相关论文: Coinami: A Cryptocurrency with DNA Sequence Alignm…
With small-scale quantum processors transitioning from experimental physics labs to industrial products, these processors allow us to efficiently compute important algorithms in various fields. In this paper, we propose a quantum algorithm…
The set of distributed ledger architectures known as blockchain is best known for cryptocurrency applications such as Bitcoin and Ethereum. These permissionless block chains are showing the potential to be disruptive to the financial…
Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to…
Reference-guided DNA sequencing and alignment is an important process in computational molecular biology. The amount of DNA data grows very fast, and many new genomes are waiting to be sequenced while millions of private genomes need to be…
An ideal signature material and method, which can be used to prove the authenticity of a physical item and against forgery, should be immune to the fast developments in digital and engineering technologies. Herein, the design of signature…
We deploy and demonstrate the CoinTossX low-latency, high-throughput, open-source matching engine with orders sent using the Julia and Python languages. We show how this can be deployed for small-scale local desk-top testing and discuss a…
Despite all the progress in quantum technologies over the last decade, there is still a dearth of practical applications for quantum computers with a small number of noisy qubits. The effort to show quantum supremacy has been largely…
Recently, there has been a remarkable amount of research being done in both, the fields of Blockchain and Internet of Things (IoT). Blockchain technology synergises well with IoT, solving key problems such as privacy, concerns with…
Bitcoin is the first fully-decentralized permissionless blockchain protocol to achieve a high level of security, but at the expense of poor throughput and latency. Scaling the performance of Bitcoin has a been a major recent direction of…
Hardware Transactional Memory (HTM) allows lock-free programming as easy as with traditional coarse-grain locks or similar, while benefiting from the performance advantages of fine-grained locking. Many HTM implementations have been…
Recent advances in quantum computing pose a serious threat on the security of widely used public-key cryptosystems. Thus, new post-quantum cryptographic algorithms have been proposed as part of the associated US NIST process to enable…
Throughput limitations of existing blockchain architectures are one of the most significant hurdles for their wide-spread adoption. Attempts to address this challenge include layer-2 solutions, such as Bitcoin's Lightning or Ethereum's…
We argue that the current POW based consensus algorithm of the Bitcoin network suffers from a fundamental economic discrepancy between the real world transaction (txn) costs incurred by miners and the wealth that is being transacted. Put…
Bitcoin is the most successful cryptocurrency so far. This is mainly due to its novel consensus algorithm, which is based on proof-of-work combined with a cryptographically-protected data structure and a rewarding scheme that incentivizes…
In large-scale distributed computing clusters, such as Amazon EC2, there are several types of "system noise" that can result in major degradation of performance: bottlenecks due to limited communication bandwidth, latency due to straggler…
Summary: HTSeq 2.0 provides a more extensive API including a new representation for sparse genomic data, enhancements in htseq-count to suit single cell omics, a new script for data using cell and molecular barcodes, improved documentation,…
To better understand DNA's 3D folding in cell nuclei, researchers developed chromosome capture methods such as Hi-C that measure the contact frequencies between all DNA segment pairs across the genome. As Hi-C data sets often are massive,…
The state-of-the-art for auditing and reproducing scientific applications on high-performance computing (HPC) systems is through a data provenance subsystem. While recent advances in data provenance lie in reducing the performance overhead…
Human genomic data carry unique information about an individual and offer unprecedented opportunities for healthcare. The clinical interpretations derived from large genomic datasets can greatly improve healthcare and pave the way for…
PHICOIN (PHI) is a high-performance cryptocurrency based on the Proof-of-Work (PoW) mechanism. It aims to provide ordinary users with decentralized participation opportunities through an improved and innovative mining algorithm and fair…