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We use nucleosome maps obtained by high-throughput sequencing to study sequence specificity of intrinsic histone-DNA interactions. In contrast with previous approaches, we employ an analogy between a classical one-dimensional fluid of…

基因组学 · 定量生物学 2015-05-18 George Locke , Denis Tolkunov , Zarmik Moqtaderi , Kevin Struhl , Alexandre V. Morozov

The advent of experimental science facilities-instruments and observatories, such as the Large Hadron Collider, the Laser Interferometer Gravitational Wave Observatory, and the upcoming Large Synoptic Survey Telescope-has brought about…

分布式、并行与集群计算 · 计算机科学 2019-02-12 E. A. Huerta , Roland Haas , Shantenu Jha , Mark Neubauer , Daniel S. Katz

We outline a quantum-enabled blockchain architecture based on a consortium of quantum servers. The network is hybridised, utilising digital systems for sharing and processing classical information combined with a fibre--optic infrastructure…

量子物理 · 物理学 2019-07-30 Adam J Bennet , Shakib Daryanoosh

Blockchain is a decentralized, distributed ledger technology that ensures transparency, security, and immutability through cryptographic techniques. However, advancements in quantum computing threaten the security of classical cryptographic…

密码学与安全 · 计算机科学 2026-01-14 Nicholas J. C. Papadopoulos

With the advent of quantum computing, cryptocurrencies that rely on blockchain technology face mounting cryptographic vulnerabilities. This paper presents a comprehensive literature review evaluating how quantum algorithms, specifically…

密码学与安全 · 计算机科学 2025-09-09 Adi Mutha , Jitendra Sandu

Based on the cryptocurrency market dynamics, this study presents a general methodology for analyzing evolving correlation structures in complex systems using the $q$-dependent detrended cross-correlation coefficient \rho(q,s). By extending…

统计金融 · 定量金融 2025-10-29 Marcin Wątorek , Marija Bezbradica , Martin Crane , Jarosław Kwapień , Stanisław Drożdż

Cryptocurrency mining processes always lead to a high energy consumption at considerably high production cost, which is nearly one-third of cryptocurrency (e.g. Bitcoin) price itself. As the core of mining process is based on SHA-256…

新兴技术 · 计算机科学 2024-01-23 Ahmet Orun , Fatih Kurugollu

The continually increasing volume of DNA sequence data has resulted in a growing demand for fast implementations of core algorithms. Computation of pairwise alignments between candidate haplotypes and sequencing reads using Pair-HMMs is a…

分布式、并行与集群计算 · 计算机科学 2026-01-27 Bertil Schmidt , Felix Kallenborn , Alexander Wichmann , Alejandro Chacon , Christian Hundt

High throughput sequencing (HTS)-based technology enables identifying and quantifying non-culturable microbial organisms in all environments. Microbial sequences have enhanced our understanding of the human microbiome, the soil and plant…

应用统计 · 统计学 2021-03-09 Pratheepa Jeganathan , Susan P. Holmes

In an age where sustainability is of paramount importance, the significance of both high-performance computing and intelligent algorithms cannot be understated. Yet, these domains often demand hefty computational power, translating to…

分布式、并行与集群计算 · 计算机科学 2025-12-01 Murat Yaslioglu

Most people around the globe are dying due to heart disease. The main reason behind the rapid increase in the death rate due to heart disease is that there is no infrastructure developed for the healthcare department that can provide a…

机器学习 · 计算机科学 2023-06-06 Muhammad Shoaib Farooq , Kiran Amjad

Cryptocurrency is a well-developed blockchain technology application that is currently a heated topic throughout the world. The public availability of transaction histories offers an opportunity to analyze and compare different…

统计金融 · 定量金融 2018-08-28 Jiaqi Liang , Linjing Li , Daniel Zeng

Over the recent years, the field of whole metagenome shotgun sequencing has witnessed significant growth due to the high-throughput sequencing technologies that allow sequencing genomic samples cheaper, faster, and with better coverage than…

基因组学 · 定量生物学 2014-04-04 Sohan Seth , Niko Välimäki , Samuel Kaski , Antti Honkela

Reducing the cost of sequencing genomes provided by next-generation sequencing technologies has greatly increased the number of genomic projects. As a result, there is a growing need for better assembly and assembly validation methods. One…

基因组学 · 定量生物学 2022-10-17 Przemysław Stawczyk , Robert Nowak

High-utility sequential pattern mining (HUSPM) has recently emerged as a focus of intense research interest. The main task of HUSPM is to find all subsequences, within a quantitative sequential database, that have high utility with respect…

数据库 · 计算机科学 2020-11-30 Chunkai Zhang , Zilin Du , Wensheng Gan , Philip S. Yu

The sharing economy is centralizing services, leading to misuses of the Internet. We can list growing damages of data hacks, global outages and even the use of data to manipulate their owners. Unfortunately, there is no decentralized web…

分布式、并行与集群计算 · 计算机科学 2022-03-24 Deepal Tennakoon , Yiding Hua , Vincent Gramoli

The CMS experiment at the CERN LHC will be upgraded to accommodate the 5-fold increase in the instantaneous luminosity expected at the High-Luminosity LHC (HL-LHC). Concomitant with this increase will be an increase in the number of…

仪器与探测器 · 物理学 2021-04-28 B. Acar , G. Adamov , C. Adloff , S. Afanasiev , N. Akchurin , B. Akgün , M. Alhusseini , J. Alison , G. Altopp , M. Alyari , S. An , S. Anagul , I. Andreev , M. Andrews , P. Aspell , I. A. Atakisi , O. Bach , A. Baden , G. Bakas , A. Bakshi , P. Bargassa , D. Barney , E. Becheva , P. Behera , A. Belloni , T. Bergauer , M. Besancon , S. Bhattacharya , S. Bhattacharya , D. Bhowmik , P. Bloch , A. Bodek , M. Bonanomi , A. Bonnemaison , S. Bonomally , J. Borg , F. Bouyjou , D. Braga , J. Brashear , E. Brondolin , P. Bryant , J. Bueghly , B. Bilki , B. Burkle , A. Butler-Nalin , S. Callier , D. Calvet , X. Cao , B. Caraway , S. Caregari , L. Ceard , Y. C. Cekmecelioglu , G. Cerminara , N. Charitonidis , R. Chatterjee , Y. M. Chen , Z. Chen , K. y. Cheng , S. Chernichenko , H. Cheung , C. H. Chien , S. Choudhury , D. Čoko , G. Collura , F. Couderc , I. Dumanoglu , D. Dannheim , P. Dauncey , A. David , G. Davies , E. Day , P. DeBarbaro , F. De Guio , C. de La Taille , M. De Silva , P. Debbins , E. Delagnes , J. M. Deltoro , G. Derylo , P. G. Dias de Almeida , D. Diaz , P. Dinaucourt , J. Dittmann , M. Dragicevic , S. Dugad , V. Dutta , S. Dutta , J. Eckdahl , T. K. Edberg , M. El Berni , S. C. Eno , Yu. Ershov , P. Everaerts , S. Extier , F. Fahim , C. Fallon , B. A. Fontana Santos Alves , E. Frahm , G. Franzoni , J. Freeman , T. French , E. Gurpinar Guler , Y. Guler , M. Gagnan , P. Gandhi , S. Ganjour , A. Garcia-Bellido , Z. Gecse , Y. Geerebaert , H. Gerwig , O. Gevin , W. Gilbert , A. Gilbert , K. Gill , C. Gingu , S. Gninenko , A. Golunov , I. Golutvin , T. Gonzalez , N. Gorbounov , L. Gouskos , Y. Gu , F. Guilloux , E. Gülmez , M. Hammer , A. Harilal , K. Hatakeyama , A. Heering , V. Hegde , U. Heintz , V. Hinger , N. Hinton , J. Hirschauer , J. Hoff , W. S. Hou , C. Isik , J. Incandela , S. Jain , H. R. Jheng , U. Joshi , O. Kara , V. Kachanov , A. Kalinin , R. Kameshwar , A. Kaminskiy , A. Karneyeu , O. Kaya , M. Kaya , A. Khukhunaishvili , S. Kim , K. Koetz , T. Kolberg , A. Kristić , M. Krohn , K. Krüger , N. Kulagin , S. Kulis , S. Kunori , C. M. Kuo , V. Kuryatkov , S. Kyre , O. K. Köseyan , Y. Lai , K. Lamichhane , G. Landsberg , J. Langford , M. Y. Lee , A. Levin , A. Li , B. Li , J. -H. Li , H. Liao , D. Lincoln , L. Linssen , R. Lipton , Y. Liu , A. Lobanov , R. S. Lu , I. Lysova , A. M. Magnan , F. Magniette , A. A. Maier , A. Malakhov , I. Mandjavize , M. Mannelli , J. Mans , A. Marchioro , A. Martelli , P. Masterson , B. Meng , T. Mengke , A. Mestvirishvili , I. Mirza , S. Moccia , I. Morrissey , T. Mudholkar , J. Musić , I. Musienko , S. Nabili , A. Nagar , A. Nikitenko , D. Noonan , M. Noy , K. Nurdan , C. Ochando , B. Odegard , N. Odell , Y. Onel , W. Ortez , J. Ozegović , L. Pacheco Rodriguez , E. Paganis , D. Pagenkopf , V. Palladino , S. Pandey , F. Pantaleo , C. Papageorgakis , I. Papakrivopoulos , J. Parshook , N. Pastika , M. Paulini , P. Paulitsch , T. Peltola , R. Pereira Gomes , H. Perkins , P. Petiot , F. Pitters , F. Pitters , H. Prosper , M. Prvan , I. Puljak , T. Quast , R. Quinn , M. Quinnan , K. Rapacz , L. Raux , G. Reichenbach , M. Reinecke , M. Revering , A. Rodriguez , T. Romanteau , A. Rose , M. Rovere , A. Roy , P. Rubinov , R. Rusack , A. E. Simsek , U. Sozbilir , O. M. Sahin , A. Sanchez , R. Saradhy , T. Sarkar , M. A. Sarkisla , J. B. Sauvan , I. Schmidt , M. Schmitt , E. Scott , C. Seez , F. Sefkow , S. Sharma , I. Shein , A. Shenai , R. Shukla , E. Sicking , P. Sieberer , Y. Sirois , V. Smirnov , E. Spencer , A. Steen , J. Strait , T. Strebler , N. Strobbe , J. W. Su , E. Sukhov , L. Sun , M. Sun , C. Syal , B. Tali , U. G. Tok , A. Kayis Topaksu , C. L. Tan , I. Tastan , T. Tatli , R. Thaus , S. Tekten , D. Thienpont , T. Pierre-Emile , E. Tiras , M. Titov , D. Tlisov , J. Troska , Z. Tsamalaidze , G. Tsipolitis , A. Tsirou , N. Tyurin , S. Undleeb , D. Urbanski , V. Ustinov , A. Uzunian , M. van de Klundert , J. Varela , M. Velasco , M. Vicente Barreto Pinto , P. M. da Silva , T. Virdee , R. Vizinho de Oliveira , J. Voelker , E. Voirin , Z. Wang , X. Wang , F. Wang , M. Wayne , S. N. Webb , M. Weinberg , A. Whitbeck , D. White , R. Wickwire , J. S. Wilson , H. Y. Wu , L. Wu , C. H Yeh , R. Yohay , G. B. Yu , S. S. Yu , D. Yu , F. Yumiceva , A. Zacharopoulou , N. Zamiatin , A. Zarubin , S. Zenz , H. Zhang , J. Zhang

This paper introduces OPTIMUM-DERAM, a highly consistent, scalable, secure, and decentralized shared memory solution. Traditional distributed shared memory implementations offer multi-object support by multi-threading a single object memory…

分布式、并行与集群计算 · 计算机科学 2026-01-21 Nicolas Nicolaou , Kishori M. Konwar , Moritz Grundei , Aleksandr Bezobchuk , Muriel Médard , Sriram Vishwanath

The goal of high-utility sequential pattern mining (HUSPM) is to efficiently discover profitable or useful sequential patterns in a large number of sequences. However, simply being aware of utility-eligible patterns is insufficient for…

人工智能 · 计算机科学 2022-10-28 Lili Chen , Wensheng Gan , Chien-Ming Chen

Just as in eukaryotes, high-throughput chromosome conformation capture (Hi-C) data have revealed nested organizations of bacterial chromosomes into overlapping interaction domains. In this chapter, we present a multiscale analysis framework…

基因组学 · 定量生物学 2020-10-06 Nelle Varoquaux , Virginia S. Lioy , Frédéric Boccard , Ivan Junier