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We propose a formal mathematical model for sparse representations and active dendrites in neocortex. Our model is inspired by recent experimental findings on active dendritic processing and NMDA spikes in pyramidal neurons. These…

神经元与认知 · 定量生物学 2016-05-16 Subutai Ahmad , Jeff Hawkins

As a follow-up tutorial article of [29], in this paper, we will introduce the basic compositional units of the human brain, which will further illustrate the cell-level bio-structure of the brain. On average, the human brain contains about…

神经元与认知 · 定量生物学 2019-06-06 Jiawei Zhang

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

神经元与认知 · 定量生物学 2012-03-06 Xuejuan Zhang , Jianfeng Feng

A pressing scientific challenge is to understand how brains work. Of particular interest is the neocortex,the part of the brain that is especially large in humans, capable of handling a wide variety of tasks including visual, auditory,…

神经与进化计算 · 计算机科学 2016-09-03 Peter U. Diehl , Matthew Cook

Sequential activation of neurons is a common feature of network activity during a variety of behaviors, including working memory and decision making. Previous network models for sequences and memory emphasized specialized architectures in…

神经元与认知 · 定量生物学 2016-03-16 Kanaka Rajan , Christopher D Harvey , David W Tank

Neocortical pyramidal neurons have many dendrites, and such dendrites are capable of, in isolation of one-another, generating a neuronal spike. It is also now understood that there is a large amount of dendritic growth during the first…

神经元与认知 · 定量生物学 2022-10-31 William B Levy , Robert A. Baxter

A model of the columnar functional organization of neocortical association areas is studied. The neuronal network is composed of many Hebbian autoassociators, or modules, each of which interacts with a relatively small number of the others.…

无序系统与神经网络 · 物理学 2020-05-14 Carlo Fulvi Mari

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

神经元与认知 · 定量生物学 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

生物物理 · 物理学 2017-05-09 Marat M. Rvachev

Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

机器学习 · 计算机科学 2025-09-03 Lucie Fontaine , Frédéric Alexandre

In the traditional understanding of the neocortex, sensory information flows up a hierarchy of regions, with each level processing increasingly complex features. Information also flows down the hierarchy via a different set of connections.…

神经元与认知 · 定量生物学 2025-07-09 Jeff Hawkins , Niels Leadholm , Viviane Clay

Jeff Hawkins and his colleagues in Numenta have proposed the thousand-brains system. This is a model of the structure and operation of the neocortex and is under investigation as a new form of artificial intelligence. In their study,…

神经元与认知 · 定量生物学 2025-06-30 Hajime Kawakami

The brain is targeted for processing temporal sequence information. It remains largely unclear how the brain learns to store and retrieve sequence memories. Here, we study how recurrent networks of binary neurons learn sequence attractors…

神经与进化计算 · 计算机科学 2024-04-04 Yao Lu , Si Wu

We present an account of neuroplasticity with respect to cell-internal processing pathways in relation to membrane and synaptic plasticity. We think traditional synapse-centric, weight-based models of memorization are not sufficient or…

神经元与认知 · 定量生物学 2026-04-27 Gabriele Scheler

Human brains respond to semantic features of presented stimuli with different neurons. It is then curious whether modern deep neural networks admit a similar behavior pattern. Specifically, this paper finds a small cluster of neurons in a…

计算机视觉与模式识别 · 计算机科学 2023-03-10 Zhiheng Liu , Ruili Feng , Kai Zhu , Yifei Zhang , Kecheng Zheng , Yu Liu , Deli Zhao , Jingren Zhou , Yang Cao

A basic question within the emerging field of mechanistic interpretability is the degree to which neural networks learn the same underlying mechanisms. In other words, are neural mechanisms universal across different models? In this work,…

While deep neural networks take loose inspiration from neuroscience, it is an open question how seriously to take the analogies between artificial deep networks and biological neuronal systems. Interestingly, recent work has shown that deep…

神经元与认知 · 定量生物学 2018-05-31 William Lotter , Gabriel Kreiman , David Cox

Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…

神经元与认知 · 定量生物学 2017-04-11 Jordan Guergiuev , Timothy P. Lillicrap , Blake A. Richards

Deep learning techniques are increasingly being adopted for classification tasks over the past decade, yet explaining how deep learning architectures can achieve state-of-the-art performance is still an elusive goal. While all the training…

机器学习 · 计算机科学 2021-10-12 Sakib Mostafa , Debajyoti Mondal

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

神经元与认知 · 定量生物学 2020-12-02 Hui Wei
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