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Dynamic treatment regimes (DTRs) are used in medicine to tailor sequential treatment decisions to patients by considering patient heterogeneity. Common methods for learning optimal DTRs, however, have shortcomings: they are typically based…

机器学习 · 统计学 2023-06-21 Theresa Blümlein , Joel Persson , Stefan Feuerriegel

Recent advancements in Large Language Models (LLMs) have positioned them as powerful tools for clinical decision-making, with rapidly expanding applications in healthcare. However, concerns about bias remain a significant challenge in the…

人工智能 · 计算机科学 2024-10-23 Kenza Benkirane , Jackie Kay , Maria Perez-Ortiz

Access to real-world healthcare data is limited by stringent privacy regulations and data imbalances, hindering advancements in research and clinical applications. Synthetic data presents a promising solution, yet existing methods often…

机器学习 · 计算机科学 2025-03-11 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

We propose a categorical matrix factorization method to infer latent diseases from electronic health records (EHR) data in an unsupervised manner. A latent disease is defined as an unknown biological aberration that causes a set of common…

应用统计 · 统计学 2019-02-15 Yang Ni , Peter Mueller , Yuan Ji

Phenotyping is the process of distinguishing groups of patients to identify different types of disease progression. A recent trend employs low-rank matrix and tensor factorization methods for their capability of dealing with multi-modal,…

机器学习 · 计算机科学 2025-06-26 Cristian Minoccheri , Sophia Tesic , Kayvan Najarian , Ryan Stidham

Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…

信号处理 · 电气工程与系统科学 2021-10-13 Mahdieh Kazemimoghadam , Nicholas P. Fey

In this paper, we propose a new variant of Linear Discriminant Analysis (LDA) to solve multi-label classification tasks. The proposed method is based on a probabilistic model for defining the weights of individual samples in a weighted…

机器学习 · 计算机科学 2020-04-10 Lei Xu , Jenni Raitoharju , Alexandros Iosifidis , Moncef Gabbouj

Temporal anomaly detection looks for irregularities over space-time. Unsupervised temporal models employed thus far typically work on sequences of feature vectors, and much less on temporal multiway data. We focus our investigation on…

机器学习 · 计算机科学 2020-09-22 Duc Nguyen , Phuoc Nguyen , Kien Do , Santu Rana , Sunil Gupta , Truyen Tran

After performing comparison of the performance of seven different machine learning models on detection depression tasks to show that the choice of features is essential, we compare our methods and results with the published work of other…

机器学习 · 统计学 2020-06-12 Milena Čukić Radenković , David Pokrajac , Victoria Lopez

Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…

计算机视觉与模式识别 · 计算机科学 2020-08-04 Pavan Rajkumar Magesh , Richard Delwin Myloth , Rijo Jackson Tom

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

图像与视频处理 · 电气工程与系统科学 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Diagnostic processes for complex cyber-physical systems often require extensive prior knowledge in the form of detailed system models or comprehensive training data. However, obtaining such information poses a significant challenge. To…

Driven by the dual principles of smart education and artificial intelligence technology, the online education model has rapidly emerged as an important component of the education industry. Cognitive diagnostic technology can utilize…

人工智能 · 计算机科学 2025-10-28 Zhifeng Wang , Meixin Su , Yang Yang , Chunyan Zeng , Lizhi Ye

Medical image segmentation is a fundamental task in numerous medical engineering applications. Recently, language-guided segmentation has shown promise in medical scenarios where textual clinical reports are readily available as semantic…

计算机视觉与模式识别 · 计算机科学 2026-01-23 Mingjian Li , Mingyuan Meng , Shuchang Ye , Michael Fulham , Lei Bi , Jinman Kim

Mental disorders are clinically significant patterns of behavior that are associated with stress and/or impairment in social, occupational, or family activities. People suffering from such disorders are often misjudged and poorly diagnosed…

机器学习 · 计算机科学 2025-09-03 Abu Shad Ahammed , Sayeri Mukherjee , Roman Obermaisser

Traditional Chinese Medicine theory is built on imagistic thinking, in which medical principles and diagnostic and therapeutic logic are structured through metaphor and metonymy. However, existing English translations largely rely on…

计算与语言 · 计算机科学 2025-12-16 Jiatong Han

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

Melanoma is a type of skin cancer developed from melanocytes. It is one of the most lethal types of cancer, accounting for approximately 75% of skin cancer deaths. Late stage melanoma is very difficult to treat, since the cancer cells are…

定量方法 · 定量生物学 2018-11-28 Xue Teng , Fuad Gwadry , Haley McConkey , Scott Ernst , Femida Gwadry-Sridhar

Metabolic disorders, particularly type 2 diabetes mellitus (T2DM), represent a significant global health burden, disproportionately impacting genetically predisposed populations such as the Pima Indians (a Native American tribe from south…

机器学习 · 计算机科学 2025-09-24 Iram Wajahat , Amritpal Singh , Fazel Keshtkar , Syed Ahmad Chan Bukhari

Unsupervised learning aims at the discovery of hidden structure that drives the observations in the real world. It is essential for success in modern machine learning. Latent variable models are versatile in unsupervised learning and have…

机器学习 · 计算机科学 2016-06-13 Furong Huang
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