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We propose a general Bayesian nonparametric (BNP) approach to causal inference in the point treatment setting. The joint distribution of the observed data (outcome, treatment, and confounders) is modeled using an enriched Dirichlet process.…

统计方法学 · 统计学 2017-03-01 Jason Roy , Kirsten J Lum , Michael J. Daniels , Bret Zeldow , Jordan Dworkin , Vincent Lo Re

We consider the problem of inferring the values of an arbitrary set of variables (e.g., risk of diseases) given other observed variables (e.g., symptoms and diagnosed diseases) and high-dimensional signals (e.g., MRI images or EEG). This is…

机器学习 · 统计学 2019-02-07 Hao Wang , Chengzhi Mao , Hao He , Mingmin Zhao , Tommi S. Jaakkola , Dina Katabi

Estimating dependence relationships between variables is a crucial issue in many applied domains, such as medicine, social sciences and psychology. When several variables are entertained, these can be organized into a network which encodes…

统计方法学 · 统计学 2025-01-01 Federico Castelletti

This paper develops a Bayesian graphical model for fusing disparate types of count data. The motivating application is the study of bacterial communities from diverse high dimensional features, in this case transcripts, collected from…

Graphical models provide a framework for exploration of multivariate dependence patterns. The connection between graph and statistical model is made by identifying the vertices of the graph with the observed variables and translating the…

统计理论 · 数学 2008-02-08 Mathias Drton , Michael D. Perlman

Distributed Gaussian processes (DGPs) are prominent local approximation methods to scale Gaussian processes (GPs) to large datasets. Instead of a global estimation, they train local experts by dividing the training set into subsets, thus…

机器学习 · 计算机科学 2021-11-10 Hamed Jalali , Gjergji Kasneci

Doubly intractable distributions arise in many settings, for example in Markov models for point processes and exponential random graph models for networks. Bayesian inference for these models is challenging because they involve intractable…

统计计算 · 统计学 2019-04-03 Jaewoo Park , Murali Haran

We propose a network structure discovery model for continuous observations that generalizes linear causal models by incorporating a Gaussian process (GP) prior on a network-independent component, and random sparsity and weight matrices as…

机器学习 · 计算机科学 2017-03-01 Amir Dezfouli , Edwin V. Bonilla , Richard Nock

Gaussian process emulators of computationally expensive computer codes provide fast statistical approximations to model physical processes. The training of these surrogates depends on the set of design points chosen to run the simulator.…

统计计算 · 统计学 2016-08-16 A. Garbuno-Inigo , F. A. DiazDelaO , K. M. Zuev

Background In a study performed on multiplex Multiple Sclerosis (MS) Sardinian families to identify disease causing plasma proteins, application of Mendelian Randomization (MR) methods encounters difficulties due to relatedness of…

Detecting associations between microbial compositions and sample characteristics is one of the most important tasks in microbiome studies. Most of the existing methods apply univariate models to single microbial species separately, with…

统计方法学 · 统计学 2021-03-18 Boyu Ren , Sergio Bacallado , Stefano Favaro , Tommi Vatanen , Curtis Huttenhower , Lorenzo Trippa

Recent evidence suggests that analyzing the presence/absence of taxonomic features can offer a compelling alternative to differential abundance analysis in microbiome studies. However, standard approaches to differential prevalence analysis…

统计方法学 · 统计学 2026-05-26 Juho Pelto , Kari Auranen , Janne V. Kujala , Leo Lahti

This study investigates the generation of high-quality synthetic categorical data, such as survey data, using causal graph models. Generating synthetic data aims not only to create a variety of data for training the models but also to…

人工智能 · 计算机科学 2025-04-17 Olha Shaposhnyk , Noor Abid , Mouri Zakir , Svetlana Yanushkevich

The early detection of Alzheimer's disease (AD) requires an understanding of the relationships between a wide range of features. Conditional independencies and partial correlations are suitable measures for these relationships, because they…

应用统计 · 统计学 2025-01-22 Lucas Vogels , Reza Mohammadi , Marit Schoonhoven , S. Ilker Birbil , Martin Dyrba

The two-phase sampling design is a cost-efficient way of collecting expensive covariate information on a judiciously selected subsample. It is natural to apply such a strategy for collecting genetic data in a subsample enriched for exposure…

应用统计 · 统计学 2013-05-27 Jaeil Ahn , Bhramar Mukherjee , Stephen B. Gruber , Malay Ghosh

Bayesian computation for filtering and forecasting analysis is developed for a broad class of dynamic models. The ability to scale-up such analyses in non-Gaussian, nonlinear multivariate time series models is advanced through the…

统计方法学 · 统计学 2022-06-07 Isaac Lavine , Andrew Cron , Mike West

In genome-wide prediction, independence of marker allele substitution effects is typically assumed; however, since early stages of this technology it has been known that nature points to correlated effects. In statistics, graphical models…

定量方法 · 定量生物学 2017-09-21 Carlos Alberto Martínez , Kshitij Khare , Syed Rahman , Mauricio A. Elzo

Estimation of brain functional connectivity from EEG data is of great importance both for medical research and diagnosis. It involves quantifying the conditional dependencies among the activity of different brain areas from the time-varying…

统计方法学 · 统计学 2026-01-06 Alessia Mapelli , Laura Carini , Francesca Ieva , Sara Sommariva

We develop a Bayesian graphical modeling framework for functional data for correlated multivariate random variables observed over a continuous domain. Our method leads to graphical Markov models for functional data which allows the graphs…

统计方法学 · 统计学 2021-08-12 Lin Zhang , Veera Baladandayuthapani , Quinton Neville , Karina Quevedo , Jeffrey S. Morris

The problem of joint estimation of multiple graphical models from high dimensional data has been studied in the statistics and machine learning literature, due to its importance in diverse fields including molecular biology, neuroscience…

统计方法学 · 统计学 2019-07-04 Peyman Jalali , Kshitij Khare , George Michailidis