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The matched case-control design, up until recently mostly pertinent to epidemiological studies, is becoming customary in biomedical applications as well. For instance, in omics studies, it is quite common to compare cancer and healthy…

统计方法学 · 统计学 2024-02-05 Vera Djordjilović , Erica Ponzi , Therese Haugdahl Nøst , Magne Thoresen

Graphical models are a powerful tool in modelling and analysing complex biological associations in high-dimensional data. The R-package netgwas implements the recent methodological development on copula graphical models to (i) construct…

应用统计 · 统计学 2023-01-27 Pariya Behrouzi , Danny Arends , Ernst C. Wit

Normative and task-driven theories offer powerful top-down explanations for biological systems, yet the goals of quantitatively arbitrating between competing theories, and utilizing them as inductive biases to improve data-driven fits of…

人工智能 · 计算机科学 2025-09-30 Bahti Zakirov , Gašper Tkačik

The R package bsvars provides a wide range of tools for empirical macroeconomic and financial analyses using Bayesian Structural Vector Autoregressions. It uses frontier econometric techniques and C++ code to ensure fast and efficient…

计量经济学 · 经济学 2025-04-17 Tomasz Woźniak

Empirical claims often rely on one population, design, and analysis. Many-analysts, multiverse, and robustness studies expose how results can vary across plausible analytic choices. Synthesizing these results, however, is nontrivial as all…

统计方法学 · 统计学 2025-11-24 František Bartoš , Suzanne Hoogeveen , Alexandra Sarafoglou , Samuel Pawel

In this paper, we deduce a new multivariate regression model designed to fit correlated binary data. The multivariate distribution is derived from a Bernoulli mixed model with a nonnormal random intercept on the marginal approach. The…

统计方法学 · 统计学 2024-06-10 Lizandra C. Fabio , Vanessa Barros , Cristian Villegas , Jalmar M. F. Carrasco

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

统计方法学 · 统计学 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

Analyzing data from multiple neuroimaging studies has great potential in terms of increasing statistical power, enabling detection of effects of smaller magnitude than would be possible when analyzing each study separately and also allowing…

Meta-analysis is a powerful tool to synthesize findings from multiple studies. The normal-normal random-effects model is widely used to account for between-study heterogeneity. However, meta-analysis of sparse data, which may arise when the…

统计方法学 · 统计学 2024-06-10 Taojun Hu , Yi Zhou , Satoshi Hattori

There has been increased interest in the use of historical data to formulate informative priors in regression models. While many such priors for incorporating historical data have been proposed, adoption is limited due to access to…

统计方法学 · 统计学 2025-06-26 Ethan M. Alt , Xinxin Chen , Luiz M. Carvalho , Joseph G. Ibrahim

Recent advances in computational methods for intractable models have made network data increasingly amenable to statistical analysis. Exponential random graph models (ERGMs) emerged as one of the main families of models capable of capturing…

统计计算 · 统计学 2021-04-07 Alberto Caimo , Lampros Bouranis , Robert Krause , Nial Friel

Surveys are an important research tool, providing unique measurements on subjective experiences such as sentiment and opinions that cannot be measured by other means. However, because survey data is collected from a self-selected group of…

统计计算 · 统计学 2023-07-14 Tal Sarig , Tal Galili , Roee Eilat

The Bergm package provides a comprehensive framework for Bayesian inference using Markov chain Monte Carlo (MCMC) algorithms. It can also supply graphical Bayesian goodness-of-fit procedures that address the issue of model adequacy. The…

统计计算 · 统计学 2017-03-28 Alberto Caimo , Nial Friel

This is a short description and basic introduction to the Integrated nested Laplace approximations (INLA) approach. INLA is a deterministic paradigm for Bayesian inference in latent Gaussian models (LGMs) introduced in Rue et al. (2009).…

统计计算 · 统计学 2019-07-03 Sara Martino , Andrea Riebler

Publication bias (PB) poses a significant threat to meta-analysis, as studies yielding notable results are more likely to be published in scientific journals. Sensitivity analysis provides a flexible method to address PB and to examine the…

应用统计 · 统计学 2024-06-07 Taojun Hu , Yi Zhou , Xiao-Hua Zhou , Satoshi Hattori

Robust statistical data modelling under potential model mis-specification often requires leaving the parametric world for the nonparametric. In the latter, parameters are infinite dimensional objects such as functions, probability…

Standard random-effects meta-analysis relies heavily on the assumption that the underlying true effects are normally distributed. In the social sciences, where evidence synthesis increasingly involves large, highly heterogeneous datasets,…

统计方法学 · 统计学 2026-05-01 Daihe Sui , Elizabeth Tipton

The past decade has seen an explosion of research in causal mediation analysis. However, most analytic tools developed so far rely on frequentist methods which may not be robust in the case of small sample sizes. In this paper, we propose a…

统计计算 · 统计学 2023-07-19 Belay B Yimer , Mark Lunt , Marcus Beasley , Gary J Macfarlane , John McBeth

Bayesian penalized regression techniques, such as the Bayesian lasso and the Bayesian horseshoe estimator, have recently received a significant amount of attention in the statistics literature. However, software implementing…

统计计算 · 统计学 2016-12-21 Enes Makalic , Daniel F. Schmidt

We introduce cyclinbayes, an open-source R package for discovering linear causal relationships with both acyclic and cyclic structures. The package employs scalable Bayesian approaches with spike-and-slab priors to learn directed acyclic…

统计计算 · 统计学 2026-02-25 Robert Lee , Raymond K. W. Wong , Yang Ni