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Macromolecular complexation leading to coupling of two or more cellular membranes is a crucial step in a number of biological functions of the cell. While other mechanisms may also play a role, adhesion always involves the fluctuations of…

软凝聚态物质 · 物理学 2015-09-02 Timo Bihr , Udo Seifert , Ana-Suncana Smith

Particles with directional interactions are promising building blocks for new functional materials and may serve as models for biological structures. Mutually attractive nanoparticles that are deformable due to flexible surface groups, for…

软凝聚态物质 · 物理学 2016-07-19 Chris H. J. Evers , Jurriaan A. Luiken , Peter G. Bolhuis , Willem K. Kegel

In this study, we present a comprehensive exploration of formation of different phases in lipid molecules using a coarse-grained implicit solvent model, where each lipid molecule is represented as a rigid, three-bead rod-like structure. Our…

软凝聚态物质 · 物理学 2023-12-13 Biplab Bawali , Alokmay Datta , Jayashree Saha

We present a numerical simulation of a granular material using hydrodynamic equations. We show that, in the absence of external forces, such a system phase-separates into high density and low density regions. We show that this separation is…

软凝聚态物质 · 物理学 2009-11-07 Scott A. Hill , Gene F. Mazenko

We establish a complete picture of condensation in the inclusion process in the thermodynamic limit with vanishing diffusion, covering all scaling regimes of the diffusion parameter and including large deviation results for the maximum…

The primary building block of the body is collagen, which is found in the extracellular matrix and in many stress-bearing tissues such as tendon and cartilage. It provides elasticity and support to cells and tissues while influencing…

生物大分子 · 定量生物学 2019-07-29 Michael W. H. Kirkness , Kathrin Lehmann , Nancy R. Forde

Multifarious assembly models consider multiple structures assembled from a shared set of components, reflecting the efficient usage of components in biological self-assembly. These models are subject to a high-dimensional parameter space,…

软凝聚态物质 · 物理学 2025-09-30 Jakob Metson , Saeed Osat , Ramin Golestanian

We describe a simple coarse-grained model which is suited to study lipid layers and their phase transitions. Lipids are modeled by short semiflexible chains of beads with a solvophilic head and a solvophobic tail component. They are forced…

生物物理 · 物理学 2007-08-06 F. Schmid , D. Duchs , O. Lenz , B. West

Polymer-grafted nanoparticles are versatile building blocks that self-assemble into a rich diversity of mesostructures. Coarse-grained molecular simulations have commonly accompanied experiments by resolving structure formation pathways and…

软凝聚态物质 · 物理学 2025-09-30 Federico Tomazic , Aswathy Muttathukattil , Afshin Nabiyan , Felix Schacher , Michael Engel

Self-assembly is a process which is ubiquitous in natural, especially biological systems. It occurs when groups of relatively simple components spontaneously combine to form more complex structures. While such systems have inspired a large…

计算几何 · 计算机科学 2018-07-19 Jerome Durand-Lose , Jacob Hendricks , Matthew J. Patitz , Ian Perkins , Michael Sharp

The control over the self-assembly of complex structures is a long-standing challenge of material science, especially at the colloidal scale, as the desired assembly pathway is often kinetically derailed by the formation of amorphous…

软凝聚态物质 · 物理学 2023-05-03 Diogo E. P. Pinto , Petr Sulc , Francesco Sciortino , John Russo

We use the Dynamic Density-Functional Formalism and the Fundamental Measure Theory as applied to a fluid of parallel hard squares to study the dynamics of heterogeneous growth of non-uniform phases with columnar and crystalline symmetries.…

软凝聚态物质 · 物理学 2022-06-07 Miguel Gonzalez-Pinto , Yuri Martinez-Raton , Enrique Velasco

Magnetic nanoparticles in a colloidal solution self-assemble in various aligned structures, which has a profound influence on the flow behavior. However, the precise role of the microstructure in the development of the rheological response…

软凝聚态物质 · 物理学 2017-04-25 Dmitry Zablotsky , Elmars Blums , Hans J. Herrmann

During the formation of a thrombus, the architecture of the growing platelet aggregate is heterogeneous, with areas of dense and loosely packed platelets. The surface of activated platelets facilitate biochemical coagulation reactions that…

生物大分子 · 定量生物学 2026-04-10 Janneke M. H. Cruts , Frank J. H. Gijsen , Aaron L. Fogelson , Anna C. Nelson

The assembly of filamentous bundles with controlled diameters is common in biological systems and desirable for the development of nanomaterials. We discuss dynamical simulations and free energy calculations on patchy spheres with chiral…

软凝聚态物质 · 物理学 2015-05-18 Yasheng Yang , Robert B. Meyer , Michael F. Hagan

Self-assembled monolayers of microparticles encoding Archimedean and non-regular tessellations promise unprecedented structure-property relationships for a wide spectrum of applications in fields ranging from optoelectronics to surface…

Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial-mesenchymal transitions or the formation of spheroidal aggregates, are often associated…

生物物理 · 物理学 2016-12-22 Bart Smeets , Ricard Alert , Jiri Pesek , Ignacio Pagonabarraga , Herman Ramon , Romaric Vincent

Cuttlebone, the sophisticated buoyancy device of cuttlefish, is made of extensive superposed chambers that have a complex internal arrangement of calcified pillars and organic membranes. It has not been clear how this structure is…

The use of colloidal supported lipid bilayers (CSLBs) has recently been extended to create colloidal joints, that - in analogy to their macroscopic counterparts - can flexibly connect colloidal particles. These novel elements enable the…

软凝聚态物质 · 物理学 2018-12-20 Melissa Rinaldin , Ruben W. Verweij , Indrani Chakraborty , Daniela J. Kraft

Mechanical force regulates the formation and growth of cell-cell junctions. Cadherin is a prominent homotypic cell adhesion molecule that plays a crucial role in establishment of intercellular adhesion. It is known that the transmitted…

生物物理 · 物理学 2017-10-11 Mohammad Tehrani , Alireza Sarvestani
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