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Emerging topics in biomedical research are continuously expanding, providing a wealth of information about genes and their function. This rapid proliferation of knowledge presents unprecedented opportunities for scientific discovery and…

基因组学 · 定量生物学 2024-12-25 Zhijian Chen , Chuan Hu , Min Wu , Qingqing Long , Xuezhi Wang , Yuanchun Zhou , Meng Xiao

This paper introduces kDGLM, an R package designed for Bayesian analysis of Generalized Dynamic Linear Models (GDLM), with a primary focus on both uni- and multivariate exponential families. Emphasizing sequential inference for time series…

统计方法学 · 统计学 2024-03-21 Silvaneo V. dos Santos , Mariane Branco Alves , Helio S. Migon

Bayesian methods for learning Gaussian graphical models offer a principled framework for quantifying model uncertainty and incorporating prior knowledge. However, their scalability is constrained by the computational cost of jointly…

统计方法学 · 统计学 2025-08-28 Reza Mohammadi , Marit Schoonhoven , Lucas Vogels , S. Ilker Birbil

The sparsity-restricted maximum likelihood estimator (SMLE) has received considerable attention for feature screening in ultrahigh-dimensional regression. SMLE is a computationally convenient method that naturally incorporates the joint…

其他统计学 · 统计学 2022-01-11 Qianxiang Zang , Chen Xu , Kelly Burkett

Due to their flexibility and superior performance, machine learning models frequently complement and outperform traditional statistical survival models. However, their widespread adoption is hindered by a lack of user-friendly tools to…

Presence-only data are referred to situations in which, given a censoring mechanism, a binary response can be observed only with respect to on outcome, usually called \textit{presence}. In this work we present a Bayesian approach to the…

统计计算 · 统计学 2013-05-07 Fabio Divino , Natalia Golini , Giovanna Jona Lasinio , Antti Penttinen

Ranking data represent a peculiar form of multivariate ordinal data taking values in the set of permutations. Despite the numerous methodological contributions to increase the flexibility of ranked data modeling, the application of more…

统计计算 · 统计学 2018-03-13 Cristina Mollica , Luca Tardella

We present BayeSum (for ``Bayesian summarization''), a model for sentence extraction in query-focused summarization. BayeSum leverages the common case in which multiple documents are relevant to a single query. Using these documents as…

计算与语言 · 计算机科学 2009-07-13 Hal Daumé

Partially observed Markov process (POMP) models, also known as hidden Markov models or state space models, are ubiquitous tools for time series analysis. The R package pomp provides a very flexible framework for Monte Carlo statistical…

统计方法学 · 统计学 2021-05-27 Aaron A. King , Dao Nguyen , Edward L. Ionides

Bayesian structural equation modelling (BSEM) offers many advantages such as principled uncertainty quantification, small-sample regularisation, and flexible model specification. However, the Markov chain Monte Carlo (MCMC) methods on which…

统计计算 · 统计学 2026-05-20 Haziq Jamil , Håvard Rue

Multilevel network meta-regression (ML-NMR) enables population-adjusted indirect treatment comparisons by combining individual patient data (IPD) with aggregate data. When individual-level covariates are unavailable, ML-NMR marginalizes…

统计方法学 · 统计学 2026-03-12 Harlan Campbell , Charles C. Margossian , Jeroen P. Jansen , Paul Gustafson

The joint modeling of longitudinal and time-to-event outcomes has become a popular tool in follow-up studies. However, fitting Bayesian joint models to large datasets, such as patient registries, can require extended computing times. To…

Regression models are used for inference and prediction in a wide range of applications providing a powerful scientific tool for researchers and analysts from different fields. In many research fields the amount of available data as well as…

统计方法学 · 统计学 2018-06-08 Aliaksandr Hubin , Geir Storvik , Florian Frommlet

Directed Acyclic Graphs (DAGs) provide a powerful framework to model causal relationships among variables in multivariate settings; in addition, through the do-calculus theory, they allow for the identification and estimation of causal…

机器学习 · 统计学 2022-01-31 Federico Castelletti , Alessandro Mascaro

The analysis of longitudinal data gives the chance to observe how unit behaviors change over time, but it also poses a series of issues. These have been the focus of an extensive literature in the context of linear and generalized linear…

统计计算 · 统计学 2025-10-20 Marco Alfó , Maria Francesca Marino , Maria Giovanna Ranalli , Nicola Salvati

Implementing Bayesian variable selection for linear Gaussian regression models for analysing high dimensional data sets is of current interest in many fields. In order to make such analysis operational, we propose a new sampling algorithm…

统计计算 · 统计学 2010-02-16 Leonardo Bottolo , Sylvia Richardson

It is shown how to set up, conduct, and analyze large simulation studies with the new R package simsalapar = simulations simplified and launched parallel. A simulation study typically starts with determining a collection of input variables…

统计计算 · 统计学 2013-09-18 Marius Hofert , Martin Mächler

Bayesian network (BN) modelling is extensively used in systems epidemiology. Usually it consists in selecting and reporting the best-fitting structure conditional to the data. A major practical concern is avoiding overfitting, on account of…

统计计算 · 统计学 2019-02-19 Gilles Kratzer , Reinhard Furrer

This article describes an R package bqror that estimates Bayesian quantile regression for ordinal models introduced in Rahman (2016). The paper classifies ordinal models into two types and offers computationally efficient, yet simple,…

计量经济学 · 经济学 2023-05-30 Prajual Maheshwari , Mohammad Arshad Rahman

With the advent of high-throughput sequencing (HTS) in molecular biology and medicine, the need for scalable statistical solutions for modeling complex biological systems has become of critical importance. The increasing number of platforms…

分子网络 · 定量生物学 2022-10-19 Fernando Palluzzi , Mario Grassi