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Purpose: To assess the utility of Laplacian fitting to describe the differences in hyperpolarized 13C urea T2 relaxation in ischemic and healthy rodent kidneys. Theory and Methods: Six rats with unilateral renal ischemia were investigated.…

The inhomogeneity of an electron spin ensemble as well as fluctuating environment acting upon individual spins drastically shorten the spin coherence time $T_2$ and hinder coherent spin manipulation. We show that this problem can be solved…

介观与纳米尺度物理 · 物理学 2021-10-13 V. V. Belykh , A. R. Korotneva , D. R. Yakovlev

[1-13C]pyruvate is the most widely used tracer for hyperpolarized metabolic magnetic resonance imaging, with profound applications in tumor and inflammation diagnosis as well as treatment monitoring. The most fundamental hurdle to broader…

Urea, NH2C(O)NH2, is a molecule of great importance in organic chemistry and biology. Two searches for urea in the interstellar medium were reported in the past, but neither were conclusive. We want to take advantage of the increased…

星系天体物理 · 物理学 2019-07-31 A. Belloche , R. T. Garrod , H. S. P. Müller , K. M. Menten , I. Medvedev , J. Thomas , Z. Kisiel

A wide variety of nuclear magnetic resonance experiments rely on the prediction and analysis of relaxation processes. Recently, innovative approaches have been introduced where the sample travels through a broad range of magnetic fields in…

We present results of Raman spectroscopic studies of urine to determine the suitability of near-infrared Raman spectroscopy for quantitative estimation of urinary urea. The Raman spectra were acquired from the urine samples with an inbuilt…

医学物理 · 物理学 2014-12-24 S. Kumar , S. K. Majumdar

Relaxometry studies in preterm and at-term newborns have provided insight into brain microstructure, thus opening new avenues for studying normal brain development and supporting diagnosis in equivocal neurological situations. However, such…

Understanding the origins of spin lifetimes in hybrid quantum systems is a matter of current importance in several areas of quantum information and sensing. Methods that spectrally map spin relaxation processes provide insight into their…

Purpose: A combined diffusion-relaxometry MR acquisition and analysis pipeline for in-vivo human placenta, which allows for exploration of coupling between T2* and apparent diffusion coefficient (ADC) measurements in a sub 10 minute scan…

Macroscopic spin ensembles in solids are powerful platforms for quantum sensing and precision metrology. A key challenge is controlling the nuclear spin population relaxation time $T_1$, which can become prohibitively long at cryogenic…

The purpose of this work is to develop a deep learning-based method for knee menisci segmentation in 3D ultrashort echo time (UTE) cones magnetic resonance (MR) imaging, and to automatically determine MR relaxation times, namely the T1,…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Michal Byra , Mei Wu , Xiaodong Zhang , Hyungseok Jang , Ya-Jun Ma , Eric Y Chang , Sameer Shah , Jiang Du

Pressure ulcers (PU) are known to be a high-cost disease with a risk of severe morbidity. This work evaluates a new clinical strategy based on an innovative medical device (Tongue Display Unit-TDU) that implements perceptive supplementation…

The objective of this study was to characterize hemodynamic changes during trans-vascular stimulation of the renal nerve and their dependence on stimulation parameters. We employed a stimulation catheter inserted in the right renal artery…

Multiexponential T2 (MET2) Relaxometry and Magnetization Transfer (MT) are among the most promising MRI-derived techniques for white matter (WM) characterization. Both techniques are shown to have histologically correlated sensitivity to…

医学物理 · 物理学 2019-03-26 Teresa Serradas Duarte , Noam Shemesh

We use charge sensing of Pauli blockade (including spin and isospin) in a two-electron 13C nanotube double quantum dot to measure relaxation and dephasing times. The relaxation time, T1, first decreases with parallel magnetic field then…

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

医学物理 · 物理学 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Several elements in the periodic table exhibit an interesting and often overlooked feature: They skip certain valence states which is discussed in the field of superconductivity to be in favor of fostering higher transition temperatures…

超导电性 · 物理学 2025-03-27 Yoshihiko Ihara , Masakazu Shimohashi , Markus Kriener

Radiofrequency (RF) pulses are a critical part of every MRI pulse sequence, and must be specifically designed for ultrashort echo time (UTE) and zero echo time (ZTE) acquisitions. When considering the behavior of RF pulses, most often…

医学物理 · 物理学 2024-02-27 Peder E. Z. Larson

We report on experiments that quantify the role of a central electronic spin as a relaxation source for nuclear spins in its nanoscale environment. Our strategy exploits hyperpolarization injection from the electron as a means to…

介观与纳米尺度物理 · 物理学 2024-02-27 William Beatrez , Arjun Pillai , Otto Janes , Dieter Suter , Ashok Ajoy

UTE (Ultrashort Echo Time) and ZTE (Zero Echo Time) sequences have been developed to detect short T2 relaxation signals coming from regions that are unable to be detected by conventional MRI methods. Due to the high dipole-dipole…

医学物理 · 物理学 2024-01-17 Soham Sharad More , Xiaoliang Zhang
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