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Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

统计方法学 · 统计学 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

应用统计 · 统计学 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

神经元与认知 · 定量生物学 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

神经元与认知 · 定量生物学 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Although developed functional magnetic resonance imaging (fMRI) registration algorithms based on deep learning have achieved a certain degree of alignment of functional area, they underutilized fine structural information. In this paper, we…

图像与视频处理 · 电气工程与系统科学 2024-09-27 Baolong Li , Yuhu Shi , Lei Wang , Weiming Zeng , Changming Zhu

Diffusion-weighted magnetic resonance imaging (dMRI) allows non-invasive investigation of whole-brain connectivity, which can potentially help to reveal the brain's global network architecture and abnormalities involved in neurological and…

Estimation of Markov Random Field and covariance models from high-dimensional data represents a canonical problem that has received a lot of attention in the literature. A key assumption, widely employed, is that of {\em sparsity} of the…

最优化与控制 · 数学 2018-05-16 Davoud Ataee Tarzanagh , George Michailidis

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

机器学习 · 计算机科学 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

神经元与认知 · 定量生物学 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Current connectivity diagrams of human brain image data are either overly complex or overly simplistic. In this work we introduce simple yet accurate interactive visual representations of multiple brain image structures and the connectivity…

图形学 · 计算机科学 2016-09-02 Saad Nadeem , Arie Kaufman

Understanding how the brain encodes external stimuli and how these stimuli can be decoded from the measured brain activities are long-standing and challenging questions in neuroscience. In this paper, we focus on reconstructing the complex…

神经元与认知 · 定量生物学 2022-10-05 Sikun Lin , Thomas Sprague , Ambuj K Singh

Functional connectomes derived from functional magnetic resonance imaging have long been used to understand the functional organization of the brain. Nevertheless, a connectome is intrinsically linked to the atlas used to create it. In…

神经元与认知 · 定量生物学 2021-07-06 Javid Dadashkarimi , Amin Karbasi , Dustin Scheinost

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

图像与视频处理 · 电气工程与系统科学 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

Autism Spectrum Disorder(ASD) is a set of neurodevelopmental conditions that affect patients' social abilities. In recent years, many studies have employed deep learning to diagnose this brain dysfunction through functional MRI (fMRI).…

图像与视频处理 · 电气工程与系统科学 2021-10-26 Li Pan , Jundong Liu , Mingqin Shi , Chi Wah Wong , Kei Hang Katie Chan

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

物理与社会 · 物理学 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

神经元与认知 · 定量生物学 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure--function issue, treating a system of Jansen--Rit neural-mass…

神经元与认知 · 定量生物学 2020-07-10 Michael Forrester , Stephen Coombes , Jonathan J. Crofts , Stamatios N. Sotiropoulos , Reuben D. O'Dea

Integrating the brain structural and functional connectivity features is of great significance in both exploring brain science and analyzing cognitive impairment clinically. However, it remains a challenge to effectively fuse structural and…

神经元与认知 · 定量生物学 2023-05-25 Qiankun Zuo , Baiying Lei , Ning Zhong , Yi Pan , Shuqiang Wang

Understanding how the brain encodes visual information is a central challenge in neuroscience and machine learning. A promising approach is to reconstruct visual stimuli, essentially images, from functional Magnetic Resonance Imaging (fMRI)…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Zheng Huang , Enpei Zhang , Weikang Qiu , Yinghao Cai , Carl Yang , Elynn Chen , Xiang Zhang , Rex Ying , Dawei Zhou , Yujun Yan