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In recent years, numerous research efforts have been dedicated towards developing efficient implantable devices for brain stimulation. However, there are limitations and challenges with the current technologies. Firstly, the stimulation of…

This paper studies magnetic induction for wireless powering and the data uplink of microsensors, in particular for future medical in-body applications. We consider an external massive coil array as power source (1 W) and data sink. For…

信号处理 · 电气工程与系统科学 2024-10-30 Gregor Dumphart , Bertold Ian Bitachon , Armin Wittneben

In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…

信号处理 · 电气工程与系统科学 2022-11-28 Alexander Tarnavsky Eitan , Shirly Someck , Mario Zajac , Eran Socher , Eran Stark

Optogenetics has emerged as an exciting tool for manipulating neural activity, which in turn, can modulate behavior in live organisms. However, detecting the response to the optical stimulation requires electrophysiology with physical…

This article presents a hardware platform including stimulating implants wirelessly powered and controlled by a shared transmitter (TX) for coordinated leadless multisite stimulation. The adopted novel single-TX, multiple-implant structure…

信号处理 · 电气工程与系统科学 2022-01-03 Zhanghao Yu , Joshua C. Chen , Yan He , Fatima T. Alrashdan , Benjamin W. Avants , Amanda Singer , Jacob T. Robinson , Kaiyuan Yang

Objective. Long-term potentiation (LTP) is a fundamental mechanism underlying learning and memory, yet its investigation at the network level in vitro remains challenging, particularly when optogenetic stimulation is used. The objective of…

生物物理 · 物理学 2026-02-13 Matteo Dominici , Ilya Auslender , Clara Zaccaria , Yasaman Heydari , Lorenzo Pavesi

This paper presents the first wireless and programmable neural stimulator leveraging magnetoelectric (ME) effects for power and data transfer. Thanks to low tissue absorption, low misalignment sensitivity and high power transfer efficiency,…

Objective: Optogenetic manipulations of excitable cells enable activating or silencing specific types of neurons. By expressing two types of exogenous proteins, a single neuron can be depolarized using light of one wavelength and…

系统与控制 · 电气工程与系统科学 2022-11-28 Ori Noked , Amir Levi , Shirly Someck , Ortal Amber-Vitos , Eran Stark

Neural stimulation is a powerful technique for modulating physiological functions and for writing information into the nervous system as part of brain-machine interfaces. Current clinically approved neural stimulators require batteries and…

Nerve stimulation via micro-electrode implants is one of the neurostimulation approaches which is used frequently in the medical treatment of some brain disorders, neural prosthetics, brain-machine interfaces and also in the cyborg. In this…

生物物理 · 物理学 2019-04-30 Yousef Jamali , Mohammad Jamali , Mehdi Golshani

The design and benchtop operation of a wireless miniature epiretinal stimulator implant is reported. The implant is optically powered and controlled using safe illumination at near-infrared wavelengths. An application-specific integrated…

The brain stimulation and its widespread use is one of the most important subjects in studies of neurophysiology. In brain electrical stimulation methods, following the surgery and electrode implantation, electrodes send electrical impulses…

神经元与认知 · 定量生物学 2019-01-11 Amirmasoud Ahmadi , Sepideh Farakhor Seghinsara , Mohammad Reza Daliri , Vahid Shalchyan

Transcranial photobiomodulation is an optical method for non-invasive brain stimulation. The method projects red and near-infrared light through the scalp within 600-1100 nm and low energy within the 1-20 J/cm2 range. Recent studies have…

数值分析 · 数学 2022-12-12 Faezeh Ibrahimi , Mehdi Delrobaei

Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

In brain activity mapping experiments using optogenetics, patterned illumination is crucial for deterministic and localized stimulation of neurons. However, due to optical scattering in brain tissue, light-emitting implantable devices are…

Electrical brain stimulation is currently being investigated as a therapy for neurological disease. However, opportunities to optimize such therapies are challenged by the fact that the beneficial impact of focal stimulation on both…

Neural probes are in vivo invasive devices that combine electrophysiology and optogenetics to gain insight into how the brain operates, down to the single neuron and its network activity. Their integration of stimulation sites and sensors…

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

系统与控制 · 电气工程与系统科学 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

The functioning of the human brain, nervous system and heart is based on the conduction of electrical signals. These electrical signals also create magnetic fields which extend outside the human body. Highly sensitive magnetometers, such as…

医学物理 · 物理学 2022-12-07 Kasper Jensen , Bo Hjorth Bentzen , Eugene S. Polzik

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

其他定量生物学 · 定量生物学 2016-03-08 Erich W. Schmid
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