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In recent years, functional magnetic resonance imaging has emerged as a powerful tool for investigating the human brain's functional connectivity networks. Related studies demonstrate that functional connectivity networks in the human brain…

人工智能 · 计算机科学 2023-09-18 Xiangzhu Meng , Wei Wei , Qiang Liu , Shu Wu , Liang Wang

Dynamic Causal Modelling (DCM) is the predominant method for inferring effective connectivity from neuroimaging data. In the 15 years since its introduction, the neural models and statistical routines in DCM have developed in parallel,…

Graph generation is a crucial task in many fields, including network science and bioinformatics, as it enables the creation of synthetic graphs that mimic the properties of real-world networks for various applications. Graph Generative…

机器学习 · 计算机科学 2026-01-21 Salvatore Romano , Marco Grassia , Giuseppe Mangioni

We investigate the effect of cadmium (a toxic environmental pollutant) on the correlation structure of a number of urinary metabolites using Gaussian graphical models (GGMs). The inferred metabolic associations can provide important…

统计方法学 · 统计学 2019-04-23 Linda S. L. Tan , Ajay Jasra , Maria De Iorio , Timothy M. D. Ebbels

Gaussian graphical models (GGM) have been widely used in many high-dimensional applications ranging from biological and financial data to recommender systems. Sparsity in GGM plays a central role both statistically and computationally.…

机器学习 · 统计学 2014-06-12 Zhaoshi Meng , Brian Eriksson , Alfred O. Hero

Gaussian graphical models (GGMs) are well-established tools for probabilistic exploration of dependence structures using precision matrices. We develop a Bayesian method to incorporate covariate information in this GGMs setup in a nonlinear…

Using predictive models to identify patterns that can act as biomarkers for different neuropathoglogical conditions is becoming highly prevalent. In this paper, we consider the problem of Autism Spectrum Disorder (ASD) classification where…

机器学习 · 统计学 2018-10-31 Rushil Anirudh , Jayaraman J. Thiagarajan

Magnetic Resonance Imaging (MRI) of the brain has been used to investigate a wide range of neurological disorders, but data acquisition can be expensive, time-consuming, and inconvenient. Multi-site studies present a valuable opportunity to…

计算机视觉与模式识别 · 计算机科学 2018-04-13 Harrison Nguyen , Richard W. Morris , Anthony W. Harris , Mayuresh S. Korgoankar , Fabio Ramos

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

应用统计 · 统计学 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

应用统计 · 统计学 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

计算几何 · 计算机科学 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

Network topology inference is a prominent problem in Network Science. Most graph signal processing (GSP) efforts to date assume that the underlying network is known, and then analyze how the graph's algebraic and spectral characteristics…

信号处理 · 电气工程与系统科学 2019-05-22 Gonzalo Mateos , Santiago Segarra , Antonio G. Marques , Alejandro Ribeiro

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

应用统计 · 统计学 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

Neuroscience has recently made much progress, expanding the complexity of both neural-activity measurements and brain-computational models. However, we lack robust methods for connecting theory and experiment by evaluating our new big…

定量方法 · 定量生物学 2023-07-06 Heiko H. Schütt , Alexander D. Kipnis , Jörn Diedrichsen , Nikolaus Kriegeskorte

The inference of networks of dependencies by Gaussian Graphical models on high-throughput data is an open issue in modern molecular biology. In this paper we provide a comparative study of three methods to obtain small sample and high…

分子网络 · 定量生物学 2022-03-02 P. F. Stifanelli , T. M. Creanza , R. Anglani , V. C. Liuzzi , S. Mukherjee , N. Ancona

fMRI is a non-invasive technique for investigating brain activity, offering high-resolution insights into neural processes. Understanding and decoding cognitive brain states from fMRI depends on how functional interactions are represented.…

神经元与认知 · 定量生物学 2026-02-23 Daniil Vlasenko , Vadim Ushakov , Alexey Zaikin , Denis Zakharov

Inferring synaptic connectivity from neural population activity is a fundamental challenge in computational neuroscience, complicated by partial observability and mismatches between inference models and true circuit dynamics. In this study,…

神经元与认知 · 定量生物学 2025-10-28 Kijung Yoon

In contrast to conventional, univariate analysis, various types of multivariate analysis have been applied to functional magnetic resonance imaging (fMRI) data. In this paper, we compare two contemporary approaches for multivariate…

应用统计 · 统计学 2018-02-08 Ethan C. Jackson , James Alexander Hughes , Mark Daley

Conditional correlation networks, within Gaussian Graphical Models (GGM), are widely used to describe the direct interactions between the components of a random vector. In the case of an unlabelled Heterogeneous population, Expectation…

统计理论 · 数学 2022-03-09 Thomas Lartigue , Stanley Durrleman , Stéphanie Allassonnière

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

应用统计 · 统计学 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani