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In comparative and developmental neuroanatomy one encounters questions regarding the deformation of neural tissue under stress. The motivation of this note is an observation (Barbas {\it et al}) that at cortical folds or gyri, the layers of…

组织与器官 · 定量生物学 2007-05-23 Partha P. Mitra

When it is polarised, a cell develops an asymmetric distribution of specific molecular markers, cytoskeleton and cell membrane shape. Polarisation can occur spontaneously or be triggered by external signals, like gradients of signalling…

偏微分方程分析 · 数学 2013-01-18 Vincent Calvez , Nicolas Meunier , Nicolas Muller , Raphael Voituriez

Recent work on modeling influence propagation focus on progressive models, i.e., once a node is influenced (active) the node stays in that state and cannot become inactive. However, this assumption is unrealistic in many settings where…

社会与信息网络 · 计算机科学 2014-08-28 Vincent Yun Lou , Smriti Bhagat , Laks V. S. Lakshmanan , Sharan Vaswani

Propagation of ultrashort light pulses in disordered multilayers is studied by using numerical simulations in time domain. We consider cases of instantaneous and noninstantaneous Kerr nonlinearities of the structure materials. The…

光学 · 物理学 2014-05-13 Denis Novitsky

Growth and folding in one-layered model tissue sheets are studied in a stochastic, lattice-free single cell model which considers the discrete cellular structure of the tissue, and a coarse grained analytical approach. The polarity of the…

统计力学 · 物理学 2007-05-23 Dirk Drasdo

We reveal that the mechanical pulsation of locally synchronised particles is a generic route to propagate deformation waves. We consider a model of dense repulsive particles whose activity drives periodic change in size of each individual.…

软凝聚态物质 · 物理学 2023-12-12 Yiwei Zhang , Étienne Fodor

Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide, yet there is no disease-modifying therapy up to this date. The biological complexity underlying PD hampers the investigation of the principal…

动力系统 · 数学 2022-12-22 Elena Righetti , Alice Antonello , Luca Marchetti , Enrico Domenici , Federico Reali

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

神经元与认知 · 定量生物学 2024-11-06 Alec MacIver , Hina Shaheen

Traveling waves of neural activity emerge in cortical networks both spontaneously and in response to stimuli. The spatiotemporal structure of waves can indicate the information they encode and the physiological processes that sustain them.…

神经元与认知 · 定量生物学 2023-12-12 Sage Shaw , Zachary P Kilpatrick

Deep brain stimulation (DBS) can alleviate the movement disorders like Parkinson's disease (PD). Indeed, it is known that aberrant beta (13-30Hz)oscillations and the loss of dopaminergic neurons in the basal ganglia-thalamus (BGTH) and…

神经元与认知 · 定量生物学 2021-12-07 Hina Shaheen , Roderick Melnik

We study the propagation of waves in a set of absorbing subwavelength scatterers positioned on a stealth hyperuniform point pattern. We show that spatial correlations in the disorder substantially enhance absorption compared to a fully…

光学 · 物理学 2019-03-27 Florian Bigourdan , Romain Pierrat , Rémi Carminati

The structure of the axon-dendrite connections of neurons of the brain creates a rich spatial structure in which provided various combinations of signals surrounding neurons. Structure of dendritic trees and shape of dendritic spines allow…

人工智能 · 计算机科学 2014-07-25 Alexey Redozubov

Of particular interest for radio and hard X-ray diagnostics of accelerated electrons during solar flares is the understanding of the basic non-linear mechanisms regulating the relaxation of electron beams propagating in turbulent plasmas.…

空间物理 · 物理学 2015-03-06 Nicolas H. Bian , Eduard P. Kontar , Heather Ratcliffe

Competitive neural networks are often used to model the dynamics of perceptual bistability. Switching between percepts can occur through fluctuations and/or a slow adaptive process. Here, we analyze switching statistics in competitive…

神经元与认知 · 定量生物学 2012-12-05 Zachary P Kilpatrick

We report on the spreading of triboelectrically charged glass particles on an oppositely charged surface of a plastic cylindrical container in the presence of a constant mechanical agitation. The particles spread via sticking, as a…

软凝聚态物质 · 物理学 2014-06-11 Deepak Kumar , A. Sane , Smita Gohil , P. R. Bandaru , S. Bhattacharya , Shankar Ghosh

The problem of a random walk in a disordered media is mapped into a model of a random walk with memory. The latter model, as opposed to the former one, does not make reference to a particular realization of the disorder. The equivalence of…

凝聚态物理 · 物理学 2009-10-28 Michele Vendruscolo , Matteo Marsili

Collective cell migration is a key driver of embryonic development, wound healing, and some types of cancer invasion. Here we provide a physical perspective of the mechanisms underlying collective cell migration. We begin with a catalogue…

生物物理 · 物理学 2019-10-08 Ricard Alert , Xavier Trepat

The aim of this paper is to introduce, analyse and test in practice a new mathematical model describing the interplay between biological tissue atrophy driven by pathogen diffusion, with applications to neurodegenerative disorders. This…

数值分析 · 数学 2025-06-23 Valentina Pederzoli , Mattia Corti , Davide Riccobelli , Paola F. Antonietti

The use of network theory to model disease propagation on populations introduces important elements of reality to the classical epidemiological models. The use of random geometric graphs (RGG) is one of such network models that allows for…

物理与社会 · 物理学 2016-12-21 Ernesto Estrada , Sandro Meloni , Matthew Sheerin , Yamir Moreno

This paper presents a simple model for such processes as chaos spreading or turbulence spillover into stable regions. In this simple model the essential transport occurs via inelastic resonant interactions of waves on a lattice. The process…

混沌动力学 · 物理学 2025-05-28 Alexander V. Milovanov , Alexander Iomin , Jens Juul Rasmussen