相关论文: Orthologs from maxmer sequence context

We study a linear contextual optimization problem where a decision maker has access to historical data and contextual features to learn a cost prediction model aimed at minimizing decision error. We adopt the predict-then-optimize framework…

The Spliced Alignment Problem (SAP) that consists in finding an optimal semi-global alignment of a spliced RNA sequence on an unspliced genomic sequence has been largely considered for the prediction and the annotation of gene structures in…

Ontology Matching (OM), is a critical task in knowledge integration, where aligning heterogeneous ontologies facilitates data interoperability and knowledge sharing. Traditional OM systems often rely on expert knowledge or predictive…

Large ontologies still pose serious challenges to state-of-the-art ontology alignment systems. In the paper we present an approach that combines a lexical index, a neural embedding model and locality modules to effectively divide an input…

Ontology alignment, a critical process in the Semantic Web for detecting relationships between different ontologies, has traditionally focused on identifying so-called "simple" 1-to-1 relationships through class labels and properties…

Ontology alignment is widely-used to find the correspondences between different ontologies in diverse fields.After discovering the alignments,several performance scores are available to evaluate them.The scores typically require the…

Existing ordinal embedding methods usually follow a two-stage routine: outlier detection is first employed to pick out the inconsistent comparisons; then an embedding is learned from the clean data. However, learning in a multi-stage manner…

Large language models (LLMs) call for extension of context to handle many critical applications. However, the existing approaches are prone to expensive costs and inferior quality of context extension. In this work, we proposeExtensible…

Neural sequence-to-sequence systems deliver state-of-the-art performance for automatic speech recognition. When using appropriate modeling units, e.g., byte-pair encoding, these systems are in principle open vocabulary systems. In practice,…

Modern machine learning models typically represent inputs as fixed points in a high-dimensional embedding space. While this approach has been proven powerful for a wide range of downstream tasks, it fundamentally differs from the way humans…

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

We present ReMatch, a framework that leverages the generative strength of MLLMs for multimodal retrieval. Previous approaches treated an MLLM as a simple encoder, ignoring its generative nature, and under-utilising its compositional…

Modern large language models (LLMs) excel at tasks that require storing and retrieving knowledge, such as factual recall and question answering. Transformers are central to this capability because they can encode information during training…

Identifying evolutionary correspondences between cell types across species is a fundamental challenge in comparative genomics and evolutionary biology. Existing approaches often rely on either reference-based matching, which imposes…

Homologous gene shuffling between DNA promotes genetic diversity and is an important pathway for DNA repair. For this to occur, homologous genes need to find and recognize each other. However, despite its central role in homologous…

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Applying machine learning algorithms to large-scale, text-based corpora (embeddings) presents a unique opportunity to investigate at scale how human semantic knowledge is organized and how people use it to judge fundamental relationships,…

Graph matching, also known as network alignment, refers to finding a bijection between the vertex sets of two given graphs so as to maximally align their edges. This fundamental computational problem arises frequently in multiple fields…

When ontologies reach a certain size and complexity, faults such as inconsistencies, unsatisfiable classes or wrong entailments are hardly avoidable. Locating the incorrect axioms that cause these faults is a hard and time-consuming task.…

Evolutionary scenarios describing the evolution of a family of genes within a collection of species comprise the mapping of the vertices of a gene tree $T$ to vertices and edges of a species tree $S$. The relative timing of the last common…