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A new shrinkage-based construction is developed for a compressible vector $\boldsymbol{x}\in\mathbb{R}^n$, for cases in which the components of $\xv$ are naturally associated with a tree structure. Important examples are when $\xv$…

机器学习 · 统计学 2014-01-14 Xin Yuan , Vinayak Rao , Shaobo Han , Lawrence Carin

Gaussian Graphical Models (GGMs) or Gauss Markov random fields are widely used in many applications, and the trade-off between the modeling capacity and the efficiency of learning and inference has been an important research problem. In…

机器学习 · 计算机科学 2013-11-12 Ying Liu , Alan S. Willsky

Stochastic models with global parameters and latent variables are common, and for which variational inference (VI) is popular. However, existing methods are often either slow or inaccurate in high dimensions. We suggest a fast and accurate…

Non-linear hierarchical models are commonly used in many disciplines. However, inference in the presence of non-nested effects and on large datasets is challenging and computationally burdensome. This paper provides two contributions to…

统计方法学 · 统计学 2021-10-22 Max Goplerud

Biological spiking neurons with intrinsic dynamics underlie the powerful representation and learning capabilities of the brain for processing multimodal information in complex environments. Despite recent tremendous progress in spiking…

神经与进化计算 · 计算机科学 2021-07-15 Mingkun Xu , Yujie Wu , Lei Deng , Faqiang Liu , Guoqi Li , Jing Pei

Scale-mixture shrinkage priors have recently been shown to possess robust empirical performance and excellent theoretical properties such as model selection consistency and (near) minimax posterior contraction rates. In this paper, the…

统计方法学 · 统计学 2022-12-27 Ahmed Alhamzawi , Gorgees Shaheed Mohammad

In some cases, computational benefit can be gained by exploring the hyper parameter space using a deterministic set of grid points instead of a Markov chain. We view this as a numerical integration problem and make three unique…

统计计算 · 统计学 2016-09-30 Chaitanya Joshi , Paul T. Brown , Stephen Joe

We extend the wavelet tests for fixed effects FANOVA models with iid errors, proposed in Abramovich et al, 2004 to FANOVA models with dependent errors and provide an iterative Cochrane-Orcutt type procedure to estimate the parameters and…

统计方法学 · 统计学 2015-11-03 Airton Kist , Aluisio Pinheiro

While working within the spatial domain can pose problems associated with ill-conditioned scores caused by power-law decay, recent advances in diffusion-based generative models have shown that transitioning to the wavelet domain offers a…

Understanding how brain structure and function interact is key to explaining intelligence yet modeling them jointly is challenging as the structural and functional connectome capture complementary aspects of organization. We introduced…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Badhan Mazumder , Sir-Lord Wiafe , Aline Kotoski , Vince D. Calhoun , Dong Hye Ye

Score-based models have recently been introduced as a richer framework to model distributions in high dimensions and are generally more suitable for generative tasks. In score-based models, a generative task is formulated using a parametric…

机器学习 · 计算机科学 2023-02-07 Harsh Mishra , Jurijs Nazarovs , Manmohan Dogra , Sathya N. Ravi

In silico methods evaluating the mutation effects of missense mutations are providing an important approach for understanding mutations in personal genomes and identifying disease-relevant biomarkers. However, existing methods, including…

定量方法 · 定量生物学 2024-06-14 Boshen Wang , Bowei Ye , Lin Xu , Jie Liang

There is an increasing demand for computing the relevant structures, equilibria and long-timescale kinetics of biomolecular processes, such as protein-drug binding, from high-throughput molecular dynamics simulations. Current methods employ…

机器学习 · 统计学 2018-02-07 Andreas Mardt , Luca Pasquali , Hao Wu , Frank Noé

The statistical analysis of group studies in neuroscience is particularly challenging due to the complex spatio-temporal nature of the data, its multiple levels and the inter-individual variability in brain responses. In this respect,…

统计方法学 · 统计学 2025-05-15 Nicolò Margaritella , Vanda Inácio , Ruth King

We introduce TANGO -- a dynamical systems inspired framework for graph representation learning that governs node feature evolution through a learned energy landscape and its associated descent dynamics. At the core of our approach is a…

机器学习 · 计算机科学 2025-08-08 Moshe Eliasof , Eldad Haber , Carola-Bibiane Schönlieb

Multivariate machine learning methods are increasingly used to analyze neuroimaging data, often replacing more traditional "mass univariate" techniques that fit data one voxel at a time. In the functional magnetic resonance imaging (fMRI)…

Nonnegative matrix factorization (NMF) is a linear dimensionality reduction technique for analyzing nonnegative data. A key aspect of NMF is the choice of the objective function that depends on the noise model (or statistics of the noise)…

机器学习 · 计算机科学 2021-02-10 Nicolas Gillis , Le Thi Khanh Hien , Valentin Leplat , Vincent Y. F. Tan

Markov networks (MNs) are a powerful way to compactly represent a joint probability distribution, but most MN structure learning methods are very slow, due to the high cost of evaluating candidates structures. Dependency networks (DNs)…

机器学习 · 计算机科学 2012-10-19 Daniel Lowd

Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

统计方法学 · 统计学 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

Most of the existing wavelet image processing techniques are carried out in the form of single-scale reconstruction and multiple iterations. However, processing high-quality fMRI data presents problems such as mixed noise and excessive…

图像与视频处理 · 电气工程与系统科学 2024-06-26 Lingxi Xiao , Jinxin Hu , Yutian Yang , Yinqiu Feng , Zichao Li , Zexi Chen