相关论文: Calibration and GEANT4 Simulations of the Phase II…
Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…
Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue…
Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…
Proton radiotherapy promises accurate dose delivery to a tumor and minimal dose deposition to all other tissues. However, in practice the planned dose distribution may not conform to the actual one due to noisy data and different types of…
The distribution of the prompt gamma emissions induced by proton interactions in a target material carries information concerning the proton range and target composition. In order to image prompt gamma we present different approaches. The…
PET imaging is a non-invasive technique for particle range verification in proton therapy. It is based on measuring the beta+ annihilations caused by nuclear interactions of the protons in the patient. In this work we present measurements…
Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient…
External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT…
Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…
The Resistive Plate Chambers (RPC) are low-cost charged-particle detectors with good timing resolution and potentially good spatial resolution. Using RPC as gamma detector provides an opportunity for application in positron emission…
Computer tomography is one of the most promising new methods to image abnormal tissues inside the human body. Tomography is also used to position the patient accurately before radiation therapy. Hadron therapy for treating cancer has become…
The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…
A prototype of proton counter was developed by the University and the National Institute for Nuclear Physics of Torino to be used as online fluence beam monitor in particle therapy. The single particle identification approach aims at…
Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…
The advanced imaging and delivery techniques in proton therapy allow conformal high-dose irradiation of the target volume with high accuracy using pencil beam scanning or beam shaping apertures. These irradiation methods increasingly…
Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…
For dose calculations in ion beam therapy, it is vital to accurately determine the relative stopping power (RSP) distribution within the treated volume. Currently, RSP values are extrapolated from Hounsfield units (HU), measured with x-ray…
Enhanced-accuracy ion-range verification in real time shall enable a significant step forward in the use of therapeutic ion beams. Positron-emission tomography (PET) and prompt-gamma imaging (PGI) are two of the most promising and…
Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…
Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…