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Infectious disease surveillance is of great importance for the prevention of major outbreaks. Syndromic surveillance aims at developing algorithms which can detect outbreaks as early as possible by monitoring data sources which allow to…

机器学习 · 计算机科学 2021-02-01 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

Metasurfaces enable exceptional control over the light with surface-confined planar components, offering the fascinating possibility of very dense integration and miniaturization in photonics. Here, we design, fabricate and experimentally…

Signal localization is a spectrum sensing problem that jointly detects the presence of a signal and estimates a center frequency and bandwidth. This is a step beyond most spectrum sensing work which estimates "present" or "not present"…

信号处理 · 电气工程与系统科学 2021-10-05 Nathan West , Tamoghna Roy , Timothy O'Shea

The prediction modeling of drug-target interactions is crucial to drug discovery and design, which has seen rapid advancements owing to deep learning technologies. Recently developed methods, such as those based on graph neural networks…

定量方法 · 定量生物学 2025-11-19 Xinnan Zhang , Jialin Wu , Junyi Xie , Tianlong Chen , Kaixiong Zhou

Two dimensional nuclear magnetic resonance (NMR) spectroscopy is one of the major tools for analysing the chemical structure of organic molecules and proteins. Despite its power, this technique requires long measurement times, which,…

Very high dimensional nonlinear systems arise in many engineering problems due to semi-discretization of the governing partial differential equations, e.g. through finite element methods. The complexity of these systems present…

Semantic similarity measures (SSMs) refer to a set of algorithms used to quantify the similarity of two or more terms belonging to the same ontology. Ontology terms may be associated to concepts, for instance in computational biology gene…

分子网络 · 定量生物学 2013-05-22 Pietro Hiram Guzzi , Simone Truglia , Pierangelo Veltri , Mario Cannataro

In many mechanical, electrical, and general physical systems evolving over time or space, spectral analysis methods as Fast Fourier Transform (FFT), Short Term Fourier Transform (STFT), Power Spectrum Density (PSD) plays a very important…

信号处理 · 电气工程与系统科学 2023-06-21 Andreas Tuor , Nico Canzani , Tobias Rüggeberg , Stefan Gorenflo , Gerd Simons , Bruno Bättig , Daniel Iseli

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

基因组学 · 定量生物学 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan

The precise optical, label-free, measurement of mass at the nanoscale has been significantly advanced by techniques based on interferometric scattering, such as mass photometry (MP). These methods exploit the interference between a…

光学 · 物理学 2025-01-14 Jan Becker

Optical metasurfaces are conventionally viewed as organized flat arrays of photonic or plasmonic nanoresonators, also called metaatoms. These metasurfaces are typically highly ordered and fabricated with precision using expensive tools.…

光学 · 物理学 2025-03-26 P. Lalanne , M Chen , C. Rockstuhl , A. Sprafke , A. Dmitriev , K. Vynck

Nuclear Magnetic Resonance (NMR) spectroscopy is an important analytical tool in chemistry, biology, and life science, but it suffers from relatively low sensitivity and long acquisition time. Thus, improving the apparent signal-to-noise…

化学物理 · 物理学 2020-07-27 Tianyu Qiu , Zi Wang , Huiting Liu , Di Guo , Xiaobo Qu

Recently, machine learning-based semantic segmentation algorithms have demonstrated their potential to accurately segment regions and contours in medical images, allowing the precise location of anatomical structures and abnormalities.…

计算机视觉与模式识别 · 计算机科学 2024-03-26 Yifei Wang , Chuhong Zhu

X-ray Photoelectron Spectroscopy (XPS) is a crucial technique for material surface analysis, yet interpreting its spectra is often challenging for both human analysts and automated methods due to the prevalence of variable spectral shifts…

材料科学 · 物理学 2026-03-06 Issa Saddiq , Yuxin Fan , Robert G. Palgrave , Mark A. Isaacs , David Morgan , Keith T. Butler

We present a new experimental-computational technology of inferring network models that predict the response of cells to perturbations and that may be useful in the design of combinatorial therapy against cancer. The experiments are…

Multi-dimensional magnetic resonance spectroscopy is an important tool for studying molecular structures, interactions and dynamics in bio-engineering. The data acquisition time, however, is relatively long and non-uniform sampling can be…

医学物理 · 物理学 2017-01-26 Xiaobo Qu , Jiaxi Ying , Jian-Feng Cai , Zhong Chen

Magnetic Resonance Fingerprinting (MRF) is an imaging technique acquiring unique time signals for different tissues. Although the acquisition is highly accelerated, the reconstruction time remains a problem, as the state-of-the-art template…

Regular sequences are natural generalisations of fixed points of constant-length substitutions on finite alphabets, that is, of automatic sequences. Using the harmonic analysis of measures associated with substitutions as motivation, we…

数论 · 数学 2021-08-12 Michael Coons , James Evans , Neil Manibo

Mass spectrometry-based metabolomic analysis depends upon the identification of spectral peaks by their mass and retention time. Statistical analysis that follows the identification currently relies on one main peak of each compound.…

定量方法 · 定量生物学 2014-03-20 Tommi Suvitaival , Simon Rogers , Samuel Kaski

Embedded devices are omnipresent in modern networks including the ones operating inside critical environments. However, due to their constrained nature, novel mechanisms are required to provide external, and non-intrusive anomaly detection.…

密码学与安全 · 计算机科学 2023-02-07 Kurt A. Vedros , Georgios Michail Makrakis , Constantinos Kolias , Robert C. Ivans , Craig Rieger