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相关论文: Monitoring Potential Drug Interactions and Reactio…

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Illicit drug trafficking via social media sites such as Instagram has become a severe problem, thus drawing a great deal of attention from law enforcement and public health agencies. How to identify illicit drug dealers from social media…

机器学习 · 计算机科学 2021-08-24 Chuanbo Hu , Minglei Yin , Bin Liu , Xin Li , Yanfang Ye

Illicit drug trade via social media sites, especially photo-oriented Instagram, has become a severe problem in recent years. As a result, tracking drug dealing and abuse on Instagram is of interest to law enforcement agencies and public…

社会与信息网络 · 计算机科学 2016-05-26 Xitong Yang , Jiebo Luo

The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…

定量方法 · 定量生物学 2020-09-02 Ricky Wang

Drug-drug interactions (DDIs) are a major concern in polypharmacy. Public databases often provide only qualitative descriptions without pharmacokinetic context. We present an interactive web tool that integrates 191,541 descriptive DDI…

定量方法 · 定量生物学 2025-08-13 Nadezhda Diadkina

Drug use by people is on the rise and is of great interest to public health agencies and law enforcement agencies. As found by the National Survey on Drug Use and Health, 20 million Americans aged 12 years or older consumed illicit drugs in…

社会与信息网络 · 计算机科学 2016-04-26 Yiheng Zhou , Numair Sani , Chia-Kuei Lee , Jiebo Luo

According to NSDUH (National Survey on Drug Use and Health), 20 million Americans consumed drugs in the past few 30 days. Combating illicit drug use is of great interest to public health and law enforcement agencies. Despite of the…

社会与信息网络 · 计算机科学 2016-11-28 Yiheng Zhou , Numair Sani , Jiebo Luo

Dietary supplements are used by a large portion of the population, but information on their pharmacologic interactions is incomplete. To address this challenge, we present SUPP.AI, an application for browsing evidence of supplement-drug…

计算与语言 · 计算机科学 2020-07-08 Lucy Lu Wang , Oyvind Tafjord , Arman Cohan , Sarthak Jain , Sam Skjonsberg , Carissa Schoenick , Nick Botner , Waleed Ammar

Social media has grown to be a crucial information source for pharmacovigilance studies where an increasing number of people post adverse reactions to medical drugs that are previously unreported. Aiming to effectively monitor various…

机器学习 · 计算机科学 2018-02-19 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu

Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc. While each one of these…

计算机与社会 · 计算机科学 2015-07-21 Juan M. Banda , Tobias Kuhn , Nigam H. Shah , Michel Dumontier

Understanding the interaction between different drugs (drug-drug interaction or DDI) is critical for ensuring patient safety and optimizing therapeutic outcomes. Existing DDI datasets primarily focus on textual information, overlooking…

机器学习 · 计算机科学 2025-06-03 Tung-Lam Ngo , Ba-Hoang Tran , Duy-Cat Can , Trung-Hieu Do , Oliver Y. Chén , Hoang-Quynh Le

Drug-drug interactions (DDIs) are a major concern in clinical practice, as they can lead to reduced therapeutic efficacy or severe adverse effects. Traditional computational approaches often struggle to capture the complex relationships…

机器学习 · 计算机科学 2025-08-27 Hongbo Liu , Siyi Li , Zheng Yu

Adverse drug reaction (ADR) prediction plays a crucial role in both health care and drug discovery for reducing patient mortality and enhancing drug safety. Recently, many studies have been devoted to effectively predict the drug-ADRs…

信息检索 · 计算机科学 2023-08-08 Haoxuan Li , Taojun Hu , Zetong Xiong , Chunyuan Zheng , Fuli Feng , Xiangnan He , Xiao-Hua Zhou

Minimizing adverse reactions caused by drug-drug interactions has always been a momentous research topic in clinical pharmacology. Detecting all possible interactions through clinical studies before a drug is released to the market is a…

人工智能 · 计算机科学 2018-03-13 Meng Wang

Population-scale drug prescription data linked with adverse drug reaction (ADR) data supports the fitting of models large enough to detect drug use and ADR patterns that are not detectable using traditional methods on smaller datasets.…

定量方法 · 定量生物学 2021-06-02 Tengel Ekrem Skar , Einar Holsbø , Kristian Svendsen , Lars Ailo Bongo

Complex or co-existing diseases are commonly treated using drug combinations, which can lead to higher risk of adverse side effects. The detection of polypharmacy side effects is usually done in Phase IV clinical trials, but there are still…

机器学习 · 统计学 2019-05-03 Andreea Deac , Yu-Hsiang Huang , Petar Veličković , Pietro Liò , Jian Tang

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

机器学习 · 计算机科学 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

With the increase in popularity of deep learning models for natural language processing (NLP) tasks, in the field of Pharmacovigilance, more specifically for the identification of Adverse Drug Reactions (ADRs), there is an inherent need for…

信息检索 · 计算机科学 2020-04-01 Ramya Tekumalla , Juan M. Banda

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

计算与语言 · 计算机科学 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

Substance use disorders (SUDs) are a growing concern globally, necessitating enhanced understanding of the problem and its trends through data-driven research. Social media are unique and important sources of information about SUDs,…

计算与语言 · 计算机科学 2024-05-13 Yao Ge , Sudeshna Das , Karen O'Connor , Mohammed Ali Al-Garadi , Graciela Gonzalez-Hernandez , Abeed Sarker

The occurrence of drug-drug-interactions (DDI) from multiple drug dispensations is a serious problem, both for individuals and health-care systems, since patients with complications due to DDI are likely to reenter the system at a costlier…

社会与信息网络 · 计算机科学 2020-01-03 Rion Brattig Correia , Luciana P. de Araújo , Mauro M. Mattos , Luis M. Rocha
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