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Pneumonia is the leading cause of death among young children and one of the top mortality causes worldwide. The pneumonia detection is usually performed through examine of chest X-ray radiograph by highly-trained specialists. This process…

图像与视频处理 · 电气工程与系统科学 2020-12-04 Tatiana Gabruseva , Dmytro Poplavskiy , Alexandr A. Kalinin

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

统计方法学 · 统计学 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

Machine learning has become ubiquitous and a key technology on mining electronic health records (EHRs) for facilitating clinical research and practice. Unsupervised machine learning, as opposed to supervised learning, has shown promise in…

Providing accurate and reliable predictions about the future of an epidemic is an important problem for enabling informed public health decisions. Recent works have shown that leveraging data-driven solutions that utilize advances in deep…

机器学习 · 计算机科学 2023-11-21 Harshavardhan Kamarthi , B. Aditya Prakash

Deep learning models detect pneumonia from chest X-rays with high accuracy, but the performance declines under domain shifts caused by differences in devices, patients, or institutions. We present PneumoNet, a domain-incremental learning…

机器学习 · 计算机科学 2026-05-20 Danu Kim

We consider the problem of model choice for stochastic epidemic models given partial observation of a disease outbreak through time. Our main focus is on the use of Bayes factors. Although Bayes factors have appeared in the epidemic…

统计计算 · 统计学 2017-10-16 Muteb Alharthi , Theodore Kypraios , Philip D. O'Neill

The human microbiome is a complex ecological system, and describing its structure and function under different environmental conditions is important from both basic scientific and medical perspectives. Viewed through a biostatistical lens,…

应用统计 · 统计学 2017-11-17 Kris Sankaran , Susan P. Holmes

Lung disease poses a substantial global health challenge, with pneumonia being a prevalent concern. This research focuses on leveraging deep learning techniques to detect and assess pneumonia, addressing two interconnected objectives.…

计算机视觉与模式识别 · 计算机科学 2025-02-11 S Kumar Reddy Mallidi

Spatio-temporal prediction of levels of an environmental exposure is an important problem in environmental epidemiology. Our work is motivated by multiple studies on the spatio-temporal distribution of mobile source, or traffic related,…

应用统计 · 统计学 2014-11-14 Nikolay Bliznyuk , Christopher J. Paciorek , Joel Schwartz , Brent Coull

We propose a Bayesian nonparametric (BNP) approach to causal inference using observational data consisting of outcome, treatment, and a set of confounders. The conditional distribution of the outcome given treatment and confounders is…

统计方法学 · 统计学 2025-12-01 Yongseok Hur , Joonhyuk Jung , Juhee Lee

Pneumonia is a serious global health problem, contributing to high morbidity and mortality, especially in areas with limited diagnostic tools and healthcare resources. This study develops a Convolutional Neural Network (CNN) based on deep…

图像与视频处理 · 电气工程与系统科学 2026-02-17 Hadi Almohab

As advancements in technology and medicine are being made, many countries are still unable to access quality medical care due to cost and lack of qualified medical personnel. This discrepancy in healthcare has caused many preventable…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Kyler Larsen

Localization and characterization of diseases like pneumonia are primary steps in a clinical pipeline, facilitating detailed clinical diagnosis and subsequent treatment planning. Additionally, such location annotated datasets can provide a…

图像与视频处理 · 电气工程与系统科学 2021-10-08 Riddhish Bhalodia , Ali Hatamizadeh , Leo Tam , Ziyue Xu , Xiaosong Wang , Evrim Turkbey , Daguang Xu

The condition of parameter identifiability is essential for the consistency of all estimators and is often challenging to prove. As a consequence, this condition is often assumed for simplicity although this may not be straightforward to…

统计理论 · 数学 2016-07-21 Stéphane Guerrier , Roberto Molinari

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

统计方法学 · 统计学 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe

The analysis of count data is commonly done using Poisson models. Negative binomial models are a straightforward and readily motivated generalization for the case of overdispersed data, i.e., when the observed variance is greater than…

统计方法学 · 统计学 2016-01-06 Christian Röver , Stefan Andreas , Tim Friede

The appropriateness of the Poisson model is frequently challenged when examining spatial count data marked by unbalanced distributions, over-dispersion, or under-dispersion. Moreover, traditional parametric models may inadequately capture…

统计方法学 · 统计学 2025-03-26 Mahsa Nadifar , Andriette Bekker , Mohammad Arashi , Abel Ramoelo

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

统计方法学 · 统计学 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

Addressing the challenge of scaling-up epidemiological inference to complex and heterogeneous models, we introduce Poisson Approximate Likelihood (PAL) methods. In contrast to the popular ODE approach to compartmental modelling, in which a…

统计方法学 · 统计学 2023-06-05 Michael Whitehouse , Nick Whiteley , Lorenzo Rimella

A much studied issue is the extent to which the confidence scores provided by machine learning algorithms are calibrated to ground truth probabilities. Our starting point is that calibration is seemingly incompatible with class weighting, a…

机器学习 · 计算机科学 2022-08-02 Andrew Caplin , Daniel Martin , Philip Marx