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Ion-mediated interaction is critical to the structure and stability of nucleic acids. Recent experiments suggest that the multivalent ion-induced aggregation of double-stranded (ds) RNAs and DNAs may strongly depend on the topological…

生物物理 · 物理学 2015-07-13 Yuan-Yan Wu , Zhong-Liang Zhang , Jin-Si Zhang , Xiao-Long Zhu , Zhi-Jie Tan

There are two approaches to describing DNA-ions interactions. The physical approach is an analysis of electrostatic interactions between ions and charges on the DNA molecule. The coordination chemistry approach is a search for modes of…

生物大分子 · 定量生物学 2025-10-29 Elena A. Zubova , Ivan A. Strelnikov

The radiation-induced damages in bio-molecules are ubiquitous processes in radiotherapy, radio-biology and critical to space-projects. In this study we present a precise quantification of the fragmentation mechanisms of deoxyribonucleic…

生物物理 · 物理学 2022-01-28 Santosh KC , Ramin Abolfath

In this work, the solvation and electronic structure of the aqueous chloride ion solution was investigated using Density Functional Theory (DFT) based \textit{ab initio} molecular dynamics (AIMD). From an analysis of radial distribution…

Adsorption of monovalent and multivalent cat- and anions on a deoxyribose nucleic acid (DNA) molecule from a salt solution is investigated by computer simulation. The ions are modelled as charged hard spheres, the DNA molecule as a point…

软凝聚态物质 · 物理学 2009-11-10 E. Allahyarov , H. Löwen , G. Gompper

Biomolecules couple to their aqueous environment through a variety of noncovalent interactions. Local structures at the surface of DNA and RNA are frequently determined by hydrogen bonds with water molecules, complemented by non-specific…

化学物理 · 物理学 2019-09-10 Benjamin P. Fingerhut , Thomas Elsaesser

A model system is proposed to investigate the chemical equilibrium and mechanical stability of biological spherical-like nanoshells in contact with an aqueous solution with added dissociated electrolyte of a given concentration. The ionic…

软凝聚态物质 · 物理学 2020-02-06 Thiago Colla , Amin Bakhshandeh , Yan Levin

Solvation of ions is ubiquitous on our planet. Solvated ions have a profound effect on the behavior of ionic solutions, which is crucial in nature and technology. Experimentally, ions have been classified into "structure makers" or…

软凝聚态物质 · 物理学 2021-07-27 Rui Shi , Anthony J. Cooper , Hajime Tanaka

We present a semi-quantitative model of condensation of short nucleic acid (NA) duplexes induced by tri-valent cobalt(III) hexammine (CoHex) ions. The model is based on partitioning of bound counterion distribution around singleNA duplex…

生物大分子 · 定量生物学 2016-05-17 Igor S. Tolokh , Aleksander Drozdetski , Lois Pollack , Nathan A. Baker , Alexey V. Onufriev

We present a multi-scale simulation of early stage of DNA damages by the indirect action of hydroxyl ($^\bullet$OH) free radicals generated by electrons and protons. The computational method comprises of interfacing the Geant4-DNA Monte…

生物物理 · 物理学 2015-06-17 Ramin M. Abolfath , David J. Carlson , Zhe J. Chen , Ravinder Nath

Ions in water are important in biology, from molecules to organs. Classically, ions in water are treated as ideal noninteracting particles in a perfect gas. Excess free energy of ion was zero. Mathematics was not available to deal…

生物大分子 · 定量生物学 2015-06-15 Bob Eisenberg

Due to its polyionic character the DNA double helix is stable and biologically active only in salty aqueous media where its charge is compensated by solvent counterions. Monovalent metal ions are ubiquitous in DNA environment and they are…

生物物理 · 物理学 2007-05-23 Alexey K. Mazur

The effects of ionic ordering in DNA water solutions are studied by conductivity experiments. The conductivity measurements are performed for the solutions of DNA with KCl salt in the temperature range from 28 to 70 C. Salt concentration…

生物大分子 · 定量生物学 2014-01-06 O. O. Liubysh , O. M. Alekseev , S. Yu. Tkachov , S. M. Perepelytsya

The solar chromosphere is weakly ionized and interactions between ionized particles and neutral particles likely have significant consequences for the thermodynamics of the plasma. We investigate the importance of introducing neutral…

太阳与恒星天体物理 · 物理学 2015-06-04 Juan Martinez-Sykora , Bart De Pontieu , Viggo Hansteen

Short-range correlations in electrolyte solutions lead to oscillatory profiles of water polarization and ionic concentration at electrode-electrolyte interfaces. The recently developed density-potential-polarization functional theory…

化学物理 · 物理学 2026-03-23 Mengke Zhang , Jun Huang

Describing analytically the transport properties of electrolytes, such as their conductivity or the self-diffusion of the ions, has been a central challenge of chemical physics for almost a century. In recent years, this question has…

软凝聚态物质 · 物理学 2023-09-21 Olivier Bernard , Marie Jardat , Benjamin Rotenberg , Pierre Illien

Structuring of DNA counterions around the double helix has been studied by the molecular dynamics method. A DNA dodecamer d(CGCGAATTCGCG) in water solution with the alkali metal counterions Na$^{+}$, K$^{+}$, and Cs$^{+}$ has been…

生物大分子 · 定量生物学 2015-03-19 O. O. Liubysh , A. V. Vlasiuk , S. M. Perepelytsya

We study the distribution of colloidal particles confined in drying spherical droplets using both dynamic density functional theory (DDFT) and particle-based simulations. In particular, we focus on the advection-dominated regime typical of…

软凝聚态物质 · 物理学 2025-01-24 Mayukh Kundu , Kritika Kritika , Yashraj M. Wani , Arash Nikoubashman , Michael P. Howard

The structure of aqueous CsCl solutions was investigated by classical molecular dynamics simulations (MD) at three salt concentrations (1.5, 7.5, and 15 mol %). Thirty interatomic potential sets, based on the 12-6 Lennard-Jones model,…

化学物理 · 物理学 2022-06-27 Ildikó Pethes

An argon-xenon (Ar/Xe) plasma is used as a model system for complex plasmas. Based on this system, symmetric low-pressure capacitively coupled radio-frequency discharges are examined utilizing Particle-In-Cell/Monte Carlo Collisions…

等离子体物理 · 物理学 2021-08-11 M. Klich , S. Wilczek , J. F. J. Janssen , R. P. Brinkmann , T. Mussenbrock , J. Trieschmann
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