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Clinical diagnosis guidelines aim at specifying the steps that may lead to a diagnosis. Inspired by guidelines, we aim to learn the optimal sequence of actions to perform in order to obtain a correct diagnosis from electronic health…

机器学习 · 计算机科学 2023-11-16 Lillian Muyama , Antoine Neuraz , Adrien Coulet

Access to electronic health record (EHR) data has motivated computational advances in medical research. However, various concerns, particularly over privacy, can limit access to and collaborative use of EHR data. Sharing synthetic EHR data…

机器学习 · 计算机科学 2018-01-15 Edward Choi , Siddharth Biswal , Bradley Malin , Jon Duke , Walter F. Stewart , Jimeng Sun

Cancer is one of the leading causes of death worldwide. It is caused by a variety of genetic mutations, which makes every instance of the disease unique. Since chemotherapy can have extremely severe side effects, each patient requires a…

Appropriate medication dosages in the intensive care unit (ICU) are critical for patient survival. Heparin, used to treat thrombosis and inhibit blood clotting in the ICU, requires careful administration due to its complexity and…

机器学习 · 计算机科学 2025-12-09 Yooseok Lim , Inbeom Park , Sujee Lee

Combination therapies are often needed for effective clinical outcomes in the management of complex diseases, but presently they are generally based on empirical clinical experience. Here we suggest a novel application of search algorithms,…

Sequential diagnosis prediction on the Electronic Health Record (EHR) has been proven crucial for predictive analytics in the medical domain. EHR data, sequential records of a patient's interactions with healthcare systems, has numerous…

机器学习 · 计算机科学 2021-09-08 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang

Diabetic Retinopathy (DR) is a prevalent illness associated with Diabetes which, if left untreated, can result in irreversible blindness. Deep Learning based systems are gradually being introduced as automated support for clinical…

图像与视频处理 · 电气工程与系统科学 2023-12-14 Samrat Mukherjee , Dibyanayan Bandyopadhyay , Baban Gain , Asif Ekbal

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

信息检索 · 计算机科学 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao

The continuously increasing cost of the US healthcare system has received significant attention. Central to the ideas aimed at curbing this trend is the use of technology, in the form of the mandate to implement electronic health records…

信息检索 · 计算机科学 2017-03-24 Pranjul Yadav , Michael Steinbach , Vipin Kumar , Gyorgy Simon

Causal inference on the average treatment effect (ATE) using non-probability samples, such as electronic health records (EHR), faces challenges from sample selection bias and high-dimensional covariates. This requires considering a…

统计方法学 · 统计学 2024-03-28 Jiacong Du , Xu Shi , Donglin Zeng , Bhramar Mukherjee

We propose machine learning algorithms to automatically detect and predict clopidogrel treatment failure using longitudinal structured electronic health records (EHR). By drawing analogies between natural language and structured EHR, we…

机器学习 · 计算机科学 2023-10-16 Samuel Kim , In Gu Sean Lee , Mijeong Irene Ban , Jane Chiang

Motivation: Drug repurposing is a viable solution for reducing the time and cost associated with drug development. However, thus far, the proposed drug repurposing approaches still need to meet expectations. Therefore, it is crucial to…

机器学习 · 计算机科学 2024-05-21 Ali Gharizadeh , Karim Abbasi , Amin Ghareyazi , Mohammad R. K. Mofrad , Hamid R. Rabiee

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

机器学习 · 计算机科学 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

The presence of detailed clinical information in electronic health record (EHR) systems presents promising prospects for enhancing patient care through automated retrieval techniques. Nevertheless, it is widely acknowledged that accessing…

There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance…

机器学习 · 统计学 2017-03-27 Long Ho , David Ledbetter , Melissa Aczon , Randall Wetzel

Heterogeneous treatment effect models allow us to compare treatments at subgroup and individual levels, and are of increasing popularity in applications like personalized medicine, advertising, and education. In this talk, we first survey…

统计方法学 · 统计学 2022-01-28 Zijun Gao , Trevor Hastie

Personalized medicine seeks to identify the causal effect of treatment for a particular patient as opposed to a clinical population at large. Most investigators estimate such personalized treatment effects by regressing the outcome of a…

机器学习 · 统计学 2021-09-02 Eric V. Strobl , Shyam Visweswaran

Objective: To determine if a realistic, but computationally efficient model of the electrocardiogram can be used to pre-train a deep neural network (DNN) with a wide range of morphologies and abnormalities specific to a given condition -…

机器学习 · 计算机科学 2022-01-03 Ismail Sadiq , Erick A. Perez-Alday , Amit J. Shah , Ali Bahrami Rad , Reza Sameni , Gari D. Clifford

Electronic Health Records (EHRs) exhibit a high amount of missing data due to variations of patient conditions and treatment needs. Imputation of missing values has been considered an effective approach to deal with this challenge. Existing…

机器学习 · 计算机科学 2022-10-25 Yuxi Liu , Shaowen Qin , Zhenhao Zhang , Wei Shao

A key output of network meta-analysis (NMA) is the relative ranking of treatments; nevertheless, it has attracted substantial criticism. Existing ranking methods often lack clear interpretability and fail to adequately account for…