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In this study, two proton beam delivery designs, passive scattering proton therapy (PSPT) and pencil beam scanning (PBS), were quantitatively compared in terms of dosimetric indices. The GATE Monte Carlo code was used to simulate the proton…

医学物理 · 物理学 2022-09-21 A. Asadi , A. Akhavanallaf , S. A. Hosseini , H. Zaidi

We present the design and optimization of a Tomographic Gamma Scanning (TGS) collimator based on Monte Carlo simulations using MCNP5 computer code. In these simulations, an accurate Monte Carlo model of TGS was built and the collimator…

仪器与探测器 · 物理学 2014-09-09 Zhang Jinzhao Tuo Xianguo

The application of metal nanoparticles as sensitization materials is a common strategy that is used to study dose enhancement in radiotherapy. Recent in vitro tests have revealed that magnetic gold nanoparticles can be used in cancer…

医学物理 · 物理学 2021-06-15 Xiaohan Xu , Yaoqin Xie , Jianan Wu , Zhitao Dai , Rui Hu , Luhua Wang

Treating realistically the ambient water is one of the main difficulties in applying Monte Carlo methods to protein folding. The solvent-accessible area method, a popular method for treating water implicitly, is investigated by means of…

软凝聚态物质 · 物理学 2007-05-23 Hsiao-Ping Hsu , Bernd A. Berg , Peter Grassberger

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

Objective. The objective of the presented study was to evaluate the feasibility of a coded-mask (CM) gamma camera for real-time range verification in proton therapy, addressing the need for a precise and efficient method of treatment…

Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…

We investigate thermal rectification in nanoporous silicon using a semi-classical Monte Carlo (MC) simulation method. We consider geometrically asymmetric nanoporous structures, and investigate the combined effects of porosity, inter-pore…

材料科学 · 物理学 2019-11-18 Dhritiman Chakraborty , Joshua Brooke , Nick C S Hulse , Neophytos Neophytou

Purpose: This work advances a Monte Carlo (MC) method to combine ionizing radiation physics with optical physics, in a manner which was implicitly designed for deployment with the most widely accessible parallelization and portability…

医学物理 · 物理学 2020-05-05 Ethan P. M. LaRochelle , Pedro Arce , Brian W. Pogue

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

An open source software package for simulating thermal neutron propagation in geometry is presented. In this system, neutron propagation can be treated by either the particle transport method or the ray-tracing method. Supported by an…

计算物理 · 物理学 2023-12-05 Zi-Yi Pan , Ni Yang , Ming Tang , Peixun Shen , Xiao-Xiao Cai

During the last decades, neutron beam transportation has been a well-known and established subject for designing proper neutron guides. However, sometimes unusual adaptation or adjustments are required out of original projects and after…

仪器与探测器 · 物理学 2022-03-29 Alexandre P. S. Souza , Luiz P. de Oliveira , Frederico A. Genezini

The TOP-IMPLART project consists of the design and implementation of a linear proton accelerator, its control and monitoring systems for the treatment of superficial and semi-deep tumors. The energy of 150 MeV (corresponding to a…

This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customization and precision. As adaptive radiotherapy and other…

医学物理 · 物理学 2024-04-24 Jason Holmes , Hongying Feng , Lian Zhang , Michael Fix , Steve B. Jiang , Wei Liu

Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…

仪器与探测器 · 物理学 2020-07-28 F. Ulrich-Pur , T. Bergauer , A. Burker , S. Hatamikia , A. Hirtl , C. Irmler , S. Kaser , P. Paulitsch , F. Pitters , V. Teufelhart

The Monte Carlo (MC) setups used by ATLAS to model boson$+\mathrm{jets}$ and multi-boson processes at $\sqrt{s}$ = 13 TeV in proton-proton collisions are described. Comparisons between data and several event generators are provided for key…

高能物理 - 实验 · 物理学 2017-09-05 Francesco Giuli

Optical trapping techniques are an efficient way to probe limited quantities of rare isotopes. In order to achieve the highest possible measurement precision, it is critical to optimize the optical trapping efficiency. This work presents…

Background: Dose calculation and optimization algorithms in proton therapy treatment planning often have high computational requirements regarding time and memory. This can hinder the implementation of efficient workflows in clinics and…

医学物理 · 物理学 2023-04-18 D. Pross , S. Wuyckens , S. Deffet , E. Sterpin , J. A. Lee , K. Souris

Targeted Radionuclide Therapy (TRT) is a well-established technique for cancer treatment. In this approach, radionuclides are bound to specific drugs that selectively transport them to the tumor site. Within the ISOLPHARM project, a…

No fast neutron therapy facility has been built with optimized beam quality based on a thorough understanding of the neutron spectrum and its resulting biological effectiveness. A study has been initiated to provide the information…

加速器物理 · 物理学 2012-07-09 T. K. Kroc