相关论文: Learning Linguistic Biomarkers for Predicting Mild…

Advanced neural interfaces are transforming applications ranging from neuroscience research to diagnostic tools (for mental state recognition, tremor and seizure detection) as well as prosthetic devices (for motor and communication…

Speech-based digital biomarkers represent a scalable, non-invasive frontier for the early identification of Mild Cognitive Impairment (MCI). However, the development of robust diagnostic models remains impeded by acute clinical data…

Detecting Mild Cognitive Impairment from picture descriptions is critical yet challenging, especially in multilingual and multiple picture settings. Prior work has primarily focused on English speakers describing a single picture (e.g., the…

Mild traumatic brain injury is a growing public health problem with an estimated incidence of over 1.7 million people annually in US. Diagnosis is based on clinical history and symptoms, and accurate, concrete measures of injury are…

We present a novel family of language model (LM) estimation techniques named Sparse Non-negative Matrix (SNM) estimation. A first set of experiments empirically evaluating it on the One Billion Word Benchmark shows that SNM $n$-gram LMs…

How the brain supports language across different languages is a basic question in neuroscience and a useful test for multilingual artificial intelligence. Neuroimaging has identified language-responsive brain regions across languages, but…

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

Machine learning in medicine leverages the wealth of healthcare data to extract knowledge, facilitate clinical decision-making, and ultimately improve care delivery. However, ML models trained on datasets that lack demographic diversity…

Background: Patients with both diabetes mellitus (DM) and atrial fibrillation (AF) face elevated mortality in intensive care units (ICUs), yet models targeting this high-risk group remain limited. Objective: To develop an interpretable…

Understanding the relationship between mild cognitive impairment (MCI) and driving behavior is essential for enhancing road safety, particularly among older adults. This study introduces a novel approach by incorporating specific trip…

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant…

While deep learning-based Alzheimer's disease (AD) diagnosis has recently made significant advancements, particularly in predicting the conversion of mild cognitive impairment (MCI) to AD based on MRI images, there remains a critical gap in…

Predicting whether subjects with mild cognitive impairment (MCI) will convert to Alzheimer's disease is a significant clinical challenge. Longitudinal variations and complementary information inherent in longitudinal and multimodal data are…

Independent component analysis (ICA) of multi-subject functional magnetic resonance imaging (fMRI) data has proven useful in providing a fully multivariate summary that can be used for multiple purposes. ICA can identify patterns that can…

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…

Decoding human activity from EEG signals has long been a popular research topic. While recent studies have increasingly shifted focus from single-subject to cross-subject analysis, few have explored the model's ability to perform zero-shot…

The prediction of mild cognitive impairment (MCI) conversion to Alzheimer's disease (AD) is important for early treatment to prevent or slow the progression of AD. To accurately predict the MCI conversion to stable MCI or progressive MCI,…

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

The ageing population trend is correlated with an increased prevalence of acquired cognitive impairments such as dementia. Although there is no cure for dementia, a timely diagnosis helps in obtaining necessary support and appropriate…