相关论文: An immersed boundary model of the cochlea with par…

Sound produces surface waves along the cochlea's basilar membrane. To achieve the ear's astonishing frequency resolution and sensitivity to faint sounds, dissipation in the cochlea must be canceled via active processes in hair cells,…

Most sounds of interest consist of complex, time-dependent admixtures of tones of diverse frequencies and variable amplitudes. To detect and process these signals, the ear employs a highly nonlinear, adaptive, real-time spectral analyzer:…

The human cochlea is a remarkable device, able to discern extremely small amplitude sound pressure waves, and discriminate between very close frequencies. Simulation of the cochlea is computationally challenging due to its complex geometry,…

The sensitivity and frequency selectivity of hearing result from tuned amplification by an active process in the mechanoreceptive hair cells. In most vertebrates the active process stems from the active motility of hair bundles. The…

The extraordinary sensitivity of the mammalian inner ear has captivated scientists for decades, largely due to the crucial role played by the outer hair cells (OHCs) and their unique electromotile properties. Typically arranged in three…

High auditory sensitivity, sharp frequency selectivity, and otoacoustic emissions are signatures of active amplification of the cochlea. The human ear can also detect very large amplitude sound without being damaged as long as the exposed…

We describe a numerical method to simulate an elastic shell immersed in a viscous incompressible fluid. The method is developed as an extension of the immersed boundary method using shell equations based on the Kirchhoff-Love and the planar…

This paper discusses the role of 2-D/3-D cochlear fluid hydrodynamics in the generation of the large nonlinear dynamical range of the basilar membrane (BM) and pressure response, in the decoupling between cochlear gain and tuning, and in…

After entering the ear, sound waves propagate as surface waves along the cochlea's basilar membrane. In recent work, we showed numerically that the system supports two types of modes: localized resonant modes, which underpin the modern…

A hearing sensation arises when the elastic basilar membrane inside the cochlea vibrates. The basilar membrane is typically set into motion through airborne sound that displaces the middle ear and induces a pressure difference across the…

The inner ear achieves a wide dynamic range of responsiveness by mechanically amplifying weak sounds. The enormous mechanical gain reported for the mammalian cochlea, which exceeds a factor of 4,000, poses a challenge for theory. Here we…

We perform a stability analysis for a fluid-structure interaction problem in which a spherical elastic shell or membrane is immersed in a 3D viscous, incompressible fluid. The shell is an idealised structure having zero thickness, and has…

Cochlea is an important auditory organ in the inner ear. In most mammals, it is coiled as a spiral. Whether this specific shape influences hearing is still an open problem. By employing a three dimensional fluid model of the cochlea with an…

A nonlinear nonlocal cochlear model of the transmission line type is studied in order to capture the multitone interactions and resulting tonal suppression effects. The model can serve as a module for voice signal processing, it is a one…

The auditory system displays remarkable sensitivity and frequency discrimination, attributes shown to rely on an amplification process that involves a mechanical as well as a biochemical response. Models that display proximity to an…

Cochlear wavenumber and impedance are mechanistic variables that encode information regarding how the cochlea works - specifically wave propagation and Organ of Corti dynamics. These mechanistic variables underlie interesting features of…

A mathematical model describing the coupling between two independent amplification mechanisms in auditory hair cells is proposed and analyzed. Hair cells are cells in the inner ear responsible for translating sound-induced mechanical…

Cochlear implants (CIs) are devices that restore the sense of hearing in people with severe sensorineural hearing loss. An electrode array inserted in the cochlea bypasses the natural transducer mechanism that transforms mechanical sound…

We present a novel immersed boundary method that implements acoustic perturbation theory to model an acoustically levitated droplet. Instead of resolving sound waves numerically, our hybrid method solves acoustic scattering…

In fluid-filled microchannels embedded in solid devices and driven by MHz ultrasound transducers, the thickness of the viscous boundary layer in the fluid near the confining walls is typically 3 to 4 orders of magnitude smaller than the…