of living cells, achieving nanometer-scale precision. However, the crowded three-dimensional environment within cells presents a challenge for…

光学 · 物理学 2024-11-20 Vahid Nasirimarekani , Zuzana Ditte , Eberhard Bodenschatz

Many biological and soft matter processes occur at high speeds in complex 3D environments, and developing imaging techniques capable of elucidating their dynamics is an outstanding experimental challenge. Here, we introduce Fourier…

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

医学物理 · 物理学 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

The interest in using optical transition radiation (OTR) in high energy (multiGeV) beam diagnostics has motivated theoretical and experimental investigations on the limitations brought by diffraction on the attainable resolution. This paper…

加速器物理 · 物理学 2007-05-23 X. Artru , R. Chehab , K. Honkavaara , A. Variola