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Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be…

机器学习 · 计算机科学 2020-05-26 Cooper J. Mellema , Alex Treacher , Kevin P. Nguyen , Albert Montillo

This paper studies the problem of detecting anomalous graphs using a machine learning model trained on only normal graphs, which has many applications in molecule, biology, and social network data analysis. We present a self-discriminative…

机器学习 · 计算机科学 2023-10-11 Jinyu Cai , Yunhe Zhang , Jicong Fan

This manuscript considers the following "graph classification" question: given a collection of graphs and associated classes, how can one predict the class of a newly observed graph? To address this question we propose a statistical model…

应用统计 · 统计学 2012-07-13 Joshua T. Vogelstein , William R. Gray , R. Jacob Vogelstein , Carey E. Priebe

Graphical models are commonly used to represent conditional dependence relationships between variables. There are multiple methods available for exploring them from high-dimensional data, but almost all of them rely on the assumption that…

机器学习 · 统计学 2020-04-22 Tianxi Li , Cheng Qian , Elizaveta Levina , Ji Zhu

Anatomical brain parcellations dominate rs-fMRI-based Autism Spectrum Disorder (ASD) classification, yet their rigid boundaries may fail to capture the idiosyncratic connectivity patterns that characterise ASD. We present a graph-based deep…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Syeda Hareem Madani , Noureen Bibi , Adam Rafiq Jeraj , Sumra Khan , Anas Zafar , Rizwan Qureshi

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

统计方法学 · 统计学 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Directed graphs naturally model systems with asymmetric, ordered relationships, essential to applications in biology, transportation, social networks, and visual understanding. Generating such graphs enables tasks such as simulation, data…

机器学习 · 计算机科学 2026-02-20 Alba Carballo-Castro , Manuel Madeira , Yiming Qin , Dorina Thanou , Pascal Frossard

Neural networks are often represented as graphs of connections between neurons. However, despite their wide use, there is currently little understanding of the relationship between the graph structure of the neural network and its…

机器学习 · 计算机科学 2020-08-28 Jiaxuan You , Jure Leskovec , Kaiming He , Saining Xie

A number of network structural characteristics have recently been the subject of particularly intense research, including degree distributions, community structure, and various measures of vertex centrality, to mention only a few. Vertices…

社会与信息网络 · 计算机科学 2016-03-23 Igor Trpevski , Tamara Dimitrova , Tommy Boshkovski , Ljupco Kocarev

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

图像与视频处理 · 电气工程与系统科学 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Inferring synaptic connectivity from neural population activity is a fundamental challenge in computational neuroscience, complicated by partial observability and mismatches between inference models and true circuit dynamics. In this study,…

神经元与认知 · 定量生物学 2025-10-28 Kijung Yoon

Graph databases have been the subject of significant research and development. Problems such as modularity, centrality, alignment, and clustering have been formalized and solved in various application contexts. In this paper, we focus on…

社会与信息网络 · 计算机科学 2019-08-09 Vikram Ravindra , Huda Nassar , David F. Gleich , Ananth Grama

Functional Magnetic Resonance Imaging (fMRI) provides useful insights into the brain function both during task or rest. Representing fMRI data using correlation matrices is found to be a reliable method of analyzing the inherent…

机器学习 · 计算机科学 2025-01-29 Yicheng Leng , Syed Muhammad Anwar , Islem Rekik , Sen He , Eung-Joo Lee

Gaussian Graphical Models (GGM) are popularly used in neuroimaging studies based on fMRI, EEG or MEG to estimate functional connectivity, or relationships between remote brain regions. In multi-subject studies, scientists seek to identify…

统计方法学 · 统计学 2017-05-01 Manjari Narayan , Genevera I. Allen , Steffie Tomson

Background: Alzheimer's disease and related dementias (ADRD) ranks as the sixth leading cause of death in the US, underlining the importance of accurate ADRD risk prediction. While recent advancement in ADRD risk prediction have primarily…

机器学习 · 计算机科学 2024-06-11 Xinyue Hu , Zenan Sun , Yi Nian , Yichen Wang , Yifang Dang , Fang Li , Jingna Feng , Evan Yu , Cui Tao

Statistical techniques are needed to analyse data structures with complex dependencies such that clinically useful information can be extracted. Individual-specific networks, which capture dependencies in complex biological systems, are…

统计方法学 · 统计学 2023-08-30 Mariella Gregorich , Sean L. Simpson , Georg Heinze

The central nervous system is composed of many individual units -- from cells to areas -- that are connected with one another in a complex pattern of functional interactions that supports perception, action, and cognition. One natural and…

神经元与认知 · 定量生物学 2017-04-03 Ann E. Sizemore , Danielle S. Bassett

The application of graph theory to model the complex structure and function of the brain has shed new light on its organization and function, prompting the emergence of network neuroscience. Despite the tremendous progress that has been…

信号处理 · 电气工程与系统科学 2020-09-29 Giulia Lioi , Vincent Gripon , Abdelbasset Brahim , François Rousseau , Nicolas Farrugia

Exploiting the wealth of imaging and non-imaging information for disease prediction tasks requires models capable of representing, at the same time, individual features as well as data associations between subjects from potentially large…

Network topology inference is a prominent problem in Network Science. Most graph signal processing (GSP) efforts to date assume that the underlying network is known, and then analyze how the graph's algebraic and spectral characteristics…

信号处理 · 电气工程与系统科学 2019-05-22 Gonzalo Mateos , Santiago Segarra , Antonio G. Marques , Alejandro Ribeiro