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Purpose: To derive a clinically-practical margin formula between clinical target volume (CTV) and planning target volume (PTV) for single-fraction stereotactic radiosurgery (SRS).Methods: In previous publications on the margin between the…

医学物理 · 物理学 2012-07-16 Qinghui Zhang , Maria Chan , Yulin Song , Chandra Burman

Purpose: This study quantifies the variation in dose-volume histogram (DVH) and normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer patients when alternative organ-at-risk (OAR) delineations are used for…

Aim: To examine and quantify set-up errors in patient positioning in head-and-neck radiotherapy and to investigate the impact of the choice of reference isocentre -- on the patient neck or patient skull -- on the magnitude of set-up errors.…

医学物理 · 物理学 2023-02-28 Helena Lenko , Primož Peterlin

Setting a proper margin is crucial for not only delivering the required radiation dose to a target volume, but also reducing the unnecessary radiation to the adjacent organs at risk. This study investigated the independent one-dimensional…

医学物理 · 物理学 2014-03-05 Qinghui Zhang , Maria Chan , Chandra Burman , Yulin Song , Mutian Zhang

Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

医学物理 · 物理学 2024-11-14 R. M. Winter , O. Engelsen , O. J. Bratting , N. Brekke , J. Sæterstøl , O. Sæther , K. R. Redalen

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

Precise patient positioning and thus precise positioning of the planning target volume (PTV) is a prerequisite for effective treatment in percutaneous radiation therapy. Conventional imaging modalities used to ensure exact positioning for…

医学物理 · 物理学 2016-02-12 Manfred Wiencierz , Kathrin Kruppa , Lutz Lüdemann

Three-dimensional segmentation in magnetic resonance images (MRI), which reflects the true shape of the objects, is challenging since high-resolution isotropic MRIs are rare and typical MRIs are anisotropic, with the out-of-plane dimension…

图像与视频处理 · 电气工程与系统科学 2023-03-15 Hanxue Gu , Hongyu He , Roy Colglazier , Jordan Axelrod , Robert French , Maciej A Mazurowski

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

Background: This study aimed to predict lesion-specific outcomes after stereotactic radiotherapy (SRT) in patients with brain metastases from malignant melanoma (MBM), using clinical, dosimetric, and pretherapeutic MRI data. Methods: In…

Stereotactic radiosurgery (SRS), which delivers high doses of irradiation in a single or few shots to small targets, has been a standard of care for brain metastases. While very effective, SRS currently requires manually intensive…

图像与视频处理 · 电气工程与系统科学 2019-08-16 Szu-Yeu Hu , Wei-Hung Weng , Shao-Lun Lu , Yueh-Hung Cheng , Furen Xiao , Feng-Ming Hsu , Jen-Tang Lu

This paper investigates an extremely challenging problem: barely-supervised volumetric medical image segmentation (BSS). A BSS training dataset consists of two parts: 1) a barely-annotated labeled set, where each labeled image contains only…

计算机视觉与模式识别 · 计算机科学 2024-09-05 Zhiqiang Shen , Peng Cao , Junming Su , Jinzhu Yang , Osmar R. Zaiane

Recently, anomaly detection and localization in multimedia data have received significant attention among the machine learning community. In real-world applications such as medical diagnosis and industrial defect detection, anomalies only…

计算机视觉与模式识别 · 计算机科学 2022-05-16 Chaoqin Huang , Qinwei Xu , Yanfeng Wang , Yu Wang , Ya Zhang

High-quality 3D fetal brain MRI reconstruction from motion-corrupted 2D slices is crucial for clinical diagnosis. Reliable slice-to-volume registration (SVR)-based motion correction and super-resolution reconstruction (SRR) methods are…

图像与视频处理 · 电气工程与系统科学 2025-05-27 Jiangjie Wu , Lixuan Chen , Zhenghao Li , Xin Li , Saban Ozturk , Lihui Wang , Rongpin Wang , Hongjiang Wei , Yuyao Zhang

Automatic tissue segmentation of fetal brain images is essential for the quantitative analysis of prenatal neurodevelopment. However, producing voxel-level annotations of fetal brain imaging is time-consuming and expensive. To reduce…

图像与视频处理 · 电气工程与系统科学 2023-10-24 Zihang Xu , Haifan Gong , Xiang Wan , Haofeng Li

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

计算机视觉与模式识别 · 计算机科学 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

Face morphing attacks represent a significant threat to biometric systems as they allow multiple identities to be combined into a single face. While supervised morphing attack detection (MAD) methods have shown promising performance, their…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Diogo J. Paulo , Hugo Proença , João C. Neves

Spatial precision is often measured using the standard deviation (SD) of the eye position signal or the RMS of the sample-to-sample differences (StoS) signal during fixation. As both measures emerge from statistical theory applied to…

神经元与认知 · 定量生物学 2023-03-13 Lee Friedman , Timothy Hanson , Hal S. Stern , Oleg V. Komogortsev

Background: Tumor segmentation in MRI is crucial in radiotherapy (RT) treatment planning for brain tumor patients. Segment anything (SA), a novel promptable foundation model for autosegmentation, has shown high accuracy for multiple…

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