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We investigate three aspects of the importance of nodes with respect to Susceptible-Infectious-Removed (SIR) disease dynamics: influence maximization (the expected outbreak size given a set of seed nodes), the effect of vaccination (how…

种群与进化 · 定量生物学 2017-12-13 Petter Holme

Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…

机器学习 · 计算机科学 2023-09-07 Bliss Singhal , Fnu Pooja

One of the most central questions in network science is: which nodes are most important? Often this question is answered using structural properties such as high connectedness or centrality in the network. However, static structural…

物理与社会 · 物理学 2021-07-02 Casper van Elteren , Rick Quax , Peter Sloot

Neonates are highly susceptible to seizures, often leading to short or long-term neurological impairments. However, clinical manifestations of neonatal seizures are subtle and often lead to misdiagnoses. This increases the risk of…

Accurate prediction of epileptic seizures has remained elusive, despite the many advances in machine learning and time-series classification. In this work, we develop a convolutional network module that exploits Electroencephalogram (EEG)…

图像与视频处理 · 电气工程与系统科学 2020-07-24 Ramy Hussein , Soojin Lee , Rabab Ward , Martin J. McKeown

The identification of abnormal electrographic activity is important in a wide range of neurological disorders, including epilepsy for localising epileptogenic tissue. However, this identification may be challenging during non-seizure…

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

Coherence analysis plays a vital role in the study of functional brain connectivity. However, coherence captures only linear spectral associations, and thus can produce misleading findings when ignoring variations of connectivity in the…

Background Seizure severity can change from one seizure to the next within individual people with epilepsy. It is unclear if and how seizure severity is modulated over longer timescales. Characterising seizure severity variability over time…

Identifying preictal states -- periods during which seizures are more likely to occur -- remains a central challenge in clinical computational neuroscience. In this study, we introduce a novel framework that embeds functional brain…

神经元与认知 · 定量生物学 2025-05-21 Steven Rico-Aparicio , Martin Guillemaud , Alice Longhena , Vincent Navarro , Louis Cousyn , Mario Chavez

The behavior of the network and its stability are governed by both dynamics of individual nodes as well as their topological interconnections. Attention mechanism as an integral part of neural network models was initially designed for…

机器学习 · 计算机科学 2022-12-20 Nooshin Bahador , Milad Lankarany

We study the role of scale-free structure and noise in collective dynamics of neuronal networks. For this purpose, we simulate and study analytically a cortical circuit model with stochastic neurons. We compare collective neuronal activity…

无序系统与神经网络 · 物理学 2013-03-27 D. Holstein , A. V. Goltsev , J. F. F. Mendes

The neonatal period is the most vulnerable time for the development of seizures. Seizures in the immature brain lead to detrimental consequences, therefore require early diagnosis. The gold-standard for neonatal seizure detection currently…

Inferring strength and direction of interactions from electroencephalographic (EEG) recordings is of crucial importance to improve our understanding of dynamical interdependencies underlying various physiologic and pathophysiologic…

神经元与认知 · 定量生物学 2016-10-07 Klaus Lehnertz , Henning Dickten

Centrality is an important notion in network analysis and is used to measure the degree to which network structure contributes to the importance of a node in a network. While many different centrality measures exist, most of them apply to…

计算机与社会 · 计算机科学 2010-06-04 Kristina Lerman , Rumi Ghosh , Jeon Hyung Kang

To define the neural networks responsible of the epileptic seizure, we had to study the electrophysiological signal in a proper way. The early recognition of the seizure build up could also be defined through the time space mapping of the…

信号处理 · 电气工程与系统科学 2019-11-19 Ridha Jarray , Nawel Jmail , Abir Hadriche , Tarek Frikha , Chokri Ben Amar

Objective: The aim of this study is to develop an efficient and reliable epileptic seizure prediction system using intracranial EEG (iEEG) data, especially for people with drug-resistant epilepsy. The prediction procedure should yield…

神经与进化计算 · 计算机科学 2019-04-09 Ramy Hussein , Mohamed Osama Ahmed , Rabab Ward , Z. Jane Wang , Levin Kuhlmann , Yi Guo

Electroencephalogram (EEG) signals are effective tools towards seizure analysis where one of the most important challenges is accurate detection of seizure events and brain regions in which seizure happens or initiates. However, all…

机器学习 · 计算机科学 2023-01-18 Thi Kieu Khanh Ho , Narges Armanfard

Epilepsy is the most common neurological disorder and an accurate forecast of seizures would help to overcome the patient's uncertainty and helplessness. In this contribution, we present and discuss a novel methodology for the…

Introduction: Approximately 23 million or 30% of epilepsy patients worldwide suffer from drug-resistant epilepsy (DRE). The unpredictability of seizure occurrences, which causes safety issues as well as social concerns, restrict the…

机器学习 · 计算机科学 2024-10-10 Shriya Jaddu , Sidh Jaddu , Camilo Gutierrez , Quincy K. Tran